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Evidence Search

Search reputable indexed orthopaedic literature from multiple scholarly sources, classify the evidence, and link papers directly to wiki topics and cases.

Sources: PubMed, Europe PMC, Crossref

Linking results to Wiki: Antibiotic Prophylaxis in Orthopaedics
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Results are classified automatically from source metadata across PubMed, Europe PMC, and Crossref.
PubMed Crossref
PubMed Guideline / Consensus Evidence High

European Society of Clinical Microbiology and Infectious Diseases/European Committee on infection control clinical guidelines on pre-operative decolonization and targeted prophylaxis in patients colonized by multidrug-resistant Gram-positive bacteria befo

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases | 2024 | Righi E, Mutters NT, Guirao X, Dolores Del Toro M

[Indexed for MEDLINE] 5. Orthopedics. 2015 Nov;38(11):e1025-33. doi: 10.3928/01477447-20151020-12. Acute Management of Open Fractures: An Evidence-Based Review. Halawi MJ, Morwood MP. Open fractures are complex injuries associated with high morbidity and mortality. Despite advances made in fracture care and infection prevention, open fractures remain a therapeutic challenge wit...

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PubMed Guideline / Consensus Evidence High

Controversies in orthopaedic oncology.

The bone & joint journal | 2024 | Jeys LM, Thorkildsen J, Kurisunkal V, Puri A

[Indexed for MEDLINE] Conflict of interest statement: A. Puri is a member of the editorial board of The Bone & Joint Journal. P. Ruggieri reports consulting fees from Exactech and Stryker, unrelated to this study. M. T. Houdek reports consulting fees from Link Orthopedics, unrelated to this study. E. Botello reports consulting fees, payment or honoraria for lectures, presentati...

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PubMed Systematic Review / Meta-analysis Evidence High

Antibiotic Prophylaxis for Orthopaedic Implant Removal: What Does the Evidence Say?

Current drug safety | 2023 | Rather IIG, Shafiq N, Pandey AK, Bhandari RK

[Indexed for MEDLINE] 17. J Chemother. 2001 Nov;13 Spec No 1(1):48-53. doi: 10.1179/joc.2001.13.Supplement-2.48. Antibiotic prophylaxis in orthopedic prosthetic surgery. de Lalla F(1). Author information: (1)Department of Infectious Diseases, S.Bortolo Hospital, Vicenza, Italy. fdl.vi@gpnet.it Staphylococci account for approximately 70% of postoperative infections in orthopedic...

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PubMed Systematic Review / Meta-analysis Evidence High

Prophylactic postoperative measures to minimize surgical site infections in spine surgery: systematic review and evidence summary.

The spine journal : official journal of the North American Spine Society | 2020 | Tan T, Lee H, Huang MS, Rutges J

[Indexed for MEDLINE] 9. Bone Joint J. 2024 May 1;106-B(5):425-429. doi: 10.1302/0301-620X.106B5.BJJ-2023-1381. Controversies in orthopaedic oncology. Jeys LM(1), Thorkildsen J(2), Kurisunkal V(1), Puri A(3), Ruggieri P(4), Houdek MT(5), Boyle RA(6), Ebeid W(7), Botello E(8), Morris GV(1); BOOM Consensus Scientific Committee; Laitinen MK(140); BOOM Consensus Scientific Committe...

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PubMed Narrative Review Evidence Moderate

Optimizing Antibiotic Therapy in Musculoskeletal Infections.

Infectious disease clinics of North America | 2025 | Cortés-Penfield NW, Justo JA, McCreary EK, Ryder JH

[Indexed for MEDLINE] 4. Clin Microbiol Infect. 2024 Dec;30(12):1537-1550. doi: 10.1016/j.cmi.2024.07.012. Epub 2024 Aug 21. European Society of Clinical Microbiology and Infectious Diseases/European Committee on infection control clinical guidelines on pre-operative decolonization and targeted prophylaxis in patients colonized by multidrug-resistant Gram-positive bacteria befo...

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PubMed Narrative Review Evidence Moderate

Preventing Orthopedic Infections.

Infectious disease clinics of North America | 2025 | Ritter AS, Mears S

[Indexed for MEDLINE] Conflict of interest statement: Disclosure The authors have nothing to disclose. No funding source was used for this article. 7. J Orthop Trauma. 2015 Dec;29 Suppl 12:S19-23. doi: 10.1097/BOT.0000000000000461. Infection in Orthopaedics. Cook GE(1), Markel DC, Ren W, Webb LX, McKee MD, Schemitsch EH. Author information: (1)*Institute of Biomaterials and Bio...

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PubMed Narrative Review Evidence Moderate

[Perioperative antibiotic prophylaxis in obesity].

