Evidence Search

The Diagnosis and Treatment of Acetabular Bone Loss in Revision Hip Arthroplasty: An International Consensus Symposium.

HSS journal : the musculoskeletal journal of Hospital for Special Surgery | 2022 | Sculco PK, Wright T, Malahias MA, Gu A

Conflict of interest statement: Declaration of Conflicting Interests: The author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: Peter K. Sculco, MD, reports relationships with EOS Imaging, DePuy Synthes, Intellijoint Surgical, and Parvizi Surgical Innovation. Timothy Wright, PhD, reports re...

Combined direct anterior approach and navigation-assisted percutaneous anterograde posterior column fixation for acetabular periprosthetic fractures.

Operative Orthopadie und Traumatologie | 2026 | Beckers G, Simon D, Lerchenberger M, Böcker W

[Indexed for MEDLINE] Conflict of interest statement: Declarations. Conflict of interest: G. Beckers, D. Simon, M. Lerchenberger, W. Böcker, J. Arnholdt, and B.M. Holzapfel declare that they have no competing interests. For this article no studies with human participants or animals were performed by any of the authors. All studies mentioned were in accordance with the ethical s...

Catastrophic Periprosthetic Osteolysis in Total Hip Arthroplasty at 20 Years: A Case Report and Literature Review

Orthopaedic Surgery | 2022 | Dan Xing, Rujun Li, Jiao Jiao Li, Ke Tao

BackgroundPeriprosthetic osteolysis is a serious complication following total hip arthroplasty (THA). However, most orthopedic surgeons only focus on bone loss and hip reconstruction. Thus, it was required to understand the treatment algorithm for periprosthetic osteolysis integrally.Case PresentationA 52‐year‐old Asian male presented with chronic hip pain. A mass appeared on t...

Diagnosis and management of implant debris-associated inflammation.

Expert review of medical devices | 2020 | Goodman SB, Gallo J, Gibon E, Takagi M

[Indexed for MEDLINE] Conflict of interest statement: Declaration of interest The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert...

Bone Defects in Revision Total Knee Arthroplasty and Management.

Orthopaedic surgery | 2019 | Lei PF, Hu RY, Hu YH

[Indexed for MEDLINE] 3. J Nanobiotechnology. 2023 Oct 31;21(1):398. doi: 10.1186/s12951-023-02177-7. PLGA nanoparticles engineering extracellular vesicles from human umbilical cord mesenchymal stem cells ameliorates polyethylene particles induced periprosthetic osteolysis. Xie J(1), Hu Y(1), Su W(2), Chen S(3), Wang J(4), Liang S(4), Chen M(3), Wang H(4), Ma T(5). Author infor...

What are the guidelines for the surgical and nonsurgical treatment of periprosthetic osteolysis?

The Journal of the American Academy of Orthopaedic Surgeons | 2008 | Stulberg BN, Della Valle AG, Implant Wear Symposium 2007 Clinical Work Group

[Indexed for MEDLINE] 18. Am J Orthop (Belle Mead NJ). 2002 Apr;31(4):221-3. Periprosthetic fractures of the femur following hip arthroplasty. Nelson CL(1). Author information: (1)Department of Orthopedic Surgery, University of Pennsylvania Medical Center, Philadelphia, USA. Periprosthetic femoral fractures are one of the leading causes of revision total hip arthroplasty. Risk...

MR Imaging of Knee Arthroplasty Implants.

Radiographics : a review publication of the Radiological Society of North America, Inc | 2015 | Fritz J, Lurie B, Potter HG

[Indexed for MEDLINE] 5. Inflammopharmacology. 2013 Dec;21(6):389-96. doi: 10.1007/s10787-013-0192-6. Epub 2013 Oct 15. Periprosthetic osteolysis after total hip replacement: molecular pathology and clinical management. Howie DW(1), Neale SD, Haynes DR, Holubowycz OT, McGee MA, Solomon LB, Callary SA, Atkins GJ, Findlay DM. Author information: (1)Department of Orthopaedics and...

Functional and radiological outcome of periprosthetic femoral fractures after hip arthroplasty.

