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Evidence Search

Search reputable indexed orthopaedic literature from multiple scholarly sources, classify the evidence, and link papers directly to wiki topics and cases.

Sources: PubMed, Europe PMC, Crossref

Linking results to Wiki: Antibiotic Prophylaxis in Orthopaedics
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Results are classified automatically from source metadata across PubMed, Europe PMC, and Crossref.
PubMed Crossref
PubMed Guideline / Consensus Evidence High

AAOS Clinical Practice Guideline Summary Prevention of Total Hip and Knee Arthroplasty Periprosthetic Joint Infection in Patients Undergoing Dental Procedures.

The Journal of the American Academy of Orthopaedic Surgeons | 2025 | Hannon CP, Grosso MJ, Fillingham YA, Patton LL

[Indexed for MEDLINE] 10. Orthopadie (Heidelb). 2025 Apr;54(4):253-260. doi: 10.1007/s00132-025-04611-0. Epub 2025 Feb 19. [Perioperative antibiotic prophylaxis in obesity]. [Article in German; Abstract available in German from the publisher] Schnurr C(1). Author information: (1)St. Vinzenz-Krankenhaus Düsseldorf, Schloßstraße 85, 40477, Düsseldorf, Deutschland. christoph.schnu...

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PubMed Guideline / Consensus Evidence High

European Society of Clinical Microbiology and Infectious Diseases/European Committee on infection control clinical guidelines on pre-operative decolonization and targeted prophylaxis in patients colonized by multidrug-resistant Gram-positive bacteria befo

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases | 2024 | Righi E, Mutters NT, Guirao X, Dolores Del Toro M

[Indexed for MEDLINE] 5. J Orthop Trauma. 2015 Dec;29 Suppl 12:S19-23. doi: 10.1097/BOT.0000000000000461. Infection in Orthopaedics. Cook GE(1), Markel DC, Ren W, Webb LX, McKee MD, Schemitsch EH. Author information: (1)*Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, Canada; †Division of Orthopaedic Surgery, Department of Surgery, St....

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PubMed Guideline / Consensus Evidence High

Controversies in orthopaedic oncology.

The bone & joint journal | 2024 | Jeys LM, Thorkildsen J, Kurisunkal V, Puri A

[Indexed for MEDLINE] Conflict of interest statement: A. Puri is a member of the editorial board of The Bone & Joint Journal. P. Ruggieri reports consulting fees from Exactech and Stryker, unrelated to this study. M. T. Houdek reports consulting fees from Link Orthopedics, unrelated to this study. E. Botello reports consulting fees, payment or honoraria for lectures, presentati...

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PubMed Systematic Review / Meta-analysis Evidence High

Prophylactic postoperative measures to minimize surgical site infections in spine surgery: systematic review and evidence summary.

The spine journal : official journal of the North American Spine Society | 2020 | Tan T, Lee H, Huang MS, Rutges J

[Indexed for MEDLINE] 7. Bone Joint J. 2024 May 1;106-B(5):425-429. doi: 10.1302/0301-620X.106B5.BJJ-2023-1381. Controversies in orthopaedic oncology. Jeys LM(1), Thorkildsen J(2), Kurisunkal V(1), Puri A(3), Ruggieri P(4), Houdek MT(5), Boyle RA(6), Ebeid W(7), Botello E(8), Morris GV(1); BOOM Consensus Scientific Committee; Laitinen MK(140); BOOM Consensus Scientific Committe...

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PubMed Narrative Review Evidence Moderate

Optimizing Antibiotic Therapy in Musculoskeletal Infections.

Infectious disease clinics of North America | 2025 | Cortés-Penfield NW, Justo JA, McCreary EK, Ryder JH

[Indexed for MEDLINE] 4. Clin Microbiol Infect. 2024 Dec;30(12):1537-1550. doi: 10.1016/j.cmi.2024.07.012. Epub 2024 Aug 21. European Society of Clinical Microbiology and Infectious Diseases/European Committee on infection control clinical guidelines on pre-operative decolonization and targeted prophylaxis in patients colonized by multidrug-resistant Gram-positive bacteria befo...

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PubMed Narrative Review Evidence Moderate

Preventing Orthopedic Infections.

Infectious disease clinics of North America | 2025 | Ritter AS, Mears S

[Indexed for MEDLINE] Conflict of interest statement: Disclosure The authors have nothing to disclose. No funding source was used for this article. 9. J Am Acad Orthop Surg. 2025 Nov 1;33(21):e1260-e1267. doi: 10.5435/JAAOS-D-25-00458. Epub 2025 Jul 31. AAOS Clinical Practice Guideline Summary Prevention of Total Hip and Knee Arthroplasty Periprosthetic Joint Infection in Patie...

