Stage before biopsy: define lesion (X‑ray/MRI) and search for primaries (CT CAP, bone scan/PET). Adult common cause is metastasis (BLT KP) or myeloma; in children, benign lesions (UBC/ABC, fibrous dysplasia). Biopsy tract must align with planned incision; core biopsy preferred; avoid contaminating compartments. Stabilize impending/complete fractures with nails/plates ± cement; endoprosthesis for major destruction. Adjuvant systemic therapy and radiotherapy per histology; bisphosphonates/denosumab in metastasis.
What is the most common cause of pathological fractures in adults?
Which imaging modality is preferred for evaluating soft tissue and marrow involvement in suspected pathological fractures?
In the workup of a pathological fracture, what is the purpose of conducting a CT scan of the chest, abdomen, and pelvis (CT CAP)?
What is the recommended type of biopsy for suspected bone tumors in the context of a pathological fracture?
Which of the following is a common benign lesion that can cause pathological fractures in children?
What is a key clinical feature that raises suspicion for an underlying neoplastic process in a patient with a pathological fracture?
In the management of a pathological fracture with significant bone destruction, which surgical intervention is often employed?
What type of lesion is indicated by a lytic bone lesion seen on X-ray?
Which of the following treatments may be indicated for metastatic bone disease associated with pathological fractures?
Which of the following is NOT a common site for pathological fractures?