Injury | 2015 | Moreta J, Aguirre U, de Ugarte OS, Jáuregui I

[Indexed for MEDLINE] 9. HSS J. 2022 Feb;18(1):8-41. doi: 10.1177/15563316211034850. Epub 2021 Sep 28. The Diagnosis and Treatment of Acetabular Bone Loss in Revision Hip Arthroplasty: An International Consensus Symposium. Sculco PK(1), Wright T(1), Malahias MA(1), Gu A(2), Bostrom M(1), Haddad F(3), Jerabek S(1), Bolognesi M(4), Fehring T(5), Gonzalez DellaValle A(1), Jiranek...

Periprosthetic osteolysis after total hip replacement: molecular pathology and clinical management.

Inflammopharmacology | 2013 | Howie DW, Neale SD, Haynes DR, Holubowycz OT

[Indexed for MEDLINE] 6. J Bone Joint Surg Am. 2025 Apr 16;107(8):e33. doi: 10.2106/JBJS.24.00580. Epub 2025 Feb 25. Outcomes of Autogenous Bone Grafting for Periprosthetic Osteolysis After Total Ankle Arthroplasty: Clinical and 3-Dimensional Computed Tomography Results. Yoon YK(1), Park KH(2), Shim DW(2), Lee W(2), Chae JS(3), Han SH(4), Lee JW(2). Author information: (1)Depar...

Femoral bone loss in revision total hip arthroplasty: evaluation and management.

The Journal of the American Academy of Orthopaedic Surgeons | 2013 | Sheth NP, Nelson CL, Paprosky WG

[Indexed for MEDLINE] 11. Orthop Traumatol Surg Res. 2020 May;106(3):449-458. doi: 10.1016/j.otsr.2020.01.008. Epub 2020 Mar 14. Management and results in periprosthetic tibial fracture after total knee arthroplasty: Two-center 15-case retrospective series at 2 years' follow-up. Bauer C(1), Zaharia B(2), Galliot F(2), Parot J(2), Houfani F(2), Mayer J(3), Mainard D(2). Author i...

Review of periprosthetic osteolysis in total joint arthroplasty: An emphasis on host factors and future directions

Journal of Orthopaedic Research | 2012 | Ryan T. Beck, Kenneth D. Illingworth, Khaled J. Saleh

AbstractPeriprosthetic osteolysis is one of the leading causes of total joint revision procedures. If allowed to progress in the absence of radiographic diagnosis and/or proper medical treatment, osteolysis may result in aseptic loosening yielding failure of the implant and the need for complex revision arthroplasty. The purpose of this review was to assess the current understa...

Outcomes of Autogenous Bone Grafting for Periprosthetic Osteolysis After Total Ankle Arthroplasty: Clinical and 3-Dimensional Computed Tomography Results.

The Journal of bone and joint surgery. American volume | 2025 | Yoon YK, Park KH, Shim DW, Lee W

[Indexed for MEDLINE] Conflict of interest statement: Disclosure: This study was supported by a faculty research grant from Yonsei University College of Medicine (6-2022-0167) and by the Korea Institute for Advancement of Technology grant funded by the Government of the Republic of Korea (Ministry of Trade, Industry and Energy; no. P0013646).The Disclosure of Potential Conflict...

Radial head replacement with periprosthetic osteolysis

Radiopaedia.org | 2025 | Rory Weir

Metallosis in Total Hip Arthroplasty.

JBJS reviews | 2023 | Lee A, Paiement GD, Penenberg BL, Rajaee SS

[Indexed for MEDLINE] Conflict of interest statement: Disclosure: The Disclosure of Potential Conflicts of Interest forms are provided with the online version of the article (http://links.lww.com/JBJSREV/B15). 2. Orthop Surg. 2019 Feb;11(1):15-24. doi: 10.1111/os.12425. Epub 2019 Feb 27. Bone Defects in Revision Total Knee Arthroplasty and Management. Lei PF(1), Hu RY(2), Hu YH...

PLGA nanoparticles engineering extracellular vesicles from human umbilical cord mesenchymal stem cells ameliorates polyethylene particles induced periprosthetic osteolysis.

