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Evidence Search

Search reputable indexed orthopaedic literature from multiple scholarly sources, classify the evidence, and link papers directly to wiki topics and cases.

Sources: PubMed, Europe PMC, Crossref

Linking results to Wiki: Ewing’s Sarcoma — Protocols
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Results are classified automatically from source metadata across PubMed, Europe PMC, and Crossref.
PubMed Crossref
PubMed Guideline / Consensus Evidence High

Consensus recommendations for systemic therapies in the management of relapsed Ewing sarcoma: A report from the National Ewing Sarcoma Tumor Board.

Cancer | 2024 | Gupta A, Dietz MS, Riedel RF, Dhir A

[Indexed for MEDLINE] 6. Nat Rev Dis Primers. 2022 Oct 6;8(1):66. doi: 10.1038/s41572-022-00393-3. Small round cell sarcomas. Cidre-Aranaz F(1)(2), Watson S(3)(4), Amatruda JF(5)(6), Nakamura T(7), Delattre O(4), de Alava E(8)(9), Dirksen U(10), Grünewald TGP(11)(12)(13). Author information: (1)Division of Translational Paediatric Sarcoma Research, German Cancer Research Center...

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PubMed Guideline / Consensus Evidence High

Consensus recommendations in the management of Ewing sarcoma from the National Ewing Sarcoma Tumor Board.

Cancer | 2023 | Gupta A, Riedel RF, Shah C, Borinstein SC

[Indexed for MEDLINE] 2. N Engl J Med. 2003 Feb 20;348(8):694-701. doi: 10.1056/NEJMoa020890. Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone. Grier HE(1), Krailo MD, Tarbell NJ, Link MP, Fryer CJ, Pritchard DJ, Gebhardt MC, Dickman PS, Perlman EJ, Meyers PA, Donaldson SS, Moore S, Rausen AR, Vietti T...

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PubMed Randomized Controlled Trial Evidence High

Comparison of two chemotherapy regimens in patients with newly diagnosed Ewing sarcoma (EE2012): an open-label, randomised, phase 3 trial.

Lancet (London, England) | 2022 | Brennan B, Kirton L, Marec-Bérard P, Gaspar N

[Indexed for MEDLINE] Conflict of interest statement: Declaration of interests SS has received honoraria and consulting fees from GSK, Lilly, and Ceridwen Oncology. JM-B reports institutional grants from Adaptimmune, Amgen, AROG, Bayer, Blueprint, Bristol Myers Squibb, Celgene, Daichii-Sankyo, Deciphera, Eisai, FORMA, GSK, IMMIX Biopharma, Karyopharm, Lilly, Nektar, Novartis, P...

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PubMed Randomized Controlled Trial Evidence High

High-Dose Treosulfan and Melphalan as Consolidation Therapy Versus Standard Therapy for High-Risk (Metastatic) Ewing Sarcoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology | 2022 | Koch R, Gelderblom H, Haveman L, Brichard B

[Indexed for MEDLINE] 11. J Surg Oncol. 1993 Mar;52(3):188-92. doi: 10.1002/jso.2930520315. Ewing's sarcoma. Iyer RS(1), Rao SR, Gurjal A, Nair CN, Pai SK, Kurkure PA, Pande SC, Advani SH. Author information: (1)Department of Medical Oncology, Tata Memorial Hospital, Bombay, India. Between 1984-1987, 50 patients with Ewing's sarcoma of the bone were entered on combined modality...

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PubMed Randomized Controlled Trial Evidence High

Phase III Trial Adding Vincristine-Topotecan-Cyclophosphamide to the Initial Treatment of Patients With Nonmetastatic Ewing Sarcoma: A Children's Oncology Group Report.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology | 2021 | Leavey PJ, Laack NN, Krailo MD, Buxton A

[Indexed for MEDLINE] Conflict of interest statement: Patrick J. LeaveyResearch Funding: Eleison Pharmaceuticals Nadia N. LaackResearch Funding: Bristol Myers Squib Mark D. KrailoConsulting or Advisory Role: Merck Sharp & DohmeTravel, Accommodations, Expenses: Merck Sharp & Dohme R. Lor RandallHonoraria: Daiichi Sankyo, Onkos Surgical, OncliveTravel, Accommodations, Expenses: B...

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PubMed Narrative Review Evidence Moderate

Small round cell sarcomas.

Nature reviews. Disease primers | 2022 | Cidre-Aranaz F, Watson S, Amatruda JF, Nakamura T

[Indexed for MEDLINE] 7. Gan To Kagaku Ryoho. 2007 Feb;34(2):175-80. [Ewing sarcoma]. [Article in Japanese] Hamanoue S(1), Makimoto A. Author information: (1)Division of Pediatrics, National Cancer Center Hospital. Ewing sarcoma is the second most frequent primary bone cancer affecting children or young adults. Advances in molecular biology have revealed common chromosomal tran...

