Application and improvement of ipsilateral clavicle turnover during proximal humeral tumorous bone defect repair.

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Abstract

[Indexed for MEDLINE] Conflict of interest statement: Declaration of Competing Interest The authors declare that they have no conflict of interest. 13. Med Sci Monit. 2015 Sep 25;21:2877-85. doi: 10.12659/MSM.894448. Prognostic Significance of Survivin Expression in Osteosarcoma Patients: A Meta-Analysis. Liu Y(1), Teng Z(2), Wang Y(3), Gao P(3), Chen J(1). Author information: (1)Department of Orthopedics, Affiliated Hospital of Hebei University of Engineering, Handan, Hebei, China (mainland). (2)Department of Orthopedics, The People's Hospital of Yuxi City, The 6th Affiliated Hospital of Kunming Medical University, Yuxi, Yunan, China (mainland). (3)Department of Pharmacy, Medical College of Hebei University of Engineering, Handan, Hebei, China (mainland). BACKGROUND: Osteosarcoma is the most common primary bone malignancy and has poor prognosis. Survivin has been identified as an independent prognostic factor for a majority of cancers. In the present study, we evaluated the effect of survivin expression on the clinical outcome of osteosarcoma patients. MATERIAL AND METHODS: Online electronic databases were searched for related articles published between 2000 and 2015. Odds ratio (OR) and risk ratio (RR) with their 95% confidence intervals (CI) were employed to calculate the significance. RESULTS: Overall, a total of 20 relevant studies were selected, including 1030 patients. No significant heterogeneity was observed among included studies (P>0.01, I2