Journal of nanobiotechnology | 2023 | Xie J, Hu Y, Su W, Chen S

[Indexed for MEDLINE] Conflict of interest statement: All other authors declare no competing interests. 4. Radiographics. 2015 Sep-Oct;35(5):1483-501. doi: 10.1148/rg.2015140216. Epub 2015 Aug 21. MR Imaging of Knee Arthroplasty Implants. Fritz J(1), Lurie B(1), Potter HG(1). Author information: (1)From the Department of Radiology and Imaging, Hospital for Special Surgery, 535...

Diagnostic Performance of Dual-Energy CT for Detecting Painful Hip Prosthesis Loosening.

Radiology | 2021 | Foti G, Fighera A, Campacci A, Natali S

[Indexed for MEDLINE] 20. Oper Orthop Traumatol. 2026 Apr;38(2):104-118. doi: 10.1007/s00064-025-00900-1. Epub 2025 May 7. Combined direct anterior approach and navigation-assisted percutaneous anterograde posterior column fixation for acetabular periprosthetic fractures. [Article in English] Beckers G(1), Simon D(1), Lerchenberger M(1), Böcker W(1), Arnholdt J(1), Holzapfel BM...

Management and results in periprosthetic tibial fracture after total knee arthroplasty: Two-center 15-case retrospective series at 2 years' follow-up.

Orthopaedics & traumatology, surgery & research : OTSR | 2020 | Bauer C, Zaharia B, Galliot F, Parot J

[Indexed for MEDLINE] 12. J Arthroplasty. 1998 Oct;13(7):843-5. doi: 10.1016/s0883-5403(98)90042-0. Periprosthetic acetabular fracture associated with extensive osteolysis. Chatoo M(1), Parfitt J, Pearse MF. Author information: (1)Department of Orthopaedic Surgery, Central Middlesex Hospital, London, United Kingdom. Periprosthetic fracture of the acetabulum is an uncommon compl...

Novel in vivo mouse model of shoulder implant infection.

Journal of shoulder and elbow surgery | 2020 | Sheppard WL, Mosich GM, Smith RA, Hamad CD

[Indexed for MEDLINE] 14. Eur J Orthop Surg Traumatol. 2018 Jan;28(1):37-43. doi: 10.1007/s00590-017-2010-0. Epub 2017 Jun 28. Adventure sports and sexual freedom hip replacement: the tripolar hip. Pritchett JW(1). Author information: (1), 901 Boren Ave #900, Seattle, WA, 98104, USA. bonerecon@aol.com. Certain athletic activities and lifestyles require a completely stable and v...

Adventure sports and sexual freedom hip replacement: the tripolar hip.

European journal of orthopaedic surgery & traumatology : orthopedie traumatologie | 2018 | Pritchett JW

[Indexed for MEDLINE] 15. Eur J Radiol. 2011 Jan;77(1):43-50. doi: 10.1016/j.ejrad.2010.08.015. Epub 2010 Oct 8. Severe osteolysis and soft tissue mass around total hip arthroplasty: description of four cases and review of the literature with respect to clinico-radiographic and pathologic differential diagnosis. Fabbri N(1), Rustemi E, Masetti C, Kreshak J, Gambarotti M, Vanel...

Metal artifact reduction MRI of total ankle arthroplasty implants.

European radiology | 2018 | de Cesar Netto C, Fonseca LF, Fritz B, Stern SE

[Indexed for MEDLINE] 17. J Am Acad Orthop Surg. 2008;16 Suppl 1:S20-5. doi: 10.5435/00124635-200800001-00006. What are the guidelines for the surgical and nonsurgical treatment of periprosthetic osteolysis? Stulberg BN(1), Della Valle AG; Implant Wear Symposium 2007 Clinical Work Group. Collaborators: Callaghan JJ, Cuckler JM, Galante JO, Della Valle AG, Goodman SB, Huddleston...

Periprosthetic fractures of the femur following hip arthroplasty.

American journal of orthopedics (Belle Mead, N.J.) | 2002 | Nelson CL

[Indexed for MEDLINE] 19. Radiology. 2021 Sep;300(3):641-649. doi: 10.1148/radiol.2021203510. Epub 2021 Jul 6. Diagnostic Performance of Dual-Energy CT for Detecting Painful Hip Prosthesis Loosening. Foti G(1), Fighera A(1), Campacci A(1), Natali S(1), Guerriero M(1), Zorzi C(1), Carbognin G(1). Author information: (1)From the Departments of Radiology (G.F., G.C.) and Orthopaed...

