Orthonotes
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Bone & Joint Infections in HIV

HIV patients prone to bacterial (Staph aureus), mycobacterial (TB), fungal infections. Salmonella is a classic cause of osteomyelitis in HIV, especially with sickle cell disease. Clinical: insidious bone/joint pain, fever, constitutional symptoms; consider atypical presentations. Investigations: cultures, biopsy, imaging (MRI sensitive for marrow involvement). Treatment: prolonged targeted antibiotics, ATT/antifungals as needed, surgical debridement, optimize HAART.