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Evidence Search

Search reputable indexed orthopaedic literature from multiple scholarly sources, classify the evidence, and link papers directly to wiki topics and cases.

Sources: PubMed, Europe PMC, Crossref

Linking results to Wiki: Soft Tissue Sarcoma — Enneking
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Results are classified automatically from source metadata across PubMed, Europe PMC, and Crossref.
PubMed Crossref
PubMed Systematic Review / Meta-analysis Evidence High

Clinical effectiveness of Enneking appropriate versus Enneking inappropriate procedure in patients with primary osteosarcoma of the spine: a systematic review with meta-analysis.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society | 2020 | Pombo B, Cristina Ferreira A, Cardoso P, Oliveira A

[Indexed for MEDLINE] 3. J Neurosurg Spine. 2024 Sep 27;41(6):708-715. doi: 10.3171/2024.5.SPINE231401. Print 2024 Dec 1. Intentional Enneking-inappropriate surgery and high-energy particle therapy for unresectable osteogenic sarcoma of the spine: a retrospective study. Evangelisti G(#)(1), Falzetti L(#)(1), Altorfer FCS(2), Bandiera S(1), Barbanti Brodano G(1), Cianchetti M(3)...

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PubMed Systematic Review / Meta-analysis Evidence High

Surgical Outcomes After Limb-Sparing Resection and Reconstruction for Pelvic Sarcoma: A Systematic Review.

JBJS reviews | 2018 | Wilson RJ, Freeman TH Jr, Halpern JL, Schwartz HS

[Indexed for MEDLINE] 15. Spine (Phila Pa 1976). 1997 May 1;22(9):1036-44. doi: 10.1097/00007632-199705010-00020. Primary bone tumors of the spine. Terminology and surgical staging. Boriani S(1), Weinstein JN, Biagini R. Author information: (1)Department of Orthopaedics and Traumatology, Ospedale Maggiore, Bologna, Italy. Appropriate application of an oncologic staging system i...

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PubMed Systematic Review / Meta-analysis Evidence High

A meta-analysis of limb-salvage versus amputation in the treatment of patients with Enneking‡U pathologic fracture osteosarcoma.

Indian journal of cancer | 2015 | Jiang F, Shi Y, Li GJ, Zhou F

[Indexed for MEDLINE] 8. Arch Orthop Trauma Surg. 2010 Feb;130(2):171-6. doi: 10.1007/s00402-009-0945-2. Epub 2009 Jul 31. Total femur replacement. Ahmed AR(1). Author information: (1)Department of Orthopaedic Surgery, Alexandria University, Smouha Landmark Building 44-D, 14th May St., Smouha, Alexandria, Egypt. egyptadel28@hotmail.com BACKGROUND: Total femoral replacement afte...

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PubMed Systematic Review / Meta-analysis Evidence High

Prognostic Significance of Survivin Expression in Osteosarcoma Patients: A Meta-Analysis.

Medical science monitor : international medical journal of experimental and clinical research | 2015 | Liu Y, Teng Z, Wang Y, Gao P

[Indexed for MEDLINE] 10. Orthopedics. 1986 Dec;9(12):1639-52. doi: 10.3928/0147-7447-19861201-07. A modular femur-tibia reconstruction system. Kotz R, Ritschl P, Trachtenbrodt J. A 26 piece modular system for the reconstruction of the bones of the lower extremity from the femoral head to the distal third of the tibia is described. This modular system can be implanted without c...

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PubMed Narrative Review Evidence Moderate

Application and improvement of ipsilateral clavicle turnover during proximal humeral tumorous bone defect repair.

Injury | 2021 | Han J, Wang W, Yu X, Li X

[Indexed for MEDLINE] Conflict of interest statement: Declaration of Competing Interest The authors declare that they have no conflict of interest. 14. JBJS Rev. 2018 Apr;6(4):e10. doi: 10.2106/JBJS.RVW.17.00072. Surgical Outcomes After Limb-Sparing Resection and Reconstruction for Pelvic Sarcoma: A Systematic Review. Wilson RJ(1), Freeman TH Jr(2), Halpern JL(2), Schwartz HS(2...

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PubMed Narrative Review Evidence Moderate

Staging of Bone and Soft-tissue Sarcomas.

The Journal of the American Academy of Orthopaedic Surgeons | 2018 | Steffner RJ, Jang ES

[Indexed for MEDLINE] 2. Eur Spine J. 2020 Feb;29(2):238-247. doi: 10.1007/s00586-019-06099-7. Epub 2019 Aug 13. Clinical effectiveness of Enneking appropriate versus Enneking inappropriate procedure in patients with primary osteosarcoma of the spine: a systematic review with meta-analysis. Pombo B(1), Cristina Ferreira A(2), Cardoso P(3)(4), Oliveira A(3)(4). Author informatio...