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PubMed Narrative Review Evidence Moderate

[Perioperative antibiotic prophylaxis in obesity].

Orthopadie (Heidelberg, Germany) | 2025 | Schnurr C

[Indexed for MEDLINE] Conflict of interest statement: Einhaltung ethischer Richtlinien. Interessenkonflikt: C. Schnurr gibt Beratertätigkeiten für Stryker und ZimmerBiomet an. Für diesen Beitrag wurden von den Autor/-innen keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien. 11. J Chemother....

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PubMed Narrative Review Evidence Moderate

Fracture related infection and sepsis in orthopedic trauma: A review.

Surgery | 2024 | Dvorak JE, Lasinski AM, Romeo NM, Hirschfeld A

[Indexed for MEDLINE] 18. Lakartidningen. 2019 Oct 21;116:FR6C. [Treatment of orthopedic implant-associated infections]. [Article in Swedish] Tevell S(1), Christensson B(2), Nilsdotter-Augustinsson Å(3), Rydén C(4), Ryding U(5), Söderquist B(6), Åkerlund B(7). Author information: (1)Infektionskliniken, Centralsjukhuset i Karlstad - Centrum för Klinisk Forskning, Region Värmland...

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PubMed Narrative Review Evidence Moderate

Overview of Antibiotic Prophylaxis in Orthopaedic and Cardiac Procedures.

Orthopedic nursing | 2023 | Karapetyan K, Mei S, Choudhury A, Cottreau J

[Indexed for MEDLINE] Conflict of interest statement: The authors have no known conflicts of interest to disclose. 15. Rev Infect Dis. 1984 Nov-Dec;6 Suppl 4:S880-6. doi: 10.1093/clinids/6.supplement_4.s880. Antibiotic prophylaxis in surgery. Platt R. Perioperative prophylaxis accounts for a substantial proportion of antibiotic use in acute-care hospitals. There is clinical evi...

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PubMed Narrative Review Evidence Moderate

Antibiotic prophylaxis in orthopedics-traumatology.

Orthopaedics & traumatology, surgery & research : OTSR | 2021 | Gaudias J

[Indexed for MEDLINE] 2. J Am Acad Orthop Surg. 2020 Apr 15;28(8):309-315. doi: 10.5435/JAAOS-D-18-00193. Antibiotic Prophylaxis in Open Fractures: Evidence, Evolving Issues, and Recommendations. Garner MR(1), Sethuraman SA, Schade MA, Boateng H. Author information: (1)From the Department of Orthopaedic Trauma (Dr. Garner, Dr. Boateng), Penn State College of Medicine, Milton S....

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PubMed Narrative Review Evidence Moderate

Antibiotic Prophylaxis in Open Fractures: Evidence, Evolving Issues, and Recommendations.

The Journal of the American Academy of Orthopaedic Surgeons | 2020 | Garner MR, Sethuraman SA, Schade MA, Boateng H

[Indexed for MEDLINE] 3. Infect Dis Clin North Am. 2025 Sep;39(3):361-382. doi: 10.1016/j.idc.2025.02.009. Epub 2025 Apr 11. Optimizing Antibiotic Therapy in Musculoskeletal Infections. Cortés-Penfield NW(1), Justo JA(2), McCreary EK(3), Ryder JH(4). Author information: (1)Division of Infectious Diseases, University of Nebraska Medical Center, Omaha, NE, USA. Electronic address...

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PubMed Narrative Review Evidence Moderate

Gunshot Wounds to the Upper Extremity.

The Journal of the American Academy of Orthopaedic Surgeons | 2019 | Omid R, Stone MA, Zalavras CG, Marecek GS

[Indexed for MEDLINE] 17. Surgery. 2024 Aug;176(2):535-540. doi: 10.1016/j.surg.2024.04.031. Epub 2024 Jun 1. Fracture related infection and sepsis in orthopedic trauma: A review. Dvorak JE(1), Lasinski AM(2), Romeo NM(3), Hirschfeld A(3), Claridge JA(2). Author information: (1)Department of Surgery, Division of Trauma, MetroHealth Medical Center, Cleveland, OH, Case Western Re...

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PubMed Narrative Review Evidence Moderate

[Treatment of orthopedic implant-associated infections].

Lakartidningen | 2019 | Tevell S, Christensson B, Nilsdotter-Augustinsson Å, Rydén C

[Indexed for MEDLINE] 19. Rev Infect Dis. 1991 Sep-Oct;13 Suppl 10:S842-6. doi: 10.1093/clinids/13.supplement_10.s842. Antibiotic prophylaxis in orthopedic surgery. Norden CW(1). Author information: (1)Department of Medicine, Montefiore Hospital, University of Pittsburgh School of Medicine, Pennsylvania. This review covers four areas: the use of prophylactic antibiotics in orth...