Orthopadie (Heidelberg, Germany) | 2025 | Schnurr C

[Indexed for MEDLINE] Conflict of interest statement: Einhaltung ethischer Richtlinien. Interessenkonflikt: C. Schnurr gibt Beratertätigkeiten für Stryker und ZimmerBiomet an. Für diesen Beitrag wurden von den Autor/-innen keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien. 15. Expert Rev Me...

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PubMed Narrative Review Evidence Moderate

Fracture related infection and sepsis in orthopedic trauma: A review.

Surgery | 2024 | Dvorak JE, Lasinski AM, Romeo NM, Hirschfeld A

[Indexed for MEDLINE] 11. Orthop Nurs. 2023 Sep-Oct 01;42(5):312-316. doi: 10.1097/NOR.0000000000000972. Overview of Antibiotic Prophylaxis in Orthopaedic and Cardiac Procedures. Karapetyan K(1)(2)(3)(4), Mei S(1)(2)(3)(4), Choudhury A(1)(2)(3)(4), Cottreau J(1)(2)(3)(4). Author information: (1)Kristina Karapetyan, PharmD, PGY-2 Ambulatory Care Pharmacy Resident, Captain James...

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PubMed Narrative Review Evidence Moderate

Overview of Antibiotic Prophylaxis in Orthopaedic and Cardiac Procedures.

Orthopedic nursing | 2023 | Karapetyan K, Mei S, Choudhury A, Cottreau J

[Indexed for MEDLINE] Conflict of interest statement: The authors have no known conflicts of interest to disclose. 12. J Am Acad Orthop Surg. 2019 Apr 1;27(7):e301-e310. doi: 10.5435/JAAOS-D-17-00676. Gunshot Wounds to the Upper Extremity. Omid R(1), Stone MA, Zalavras CG, Marecek GS. Author information: (1)From the Department of Orthopaedic Surgery, University of Southern Cali...

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PubMed Narrative Review Evidence Moderate

Antibiotic prophylaxis in orthopedics-traumatology.

Orthopaedics & traumatology, surgery & research : OTSR | 2021 | Gaudias J

[Indexed for MEDLINE] 2. J Am Acad Orthop Surg. 2020 Apr 15;28(8):309-315. doi: 10.5435/JAAOS-D-18-00193. Antibiotic Prophylaxis in Open Fractures: Evidence, Evolving Issues, and Recommendations. Garner MR(1), Sethuraman SA, Schade MA, Boateng H. Author information: (1)From the Department of Orthopaedic Trauma (Dr. Garner, Dr. Boateng), Penn State College of Medicine, Milton S....

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PubMed Narrative Review Evidence Moderate

Antibiotic Prophylaxis in Open Fractures: Evidence, Evolving Issues, and Recommendations.

The Journal of the American Academy of Orthopaedic Surgeons | 2020 | Garner MR, Sethuraman SA, Schade MA, Boateng H

[Indexed for MEDLINE] 3. Infect Dis Clin North Am. 2025 Sep;39(3):361-382. doi: 10.1016/j.idc.2025.02.009. Epub 2025 Apr 11. Optimizing Antibiotic Therapy in Musculoskeletal Infections. Cortés-Penfield NW(1), Justo JA(2), McCreary EK(3), Ryder JH(4). Author information: (1)Division of Infectious Diseases, University of Nebraska Medical Center, Omaha, NE, USA. Electronic address...

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PubMed Narrative Review Evidence Moderate

Gunshot Wounds to the Upper Extremity.

The Journal of the American Academy of Orthopaedic Surgeons | 2019 | Omid R, Stone MA, Zalavras CG, Marecek GS

[Indexed for MEDLINE] 13. Hand Surg Rehabil. 2024 Sep;43(4):101753. doi: 10.1016/j.hansur.2024.101753. Epub 2024 Jul 26. Antibiotic prophylaxis in surgery for closed fracture of the hand. Lidauer K(1), Helenius I(2), Pääkkönen M(3). Author information: (1)Department of Hand and Upper Limb Surgery, Diseases of the Musculoskeletal System Division, Turku University Hospital, Unive...

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PubMed Narrative Review Evidence Moderate

Pin tract infection prophylaxis and treatment.

Injury | 2019 | Guerado E, Cano JR, Fernandez-Sanchez F

[Indexed for MEDLINE] 20. Rev Infect Dis. 1984 Nov-Dec;6 Suppl 4:S880-6. doi: 10.1093/clinids/6.supplement_4.s880. Antibiotic prophylaxis in surgery. Platt R. Perioperative prophylaxis accounts for a substantial proportion of antibiotic use in acute-care hospitals. There is clinical evidence of its efficacy in a number of circumstances. These include hysterectomy, cesarean deli...

