Orthonotes
Orthonotes
by the.bonestories
v3.0 Fusion
v3.0 Fusion
general topic hub

Bone & Joint Infections in HIV

HIV patients prone to bacterial (Staph aureus), mycobacterial (TB), fungal infections. Salmonella is a classic cause of osteomyelitis in HIV, especially with sickle cell disease. Clinical: insidious bone/joint pain, fever, constitutional symptoms; consider atypical presentations. Investigations: cultures, biopsy, imaging (MRI sensitive for marrow involvement). Treatment: prolonged targeted antibiotics, ATT/antifungals as needed, surgical debridement, optimize HAART.

Overview

Topic summary

View wiki
HIV patients prone to bacterial (Staph aureus), mycobacterial (TB), fungal infections. Salmonella is a classic cause of osteomyelitis in HIV, especially with sickle cell disease. Clinical: insidious bone/joint pain, fever, constitutional symptoms; consider atypical presentations. Investigations: cultures, biopsy, imaging (MRI sensitive for marrow involvement). Treatment: prolonged targeted antibiotics, ATT/antifungals as needed, surgical debridement, optimize HAART.
Cases

Clinical case discussions

Browse all cases
MCQs

High-yield practice questions

Start topic quiz
Question 1

Which organism is the most common cause of septic arthritis in HIV-infected patients?

Question 2

In HIV patients, at what CD4 count does the risk for opportunistic infections significantly increase?

Question 3

What is the typical presentation of septic arthritis in HIV patients compared to immunocompetent individuals?

Question 4

Which imaging modality is most sensitive for detecting marrow involvement in osteomyelitis in HIV patients?

Question 5

What is the standard initial management for septic arthritis in an HIV patient?

Question 6

Which of the following organisms is a classic cause of osteomyelitis in patients with HIV and sickle cell disease?

Question 7

In HIV patients, what laboratory finding is indicative of septic arthritis?

Question 8

What is the recommended empirical antibiotic coverage for septic arthritis in an HIV patient?

Question 9

Which type of mycobacteria is particularly associated with CD4 counts < 50/mm³ in HIV patients?

Question 10

What is a common musculoskeletal complication of long-term HIV and ART use?