Failure of mineralization at the growth plate → metaphyseal cupping, fraying, and splaying with genu varum/valgum. Differentiate **nutritional vitamin D deficiency** from **X‑linked hypophosphatemic rickets (XLH)** and renal rickets; labs guide diagnosis. Medical therapy first: vitamin D and calcium for nutritional; **phosphate + active vitamin D** (calcitriol) for XLH; burosumab in select cases. Orthopaedic: guided growth hemiepiphysiodesis for coronal deformity; corrective osteotomy when severe/rigid or after metabolic control. Beware Looser zones (pseudofractures) and bone pain; correct biochemistry pre‑op to improve healing.
In X-linked hypophosphatemic rickets (XLH), which biochemical finding is typically observed?
What is the primary medical treatment for nutritional rickets?
Which radiographic sign is characteristic of active rickets?
What is the distinguishing biochemical feature of X-linked hypophosphatemic rickets compared to nutritional rickets?
What surgical intervention is indicated for severe, rigid coronal deformities associated with rickets?
What is the most common orthopedic sequelae of rickets?
Which condition is characterized by pseudofractures or Looser zones in adults?
Which of the following is true regarding the treatment of X-linked hypophosphatemic rickets?
What preoperative biochemical correction is important for improving healing in rickets patients undergoing surgery?
Which of the following is the most common cause of rickets worldwide?