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PubMed Narrative Review Evidence Moderate

Advances in immune checkpoint inhibitors for bone sarcoma therapy.

Journal of bone oncology | 2019 | Thanindratarn P, Dean DC, Nelson SD, Hornicek FJ

18. Ochsner J. 2024 Fall;24(3):213-218. doi: 10.31486/toj.24.0014. Recurrent Intracranial Ewing Sarcoma. Yap SA(1)(2)(3), Alig AHS(1), Hasenburg AA(1), Hilfenhaus G(1), Stephan LU(1), Pelzer U(1), Stintzing S(1)(3), Stahler A(1). Author information: (1)Department of Hematology, Oncology and Cancer Immunology, Charité Universitätsmedizin, Berlin, Germany. (2)Department of Hemato...

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PubMed Case Report / Series Evidence Low

Recurrent Intracranial Ewing Sarcoma.

Ochsner journal | 2024 | Yap SA, Alig AHS, Hasenburg AA, Hilfenhaus G

19. J Clin Oncol. 1995 Jul;13(7):1786-99. doi: 10.1200/JCO.1995.13.7.1786. High-dose intravenous melphalan: a review. Samuels BL(1), Bitran JD. Author information: (1)Department of Medicine, Lutheran General Hospital, University of Chicago School of Medicine, Park Ridge, IL, USA. PURPOSE: To review the clinical pharmacology and clinical trials that have used intravenous (IV) hi...

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PubMed Randomized Controlled Trial Evidence High

Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone.

The New England journal of medicine | 2003 | Grier HE, Krailo MD, Tarbell NJ, Link MP

[Indexed for MEDLINE] 3. Lancet. 2022 Oct 29;400(10362):1513-1521. doi: 10.1016/S0140-6736(22)01790-1. Comparison of two chemotherapy regimens in patients with newly diagnosed Ewing sarcoma (EE2012): an open-label, randomised, phase 3 trial. Brennan B(1), Kirton L(2), Marec-Bérard P(3), Gaspar N(4), Laurence V(5), Martín-Broto J(6), Sastre A(7), Gelderblom H(8), Owens C(9), Fen...

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PubMed Narrative Review Evidence Moderate

Ewing's sarcoma.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists | 2010 | Karosas AO

[Indexed for MEDLINE] 5. Cancer. 2024 Dec 1;130(23):4028-4039. doi: 10.1002/cncr.35537. Epub 2024 Aug 25. Consensus recommendations for systemic therapies in the management of relapsed Ewing sarcoma: A report from the National Ewing Sarcoma Tumor Board. Gupta A(1)(2), Dietz MS(3), Riedel RF(4), Dhir A(5), Borinstein SC(6), Isakoff MS(7), Aye JM(8), Rainusso N(9), Armstrong AE(1...

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PubMed Narrative Review Evidence Moderate

Sarcoma and the spinal column.

Neurosurgery clinics of North America | 2008 | Wang VY, Potts M, Chou D

[Indexed for MEDLINE] 13. Curr Protoc. 2023 Feb;3(2):e670. doi: 10.1002/cpz1.670. Modeling Ewing Sarcoma Lung Metastasis. Dasgupta A(1), Kurenbekova L(1), Patel TD(1), Rajapakshe K(2), Ghosal G(3), Nirala B(1), Coarfa C(4)(5), Yustein J(1). Author information: (1)Texas Children's Cancer and Hematology Centers and The Faris D. Virani Ewing Sarcoma Center, Baylor College of Medic...

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PubMed Original Article Evidence Unclassified

Modeling Ewing Sarcoma Lung Metastasis.

Current protocols | 2023 | Dasgupta A, Kurenbekova L, Patel TD, Rajapakshe K

[Indexed for MEDLINE] Conflict of interest statement: CONFLICT OF INTEREST STATEMENT: No conflict of interest to declare. 14. Cancer. 1999 Feb 1;85(3):725-31. Extraskeletal Ewing's sarcoma. Ahmad R(1), Mayol BR, Davis M, Rougraff BT. Author information: (1)Department of Orthopaedics, Indiana University School of Medicine, Indianapolis 46202, USA. BACKGROUND: Ewing's sarcoma usu...

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PubMed Original Article Evidence Unclassified

Ewing sarcoma during follow-up.

Nuklearmedizin. Nuclear medicine | 2017 | Heinemann M, Ranft A, Jürgens H, Langer T

[Indexed for MEDLINE] Conflict of interest statement: The authors have nothing to disclose.