Management of Periprosthetic Fractures

Orthopaedic Knowledge Online Journal | 2017

Severe osteolysis and soft tissue mass around total hip arthroplasty: description of four cases and review of the literature with respect to clinico-radiographic and pathologic differential diagnosis.

European journal of radiology | 2011 | Fabbri N, Rustemi E, Masetti C, Kreshak J

[Indexed for MEDLINE] 16. Eur Radiol. 2018 May;28(5):2216-2227. doi: 10.1007/s00330-017-5153-9. Epub 2017 Dec 7. Metal artifact reduction MRI of total ankle arthroplasty implants. de Cesar Netto C(1)(2), Fonseca LF(1), Fritz B(3)(4), Stern SE(5), Raithel E(6), Nittka M(6), Schon LC(1), Fritz J(7). Author information: (1)Department of Orthopedic Surgery, MedStar Union Memorial H...

Periprosthetic Osteolysis of Total Hip Arthroplasties (THA)

Trauma and Orthopaedic Classifications | 2015 | Nikolaos K. Kanakaris, Peter V. Giannoudis

Acetabular fracture, osteolysis, and loose cup

Periprosthetic Fracture Management | 2013

What Is the Best Method to Image Periprosthetic Osteolysis Around Total Knee Arthroplasties?

JBJS Orthopaedic Highlights: Knee Surgery | 2012 | Michael A. Mont

Underappreciated benefits of erythromycin in the management of periprosthetic inflammation and osteolysis

Bone | 2010 | W. Ren, R.B. Blasier, D.C. Markel

Magnetic resonance imaging in the evaluation of periprosthetic acetabular osteolysis: A cadaveric study

Journal of Orthopaedic Research | 2005 | Daniel E. Weiland, Tim A. Walde, Serena B. Leung, Christi J. Sychterz

AbstractPeriprosthetic osteolysis is a well recognized complication of total hip arthroplasty that leads to implant failure. The ability to accurately assess and visualize the position and volume of periacetabular bone defects is paramount for clinical observation and medical treatment, as well as pre‐operative planning of revision surgery. We have developed a modified magnetic...

Periprosthetic acetabular fracture associated with extensive osteolysis.

The Journal of arthroplasty | 1998 | Chatoo M, Parfitt J, Pearse MF

[Indexed for MEDLINE] 13. J Shoulder Elbow Surg. 2020 Jul;29(7):1412-1424. doi: 10.1016/j.jse.2019.10.032. Epub 2020 Jan 31. Novel in vivo mouse model of shoulder implant infection. Sheppard WL(1), Mosich GM(2), Smith RA(3), Hamad CD(2), Park HY(2), Zoller SD(2), Trikha R(1), McCoy TK(3), Borthwell R(3), Hoang J(3), Truong N(3), Cevallos N(3), Clarkson S(3), Hori KR(3), van Dij...

Two distinct cellular mechanisms of osteoclast formation and bone resorption in periprosthetic osteolysis

Journal of Orthopaedic Research | 2003 | A. Sabokbar, O. Kudo, N. A. Athanasou

AbstractPurpose: TNFα and IL‐1α are proinflammatory cytokines that are abundant in periprosthetic tissues. These cytokines stimulate bone resorption and have recently been shown to directly induce osteoclast formation in mouse marrow cultures. We examined whether TNFα and IL‐1α can directly induce osteoclast formation from human arthroplasty‐derived (CD14+) macrophages by a mec...

Erratum to “Pressure‐induced periprosthetic osteolysis: a rat model”

Journal of Orthopaedic Research | 2002 | Ralf Skripitz, Per Aspenberg

Pressure‐induced periprosthetic osteolysis: A rat model

Journal of Orthopaedic Research | 2000 | Ralf Skripitz, Per Aspenberg

AbstractRecent animal experiments have indicated that oscillating fluid pressure at the interface of bone and implant can lead to osteolysis. However, external nonphysiologic saline solutions were used to generate the pressure in these studies. In the present study on 15 Sprague‐Dawley rats, hydrostatic pressure fluctuations were applied to bone through body fluids, by compress...

Periprosthetic osteolysis

SpringerReference

Periprosthetic osteolysis

Rheumatology and Immunology Therapy