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PubMed Narrative Review Evidence Moderate

Use of Intrawound Antibiotics in Orthopaedic Surgery.

The Journal of the American Academy of Orthopaedic Surgeons | 2018 | Chen AF, Fleischman A, Austin MS

[Indexed for MEDLINE] 19. Injury. 2019 Jun;50 Suppl 1:S45-S49. doi: 10.1016/j.injury.2019.03.044. Epub 2019 Apr 1. Pin tract infection prophylaxis and treatment. Guerado E(1), Cano JR(2), Fernandez-Sanchez F(3). Author information: (1)Department of Orthopaedic Surgery and Traumatology, Hospital Universitario Costa del Sol, University of Malaga, Marbella (Malaga), Spain. Electro...

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PubMed Narrative Review Evidence Moderate

Acute Management of Open Fractures: An Evidence-Based Review.

Orthopedics | 2015 | Halawi MJ, Morwood MP

[Indexed for MEDLINE] 6. Infect Dis Clin North Am. 2025 Sep;39(3):383-398. doi: 10.1016/j.idc.2025.02.016. Epub 2025 Apr 4. Preventing Orthopedic Infections. Ritter AS(1), Mears S(2). Author information: (1)Division of Infectious Diseases and Global Medicine, University of Florida, 2000 Southwest Archer Road, Gainesville, FL 32610, USA. Electronic address: Alaina.Ritter@medicin...

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PubMed Narrative Review Evidence Moderate

Infection in Orthopaedics.

Journal of orthopaedic trauma | 2015 | Cook GE, Markel DC, Ren W, Webb LX

[Indexed for MEDLINE] 8. Spine J. 2020 Mar;20(3):435-447. doi: 10.1016/j.spinee.2019.09.013. Epub 2019 Sep 23. Prophylactic postoperative measures to minimize surgical site infections in spine surgery: systematic review and evidence summary. Tan T(1), Lee H(1), Huang MS(2), Rutges J(3), Marion TE(4), Mathew J(5), Fitzgerald M(5), Gonzalvo A(6), Hunn MK(2), Kwon BK(7), Dvorak MF...

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PubMed Original Article Evidence Unclassified

Antibiotic prophylaxis in surgery for closed fracture of the hand.

Hand surgery & rehabilitation | 2024 | Lidauer K, Helenius I, Pääkkönen M

[Indexed for MEDLINE] 14. Orthopadie (Heidelb). 2025 Apr;54(4):253-260. doi: 10.1007/s00132-025-04611-0. Epub 2025 Feb 19. [Perioperative antibiotic prophylaxis in obesity]. [Article in German; Abstract available in German from the publisher] Schnurr C(1). Author information: (1)St. Vinzenz-Krankenhaus Düsseldorf, Schloßstraße 85, 40477, Düsseldorf, Deutschland. christoph.schnu...

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PubMed Narrative Review Evidence Moderate

Selfprotective smart orthopedic implants.

Expert review of medical devices | 2007 | Parvizi J, Antoci V Jr, Hickok NJ, Shapiro IM

[Indexed for MEDLINE] 16. Curr Drug Saf. 2023;18(1):116-120. doi: 10.2174/1574886317666220429081207. Antibiotic Prophylaxis for Orthopaedic Implant Removal: What Does the Evidence Say? Rather IIG(1), Shafiq N(1), Pandey AK(1), Bhandari RK(1), Malhotra S(1), Chouhan DK(2). Author information: (1)Department of Pharmacology, Post Graduate Institute of Medical Education and Researc...

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PubMed Narrative Review Evidence Moderate

Antibiotic prophylaxis in orthopedic prosthetic surgery.

Journal of chemotherapy (Florence, Italy) | 2001 | de Lalla F

[Indexed for MEDLINE] 18. J Am Acad Orthop Surg. 2018 Sep 1;26(17):e371-e378. doi: 10.5435/JAAOS-D-17-00003. Use of Intrawound Antibiotics in Orthopaedic Surgery. Chen AF(1), Fleischman A, Austin MS. Author information: (1)From the Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (Dr. Chen) and the Rothman Institute, Philadelph...

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Crossref Journal Article Evidence Unclassified

Antibiotic prophylaxis in veterinary orthopaedic surgery

Veterinary and Comparative Orthopaedics and Traumatology | 2001 | S. C. Budsberg, J. A. Kirsch

Antibiotic prophylaxis is widespread in veterinary and human surgery. Key principles must be followed in case selection, drug choice and administration to ensure maximal effectiveness. More prospective clinical trials in veterinary orthopaedics are needed to better define which patients and which procedures will benefit from antimicrobial prophylaxis.

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