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PubMed Original Article Evidence Unclassified

ZDHHC9 promotes osteosarcoma progression via KRAS-associated enhancement of the RAS/MAPK signaling pathway.

Scientific reports | 2025 | Li Z, Li J, Wu Y, Luo Y

[Indexed for MEDLINE] Conflict of interest statement: Declarations. Competing interests: The authors declare no competing interests. 13. Injury. 2021 Oct;52(10):2941-2946. doi: 10.1016/j.injury.2021.04.063. Epub 2021 May 1. Application and improvement of ipsilateral clavicle turnover during proximal humeral tumorous bone defect repair. Han J(1), Wang W(2), Yu X(3), Li X(4), Wan...

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PubMed Original Article Evidence Unclassified

Intentional Enneking-inappropriate surgery and high-energy particle therapy for unresectable osteogenic sarcoma of the spine: a retrospective study.

Journal of neurosurgery. Spine | 2024 | Evangelisti G, Falzetti L, Altorfer FCS, Bandiera S

[Indexed for MEDLINE] 4. Rev Bras Ortop (Sao Paulo). 2021 Aug;56(4):411-418. doi: 10.1055/s-0040-1710331. Epub 2020 Sep 30. Updating on Bone and Soft Tissue Sarcomas Staging. Guedes A(1), Oliveira MBDR(2), Costa FM(3), de Melo AS(4). Author information: (1)Serviço de Ortopedia, Hospital Santa Izabel, Santa Casa de Misericórdia da Bahia, Salvador, BA, Brasil. (2)Serviço de Traum...

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PubMed Original Article Evidence Unclassified

Evaluation of the factors affecting survival and local recurrence in thigh soft tissue sarcomas.

Joint diseases and related surgery | 2024 | Yıldırım S, Çiftdemir M, Ustabaşıoğlu FE, Üstün F

[Indexed for MEDLINE] Conflict of interest statement: Conflict of Interest: The authors declared no conflicts of interest with respect to the authorship and/or publication of this article. 18. Bone Joint J. 2023 Dec 1;105-B(12):1314-1320. doi: 10.1302/0301-620X.105B12.BJJ-2023-0552.R1. Oncological and functional outcomes after resection of malignant tumours of the scapula. Broi...

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PubMed Original Article Evidence Unclassified

Oncological and functional outcomes after resection of malignant tumours of the scapula.

The bone & joint journal | 2023 | Broida SE, Sullivan MH, Barlow JD, Morrey M

[Indexed for MEDLINE] Conflict of interest statement: J. D. Barlow reports personal and institutional royalties and consulting payments from Stryker, unrelated to this study. M. Houdek reports consulting payments from Link Orthopedics, unrelated to this study, and a leadership or fiduciary role in the Musculoskeletal Tumor Society, the Connective Tissue Oncology Society, and th...

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PubMed Original Article Evidence Unclassified

Malignant Tumors of the Foot and Ankle.

Foot & ankle international | 2022 | Karaca MO, Başarır K, Merter A, Acar E

[Indexed for MEDLINE] Conflict of interest statement: Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. ICMJE forms for all authors are available online. 6. Acta Orthop Traumatol Turc. 2007 Aug-Oct;41(4):286-90. [Sarcomas of the hand]. [Article in Turkish]...

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PubMed Original Article Evidence Unclassified

Updating on Bone and Soft Tissue Sarcomas Staging.

Revista brasileira de ortopedia | 2021 | Guedes A, Oliveira MBDR, Costa FM, de Melo AS

Conflict of interest statement: Conflito de Interesses Os autores declaram não haver conflito de interesses. 5. Foot Ankle Int. 2022 Sep;43(9):1232-1241. doi: 10.1177/10711007221097654. Epub 2022 Jun 13. Malignant Tumors of the Foot and Ankle. Karaca MO(1), Başarır K(1), Merter A(1), Acar E(2), Özbek EA(1), Özyıldıran M(1), Yıldız HY(1). Author information: (1)Department of Ort...

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PubMed Original Article Evidence Unclassified

Circular RNA MTO1 intercorrelates with microRNA-630, both associate with Enneking stage and/or pathological fracture as well as prognosis in osteosarcoma patients.

Journal of clinical laboratory analysis | 2021 | Shi Z, Wen Y, Zhang S, Cheng X

[Indexed for MEDLINE] Conflict of interest statement: No potential conflict of interest was reported by the authors. 12. Sci Rep. 2025 Oct 14;15(1):35780. doi: 10.1038/s41598-025-13787-6. ZDHHC9 promotes osteosarcoma progression via KRAS-associated enhancement of the RAS/MAPK signaling pathway. Li Z(#)(1), Li J(#)(2), Wu Y(3), Luo Y(4), Zheng J(5), Shi J(6). Author information:...

