Orthonotes
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Evidence Search

Search reputable indexed orthopaedic literature from multiple scholarly sources, classify the evidence, and link papers directly to wiki topics and cases.

Sources: PubMed, Europe PMC, Crossref

Linking results to Wiki: Bone Tumor Biopsy Principles
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Results are classified automatically from source metadata across PubMed, Europe PMC, and Crossref.
PubMed Crossref
PubMed Randomized Controlled Trial Evidence High

ADT with SBRT versus SBRT alone for hormone-sensitive oligorecurrent prostate cancer (RADIOSA): a randomised, open-label, phase 2 clinical trial.

The Lancet. Oncology | 2025 | Marvaso G, Corrao G, Zaffaroni M, Vincini MG

[Indexed for MEDLINE] Conflict of interest statement: Declaration of interests The Division of Radiation Oncology of the European Institute of Oncology IRCCS received research funding from the Italian Association for Cancer Research, Fondazione Istituto Europeo di Oncologia-Centro Cardiologico Monzino, Accuray, and Ion Beam applications. NF has received honoraria for consulting...

PubMed Guideline / Consensus Evidence High

Radiation Therapy for Solitary Plasmacytoma and Multiple Myeloma: Guidelines From the International Lymphoma Radiation Oncology Group.

International journal of radiation oncology, biology, physics | 2018 | Tsang RW, Campbell BA, Goda JS, Kelsey CR

[Indexed for MEDLINE] 3. Immunity. 2025 Jan 14;58(1):40-58. doi: 10.1016/j.immuni.2024.12.009. Adaptations of neutrophils in cancer. Ng M(1), Cerezo-Wallis D(2), Ng LG(3), Hidalgo A(4). Author information: (1)Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A(∗)STAR), Singapore, Singapore. Electronic address: melissa_ng@immunol.a-star.edu.sg. (2...

PubMed Narrative Review Evidence Moderate

Adaptations of neutrophils in cancer.

Immunity | 2025 | Ng M, Cerezo-Wallis D, Ng LG, Hidalgo A

[Indexed for MEDLINE] Conflict of interest statement: Declaration of interests The authors declare no competing interests. 4. Cytometry B Clin Cytom. 2017 May;92(3):218-227. doi: 10.1002/cyto.b.21219. Epub 2015 Aug 18. Introduction to the diagnosis and classification of monocytic-lineage leukemias by flow cytometry. Matarraz S(1), Almeida J(1), Flores-Montero J(1), Lécrevisse Q...

PubMed Narrative Review Evidence Moderate

Pediatric Bone Tumors.

Surgical pathology clinics | 2025 | Alston ELJ, Ecklund K, Al-Ibraheemi A

[Indexed for MEDLINE] Conflict of interest statement: Disclosures The authors have nothing to disclose. 8. Neurosurgery. 1984 Nov;15(5):735-46. doi: 10.1227/00006123-198411000-00021. Sacral fractures. Schmidek HH, Smith DA, Kristiansen TK. The sacral spine has received relatively little attention in the orthopedic and neurosurgical literature, in part because of the infrequency...

PubMed Narrative Review Evidence Moderate

Biopsy Techniques for Musculoskeletal Tumors: Basic Principles and Specialized Techniques.

Current oncology (Toronto, Ont.) | 2024 | Mavrogenis AF, Altsitzioglou P, Tsukamoto S, Errani C

[Indexed for MEDLINE] Conflict of interest statement: The authors do not have conflicts of interest to declare. 18. Neurosurgery. 2017 Mar 1;80(3S):S124-S130. doi: 10.1093/neuros/nyw064. Spine Oncology - Primary Spine Tumors. Dea N(1), Gokaslan Z(2), Choi D(3), Fisher C(4). Author information: (1)Division of Neurosurgery, Department of Surgery, Université de Sherbrooke, Sherbro...

PubMed Narrative Review Evidence Moderate

Musculoskeletal Tumors.

Pediatric clinics of North America | 2020 | Singla A, Geller DS

[Indexed for MEDLINE] 6. Tech Vasc Interv Radiol. 2022 Mar;25(1):100800. doi: 10.1016/j.tvir.2022.100800. Epub 2022 Jan 16. Percutaneous bone biopsy. Masood S(1), Mallinson PI(2), Sheikh A(2), Ouellette H(2), Munk PL(2). Author information: (1)Vancouver General Hospital/ University of British Columbia, Vancouver, Canada. Electronic address: dr_salmanmasood@hotmail.com. (2)Vanco...

PubMed Narrative Review Evidence Moderate

Bone Cancer: Diagnosis and Treatment Principles.

