Haemophilic Arthropathy
Caused by recurrent hemarthrosis in hemophilia A/B leading to synovitis, cartilage loss, and arthritis. Target joints: knee, ankle, elbow—recurrent bleeds produce synovial hypertrophy. Radiographic findings: squaring of patella, widened intercondylar notch, subchondral cysts. MRI: sensitive for synovial hypertrophy, hemosiderin deposition, and cartilage thinning. Treatment: prophylactic factor replacement, radiosynovectomy/arthroscopic synovectomy, arthroplasty in end‑stage.
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1Practised by MCQ
10What is the primary pathological process in haemophilic arthropathy?
mcqWhich of the following joints is most commonly affected in haemophilic arthropathy?
mcqIn the Arnold-Hilgartner classification, what characteristic is observed in Grade IV haemophilic arthropathy?
mcqWhich treatment is considered the standard of care for preventing arthropathy in patients with severe hemophil...
mcqWhat radiographic finding is characteristic of early-stage haemophilic arthropathy?
mcqWhich of the following treatments is indicated for patients with significant synovial hypertrophy in haemophil...
mcqWhat is the role of MRI in evaluating haemophilic arthropathy?
mcqWhat is the major complication associated with on-demand factor replacement therapy in patients with haemophil...
mcqWhat is the typical incidence of haemophilia A in male births?
mcqWhich of the following is a common clinical feature of advanced haemophilic arthropathy?