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PubMed Original Article Evidence Unclassified

Pre-Operative chemotherapy response assessed by contrast-enhanced MRI can predict the prognosis of Enneking surgical margins in patients with osteosarcoma.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society | 2019 | He F, Qin L, Bao Q, Zang S

[Indexed for MEDLINE] 17. Jt Dis Relat Surg. 2024 Jan 1;35(1):130-137. doi: 10.52312/jdrs.2023.1289. Epub 2023 Nov 23. Evaluation of the factors affecting survival and local recurrence in thigh soft tissue sarcomas. Yıldırım S(1), Çiftdemir M, Ustabaşıoğlu FE, Üstün F, Usta U. Author information: (1)Lüleburgaz Devlet Hastanesi Ortopedi ve Travmatoloji Kliniği, 39750 Lüleburgaz,...

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Crossref Scholarly Work Evidence Unclassified

Soft Tissue Sarcoma

Oxford Scholarship Online | 2017 | Marianne Berwick, Charles Wiggins

Soft tissue sarcoma (STS) is a rare tumor, occurring in approximately one to four of every 100,000 individuals worldwide. Soft tissue sarcomas can form anywhere in the body, including muscle, tendons, fat, blood vessels, lymph vessels, nerves, and tissues around joints. They are most common in the head, neck, arms, legs, trunk, and abdomen. Prognosis is generally poor, with a r...

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PubMed Narrative Review Evidence Moderate

Primary bone tumors of the spine. Terminology and surgical staging.

Spine | 1997 | Boriani S, Weinstein JN, Biagini R

[Indexed for MEDLINE] 16. J Orthop Res. 2019 Jan;37(1):258-264. doi: 10.1002/jor.24143. Epub 2018 Oct 9. Pre-Operative chemotherapy response assessed by contrast-enhanced MRI can predict the prognosis of Enneking surgical margins in patients with osteosarcoma. He F(1), Qin L(2), Bao Q(1), Zang S(1), He Q(1), Qiu S(1)(3)(4), Shen Y(1)(3), Zhang W(1)(3). Author information: (1)De...

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PubMed Original Article Evidence Unclassified

Total femur replacement.

Archives of orthopaedic and trauma surgery | 2010 | Ahmed AR

[Indexed for MEDLINE] 9. Med Sci Monit. 2015 Sep 25;21:2877-85. doi: 10.12659/MSM.894448. Prognostic Significance of Survivin Expression in Osteosarcoma Patients: A Meta-Analysis. Liu Y(1), Teng Z(2), Wang Y(3), Gao P(3), Chen J(1). Author information: (1)Department of Orthopedics, Affiliated Hospital of Hebei University of Engineering, Handan, Hebei, China (mainland). (2)Depar...

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PubMed Original Article Evidence Unclassified

[Sarcomas of the hand].

Acta orthopaedica et traumatologica turcica | 2007 | Gürkan V, Ozger H

[Indexed for MEDLINE] 7. Indian J Cancer. 2015 Feb;51 Suppl 2:e21-4. doi: 10.4103/0019-509X.151997. A meta-analysis of limb-salvage versus amputation in the treatment of patients with Enneking‡U pathologic fracture osteosarcoma. Jiang F, Shi Y(1), Li GJ, Zhou F. Author information: (1)Department of Oncology, Huaihe Hospital Affiliated to Henan University, Kaifeng 475000, PR Chi...

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PubMed Original Article Evidence Unclassified

A modular femur-tibia reconstruction system.

Orthopedics | 1986 | Kotz R, Ritschl P, Trachtenbrodt J

[Indexed for MEDLINE] 11. J Clin Lab Anal. 2021 Nov;35(11):e23987. doi: 10.1002/jcla.23987. Epub 2021 Sep 20. Circular RNA MTO1 intercorrelates with microRNA-630, both associate with Enneking stage and/or pathological fracture as well as prognosis in osteosarcoma patients. Shi Z(1), Wen Y(2), Zhang S(3), Cheng X(4). Author information: (1)Hand and Foot Surgery, Xianning Central...

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PubMed Original Article Evidence Unclassified

A system of staging musculoskeletal neoplasms.

Clinical orthopaedics and related research | 1986 | Enneking WF

[Indexed for MEDLINE] 20. Clin Orthop Relat Res. 1993 Apr;(289):19-31. Principles of staging of soft-tissue sarcomas. Peabody TD(1), Simon MA. Author information: (1)University of Chicago Medical Center, Section of Orthopaedic Surgery and Rehabilitation Medicine, Illinois. The TNM staging system is a modus for diagnosis and treatment in which T is the extent of the tumor involv...

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