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PubMed Narrative Review Evidence Moderate

High-dose intravenous melphalan: a review.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology | 1995 | Samuels BL, Bitran JD

[Indexed for MEDLINE] 20. Nuklearmedizin. 2017;56(6):233-238. doi: 10.3413/Nukmed-0909-17-07. Epub 2018 Jan 11. Ewing sarcoma during follow-up. [Article in English] Heinemann M, Ranft A, Jürgens H, Langer T, Vieth V, Timmermann B, Weckesser M, Dirksen U, Stegger L. AIM: To evaluate the performance of a prospectively defined follow-up imaging protocol that includes FDG-PET(/CT)...

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PubMed Narrative Review Evidence Moderate

[Therapy of Ewing's sarcoma].

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] | 1993 | Dunst J, Sauer R

[Indexed for MEDLINE] 16. Pediatr Med Chir. 1984 Mar-Apr;6(2):201-8. [Bone tumors]. [Article in Italian] Madon E, Grazia G, Brach Del Prever A. In this paper are briefly reasumed clinical features and diagnostic procedures for bone tumors. More closely are examinated osteogenic sarcoma and Ewing's sarcoma in childhood and evaluated therapeutical means comparing the achieved res...

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PubMed Original Article Evidence Unclassified

[Ewing sarcoma].

Gan to kagaku ryoho. Cancer & chemotherapy | 2007 | Hamanoue S, Makimoto A

[Indexed for MEDLINE] 8. J Clin Oncol. 2021 Dec 20;39(36):4029-4038. doi: 10.1200/JCO.21.00358. Epub 2021 Oct 15. Phase III Trial Adding Vincristine-Topotecan-Cyclophosphamide to the Initial Treatment of Patients With Nonmetastatic Ewing Sarcoma: A Children's Oncology Group Report. Leavey PJ(1), Laack NN(2), Krailo MD(3), Buxton A(4), Randall RL(5), DuBois SG(6), Reed DR(7), Gr...

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PubMed Original Article Evidence Unclassified

[Ewing's sarcoma].

Gan to kagaku ryoho. Cancer & chemotherapy | 2004 | Goto T, Hozumi T, Kondo T

[Indexed for MEDLINE] 10. J Clin Oncol. 2022 Jul 20;40(21):2307-2320. doi: 10.1200/JCO.21.01942. Epub 2022 Apr 15. High-Dose Treosulfan and Melphalan as Consolidation Therapy Versus Standard Therapy for High-Risk (Metastatic) Ewing Sarcoma. Koch R(1), Gelderblom H(2), Haveman L(3), Brichard B(4), Jürgens H(5), Cyprova S(6), van den Berg H(7), Hassenpflug W(8), Raciborska A(9),...

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PubMed Original Article Evidence Unclassified

Extraskeletal Ewing's sarcoma.

Cancer | 1999 | Ahmad R, Mayol BR, Davis M, Rougraff BT

[Indexed for MEDLINE] 15. Strahlenther Onkol. 1993 Dec;169(12):695-708. [Therapy of Ewing's sarcoma]. [Article in German] Dunst J(1), Sauer R. Author information: (1)Strahlentherapeutische Klinik und Poliklinik, Universität Erlangen-Nürnberg. Therapy of Ewing's sarcoma requires a qualified clinical, radiological, and pathohistological diagnosis and, in particular, an optimal th...

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PubMed Original Article Evidence Unclassified

Ewing's sarcoma.

Journal of surgical oncology | 1993 | Iyer RS, Rao SR, Gurjal A, Nair CN

[Indexed for MEDLINE] 12. Neurosurg Clin N Am. 2008 Jan;19(1):71-80. doi: 10.1016/j.nec.2007.10.001. Sarcoma and the spinal column. Wang VY(1), Potts M, Chou D. Author information: (1)Department of Neurological Surgery, University of California, 505 Parnassus Avenue, Room M779, San Francisco, CA 94143-0112, USA. Primary sarcomas are rare in the spine. Common primary sarcomas in...

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PubMed Original Article Evidence Unclassified

[Bone tumors].

La Pediatria medica e chirurgica : Medical and surgical pediatrics | 1984 | Madon E, Grazia G, Brach Del Prever A

[Indexed for MEDLINE] 17. J Bone Oncol. 2019 Jan 29;15:100221. doi: 10.1016/j.jbo.2019.100221. eCollection 2019 Apr. Advances in immune checkpoint inhibitors for bone sarcoma therapy. Thanindratarn P(1)(2), Dean DC(1), Nelson SD(3), Hornicek FJ(1), Duan Z(1). Author information: (1)Department of Orthopedic Surgery, Sarcoma Biology Laboratory, David Geffen School of Medicine, Un...

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