Locally aggressive benign tumor in skeletally mature adults (20–40 yrs). Campanacci classification: Grade I (latent), II (active), III (aggressive with soft tissue extension). X-ray: eccentric lytic lesion, soap-bubble appearance. Treatment: extended curettage with adjuvants, PMMA, or wide excision. Denosumab indicated in sacral/spinal or unresectable lesions.
What is the most common age group for the presentation of Giant Cell Tumor (GCT) of bone?
In the Campanacci classification, which grade of Giant Cell Tumor is characterized by well-defined margins with a sclerotic rim and an intact cortex?
Which imaging modality is essential for preoperative planning to define cortical integrity and soft tissue extension in Giant Cell Tumor?
What is the most common treatment approach for Campanacci Grade II Giant Cell Tumor?
Which of the following features is characteristic of Campanacci Grade III Giant Cell Tumor?
Which of the following statements is true regarding the epidemiology of Giant Cell Tumor?
In cases of Giant Cell Tumor involving the sacrum or spine, which treatment option is most appropriate if the lesion is unresectable?
What percentage of Giant Cell Tumors can metastasize to the lung?
What is the characteristic radiographic appearance of Grade II Giant Cell Tumor?
The 'soap-bubble' appearance on X-ray is most commonly associated with which grade of Giant Cell Tumor?
