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PubMed Narrative Review Evidence Moderate

Advances in immune checkpoint inhibitors for bone sarcoma therapy.

Journal of bone oncology | 2019 | Thanindratarn P, Dean DC, Nelson SD, Hornicek FJ

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Source
PubMed
Type
Narrative Review
Evidence
Moderate

Abstract

18. Ochsner J. 2024 Fall;24(3):213-218. doi: 10.31486/toj.24.0014. Recurrent Intracranial Ewing Sarcoma. Yap SA(1)(2)(3), Alig AHS(1), Hasenburg AA(1), Hilfenhaus G(1), Stephan LU(1), Pelzer U(1), Stintzing S(1)(3), Stahler A(1). Author information: (1)Department of Hematology, Oncology and Cancer Immunology, Charité Universitätsmedizin, Berlin, Germany. (2)Department of Hematology, Oncology and Cancer Immunology, Charité Comprehensive Cancer Center, Charité Universitätsmedizin, Berlin, Germany. (3)German Cancer Consortium, German Cancer Research Center (DKFZ), Heidelberg, Germany. Background: Ewing sarcoma is a rare malignant neoplasm that is primarily localized in bone tissues. The prognosis for patients with a newly diagnosed localized Ewing sarcoma has been greatly improved by multimodality treatment. However, treating patients with disseminated or recurrent disease is challenging, with a 5-year overall survival rate of

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