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PubMed Narrative Review Evidence Moderate

Infection in Orthopaedics.

Journal of orthopaedic trauma | 2015 | Cook GE, Markel DC, Ren W, Webb LX

[Indexed for MEDLINE] 6. Spine J. 2020 Mar;20(3):435-447. doi: 10.1016/j.spinee.2019.09.013. Epub 2019 Sep 23. Prophylactic postoperative measures to minimize surgical site infections in spine surgery: systematic review and evidence summary. Tan T(1), Lee H(1), Huang MS(2), Rutges J(3), Marion TE(4), Mathew J(5), Fitzgerald M(5), Gonzalvo A(6), Hunn MK(2), Kwon BK(7), Dvorak MF...

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PubMed Narrative Review Evidence Moderate

Prophylactic antibiotics in orthopaedic surgery.

The Journal of the American Academy of Orthopaedic Surgeons | 2008 | Prokuski L

[Indexed for MEDLINE] 13. Expert Rev Med Devices. 2007 Jan;4(1):55-64. doi: 10.1586/17434440.4.1.55. Selfprotective smart orthopedic implants. Parvizi J(1), Antoci V Jr, Hickok NJ, Shapiro IM. Author information: (1)Thomas Jefferson University, Rothman Institute of Orthopedics, 925 Chestnut Street, Philadelphia, PA 19107, USA. parvj@aol.com In this review, we discuss current ad...

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PubMed Narrative Review Evidence Moderate

Selfprotective smart orthopedic implants.

Expert review of medical devices | 2007 | Parvizi J, Antoci V Jr, Hickok NJ, Shapiro IM

[Indexed for MEDLINE] 14. Orthop Nurs. 2023 Sep-Oct 01;42(5):312-316. doi: 10.1097/NOR.0000000000000972. Overview of Antibiotic Prophylaxis in Orthopaedic and Cardiac Procedures. Karapetyan K(1)(2)(3)(4), Mei S(1)(2)(3)(4), Choudhury A(1)(2)(3)(4), Cottreau J(1)(2)(3)(4). Author information: (1)Kristina Karapetyan, PharmD, PGY-2 Ambulatory Care Pharmacy Resident, Captain James...

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PubMed Narrative Review Evidence Moderate

Antibiotic prophylaxis in orthopedic prosthetic surgery.

Journal of chemotherapy (Florence, Italy) | 2001 | de Lalla F

[Indexed for MEDLINE] 12. J Am Acad Orthop Surg. 2008 May;16(5):283-93. doi: 10.5435/00124635-200805000-00007. Prophylactic antibiotics in orthopaedic surgery. Prokuski L(1). Author information: (1)University of Wisconsin Hospitals, Madison, WI 53792, USA. The use of prophylactic antibiotics in orthopaedic surgery is effective in reducing surgical site infections in hip and kne...

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PubMed Narrative Review Evidence Moderate

Antibiotic prophylaxis in orthopedic surgery.

Reviews of infectious diseases | 1991 | Norden CW

[Indexed for MEDLINE] 20. Curr Drug Saf. 2023;18(1):116-120. doi: 10.2174/1574886317666220429081207. Antibiotic Prophylaxis for Orthopaedic Implant Removal: What Does the Evidence Say? Rather IIG(1), Shafiq N(1), Pandey AK(1), Bhandari RK(1), Malhotra S(1), Chouhan DK(2). Author information: (1)Department of Pharmacology, Post Graduate Institute of Medical Education and Researc...

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Crossref Journal Article Evidence Unclassified

Antibiotic prophylaxis in veterinary orthopaedic surgery

Veterinary and Comparative Orthopaedics and Traumatology | 2001 | S. C. Budsberg, J. A. Kirsch

Antibiotic prophylaxis is widespread in veterinary and human surgery. Key principles must be followed in case selection, drug choice and administration to ensure maximal effectiveness. More prospective clinical trials in veterinary orthopaedics are needed to better define which patients and which procedures will benefit from antimicrobial prophylaxis.

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PubMed Narrative Review Evidence Moderate

Antibiotic prophylaxis in surgery.

Reviews of infectious diseases | 1984 | Platt R

[Indexed for MEDLINE] 16. J Am Acad Orthop Surg. 2019 Apr 1;27(7):e301-e310. doi: 10.5435/JAAOS-D-17-00676. Gunshot Wounds to the Upper Extremity. Omid R(1), Stone MA, Zalavras CG, Marecek GS. Author information: (1)From the Department of Orthopaedic Surgery, University of Southern California, Keck School of Medicine, Los Angeles, CA. Upper extremity gunshot wounds result in no...

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