American family physician | 2018 | Ferguson JL, Turner SP

[Indexed for MEDLINE] 2. Int J Radiat Oncol Biol Phys. 2018 Jul 15;101(4):794-808. doi: 10.1016/j.ijrobp.2018.05.009. Epub 2018 Jun 20. Radiation Therapy for Solitary Plasmacytoma and Multiple Myeloma: Guidelines From the International Lymphoma Radiation Oncology Group. Tsang RW(1), Campbell BA(2), Goda JS(3), Kelsey CR(4), Kirova YM(5), Parikh RR(6), Ng AK(7), Ricardi U(8), Su...

PubMed Narrative Review Evidence Moderate

Introduction to the diagnosis and classification of monocytic-lineage leukemias by flow cytometry.

Cytometry. Part B, Clinical cytometry | 2017 | Matarraz S, Almeida J, Flores-Montero J, Lécrevisse Q

[Indexed for MEDLINE] 5. Pediatr Clin North Am. 2020 Feb;67(1):227-245. doi: 10.1016/j.pcl.2019.09.014. Musculoskeletal Tumors. Singla A(1), Geller DS(2). Author information: (1)Department of Orthopaedic Surgery, Montefiore Medical Center, 3400 Bainbridge Avenue, 6th Floor, Bronx, NY 10467, USA. Electronic address: dgeller@montefiore.org. (2)Department of Orthopaedic Surgery, M...

PubMed Narrative Review Evidence Moderate

Spine Oncology - Primary Spine Tumors.

Neurosurgery | 2017 | Dea N, Gokaslan Z, Choi D, Fisher C

[Indexed for MEDLINE] 19. J Exp Clin Cancer Res. 2025 Aug 4;44(1):225. doi: 10.1186/s13046-025-03478-5. Repurposed clindamycin suppresses pyroptosis in tumor-associated macrophages through Inhibition of caspase-1. Weich A(#)(1)(2)(3), Berges J(#)(4), Flamann C(4), Bitterer K(4), Singh KP(5), Chambers D(6), Lischer C(4), Lai X(1)(7), Wolkenhauer O(5)(8), Berking C(1)(2)(3), Krön...

PubMed Case Report / Series Evidence Low

Manubriectomy made easy.

Multimedia manual of cardiothoracic surgery : MMCTS | 2024 | Mughal AZ, El-Zeki A, Oliemy A, Habib AM

[Indexed for MEDLINE] 14. Crit Rev Oral Biol Med. 1997;8(2):201-16. doi: 10.1177/10454411970080020701. Graft-vs.-host disease. Woo SB(1), Lee SJ, Schubert MM. Author information: (1)Division of Oral Medicine and Dentistry, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA. Bone marrow transplantation (BMT) is the treatment of choice for many leukemias, lymphomas, b...

PubMed Original Article Evidence Unclassified

KPNA2 promotes osteosarcoma progression by regulating the alternative splicing of DDX3X mediated by YBX1.

Oncogene | 2025 | Cao L, Jia K, Van Tine BA, Yu Y

[Indexed for MEDLINE] Conflict of interest statement: Competing interests: LC, KJ, YY, YP, XC, QP, WY, ZZ, ZS, and WW report no conflicts of interest. VT BA reports research grants from Polaris, Pfizer, Merck, Tracon Pharma, GlaxoSmithKline; consulting fees from Bayer, Cytokinetics Inc., Deciphera Pharmaceuticals, Daiichi Sankyo, EcoR1, Advenchen, Putnam, Salarius Pharmaceutica...

PubMed Original Article Evidence Unclassified

MARCH8/NSUN6/ROS-mediated DNA damage positive feedback loop regulates cisplatin resistance in osteosarcoma.

Cell death and differentiation | 2025 | He M, Li T, Wang A, Liu Y

[Indexed for MEDLINE] Conflict of interest statement: Competing interests: The authors declare no competing interests. Ethical approval and consent to participate: Ethical approval for the study was granted by the Harbin Medical University Animal Ethical committee, in accordance with the principles of the Declaration of Helsinki. 16. Cell Death Dis. 2025 Oct 7;16(1):712. doi: 1...

PubMed Original Article Evidence Unclassified

HMGB1 orchestrates tumor-osteoclast crosstalk to drive bone metastasis in hepatocellular carcinoma.

Cell death & disease | 2025 | Chen YZ, Xu D, Jia YX, Ma J

[Indexed for MEDLINE] Conflict of interest statement: Competing interests: The authors declare no competing interests. Ethics approval and consent to participate: This study was approved by the Ethics Committee of Shanghai East Hospital (No.2022250). All procedures involving human participants adhered to the principles of the Declaration of Helsinki and informed consent was obt...

PubMed Original Article Evidence Unclassified

Repurposed clindamycin suppresses pyroptosis in tumor-associated macrophages through Inhibition of caspase-1.

Journal of experimental & clinical cancer research : CR | 2025 | Weich A, Berges J, Flamann C, Bitterer K

[Indexed for MEDLINE] Conflict of interest statement: Declarations. Ethics approval and consent to participate: The studies involving human subjects or material were reviewed and approved by the Ethics Committee of the Friedrich-Alexander Universität Erlangen-Nürnberg. The principal investigator and all other investigators ensured that the studies were conducted in full conform...

PubMed Original Article Evidence Unclassified

The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma.

Cell death and differentiation | 2025 | Ohata Y, Ali MM, Tsubakihara Y, Itoh Y

[Indexed for MEDLINE] Conflict of interest statement: Competing interests: The authors declare no competing interests. Ethics approval and consent to participate: All the procedures were performed in accordance with the guidelines for Ethical Conduct in the Care and Use of Animals as stated in The International Guiding Principles for Biomedical Research involving Animals, devel...

PubMed Original Article Evidence Unclassified

IL-5-producing CD4(+) T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer.

Cancer cell | 2023 | Blomberg OS, Spagnuolo L, Garner H, Voorwerk L

[Indexed for MEDLINE] Conflict of interest statement: Declaration of interests O.S.B., H.G., L.S., L.V., O.I.I., E.v.D., N.B., C.K., M.D., K. Kersten, M.B., D.P., C.-S.H., K.V., E.A.M.R., D.K., L.H., K. Kos, I.S.A., P.K., R.B., and D.S.T. have no competing interests to declare. M.C. reports funding to the institute from BMS and Roche/Genentech and an advisory role for BMS, outs...

PubMed Original Article Evidence Unclassified

Percutaneous bone biopsy.

Techniques in vascular and interventional radiology | 2022 | Masood S, Mallinson PI, Sheikh A, Ouellette H

[Indexed for MEDLINE] 7. Surg Pathol Clin. 2025 Sep;18(3):581-595. doi: 10.1016/j.path.2025.01.003. Epub 2025 Feb 18. Pediatric Bone Tumors. Alston ELJ(1), Ecklund K(2), Al-Ibraheemi A(3). Author information: (1)Department of Pathology, Boston Children's Hospital, Boston, MA, USA. (2)Department of Radiology, Boston Children's Hospital, Boston, MA, USA. (3)Department of Patholog...

PubMed Narrative Review Evidence Moderate

The biopsy.

Instructional course lectures | 2004 | Scarborough MT

[Indexed for MEDLINE] 11. Cancer Cell. 2023 Jan 9;41(1):106-123.e10. doi: 10.1016/j.ccell.2022.11.014. Epub 2022 Dec 15. IL-5-producing CD4(+) T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer. Blomberg OS(1), Spagnuolo L(2), Garner H(2), Voorwerk L(3), Isaeva OI(4), van Dyk E(5), Bakker N(2), Chalabi M(6), Klaver C(3), Duijst...

PubMed Narrative Review Evidence Moderate

Graft-vs.-host disease.

Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists | 1997 | Woo SB, Lee SJ, Schubert MM

[Indexed for MEDLINE] 15. Cell Death Differ. 2025 Dec;32(12):2412-2426. doi: 10.1038/s41418-025-01544-1. Epub 2025 Jul 19. MARCH8/NSUN6/ROS-mediated DNA damage positive feedback loop regulates cisplatin resistance in osteosarcoma. He M(#)(1)(2), Li T(#)(2), Wang A(#)(2), Liu Y(2), Wang X(2), Liu Z(3), Xie J(1), Wang Y(2), Wang Y(4), Ren Z(1), Ge S(2), Yang L(5)(6)(7), Yuan Y(8)...

PubMed Narrative Review Evidence Moderate

Sacral fractures.

Neurosurgery | 1984 | Schmidek HH, Smith DA, Kristiansen TK

[Indexed for MEDLINE] 9. Lancet Oncol. 2025 Mar;26(3):300-311. doi: 10.1016/S1470-2045(24)00730-7. ADT with SBRT versus SBRT alone for hormone-sensitive oligorecurrent prostate cancer (RADIOSA): a randomised, open-label, phase 2 clinical trial. Marvaso G(1), Corrao G(1), Zaffaroni M(2), Vincini MG(3), Lorubbio C(1), Gandini S(4), Fodor C(3), Netti S(4), Zerini D(3), Luzzago S(5...