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Evidence Search

Search reputable indexed orthopaedic literature from multiple scholarly sources, classify the evidence, and link papers directly to wiki topics and cases.

Sources: PubMed, Europe PMC, Crossref

Linking results to Wiki: Osteomalacia and Rickets
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Results are classified automatically from source metadata across PubMed, Europe PMC, and Crossref.
PubMed Crossref
PubMed Narrative Review Evidence Moderate

The pathophysiology of hypophosphatemia.

Best practice & research. Clinical endocrinology & metabolism | 2024 | Ito N, Hidaka N, Kato H

[Indexed for MEDLINE] Conflict of interest statement: Declaration of Competing Interest N.I. receives research support from Kyowa Kirin co. ltd. The other authors (N.H., H.K.) have nothing to disclose. 2. Int J Mol Sci. 2022 Nov 28;23(23):14896. doi: 10.3390/ijms232314896. Osteomalacia Is Not a Single Disease. Cianferotti L(1). Author information: (1)Bone Metabolic Diseases Uni...

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PubMed Narrative Review Evidence Moderate

Vitamin D and bone health: What vitamin D can and cannot do.

Advances in food and nutrition research | 2024 | Holick MF

[Indexed for MEDLINE] 12. Pediatr Nephrol. 2020 Oct;35(10):1843-1854. doi: 10.1007/s00467-019-04290-y. Epub 2019 Aug 8. Mineralized tissues in hypophosphatemic rickets. Robinson ME(1), AlQuorain H(1), Murshed M(1), Rauch F(2). Author information: (1)Shriners Hospital for Children and McGill University, 1003 Boulevard Decarie, Montreal, Québec, H4A 0A9, Canada. (2)Shriners Hospi...

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PubMed Narrative Review Evidence Moderate

Phosphatonins: From Discovery to Therapeutics.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists | 2023 | Kritmetapak K, Kumar R

[Indexed for MEDLINE] 17. Clin Calcium. 2007 Oct;17(10):1536-42. [Drug-induced osteomalacia]. [Article in Japanese] Sato K(1). Author information: (1)Tokyo Women's Medical University, Institute of Clinical Endocrinology. In our country, calcium- or phosphate-deficient rickets/osteomalacia due to malnutrition are scarcely reported. However, osteomalacia induced by drugs, such as...

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PubMed Narrative Review Evidence Moderate

Osteomalacia Is Not a Single Disease.

International journal of molecular sciences | 2022 | Cianferotti L

[Indexed for MEDLINE] Conflict of interest statement: The author declares no conflict of interest with respect to this paper. 3. Endocr Rev. 2019 Aug 1;40(4):1109-1151. doi: 10.1210/er.2018-00126. Skeletal and Extraskeletal Actions of Vitamin D: Current Evidence and Outstanding Questions. Bouillon R(1), Marcocci C(2), Carmeliet G(1), Bikle D(3), White JH(4), Dawson-Hughes B(5),...

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PubMed Narrative Review Evidence Moderate

FGF23-related hypophosphatemic rickets/osteomalacia: diagnosis and new treatment.

Journal of molecular endocrinology | 2021 | Fukumoto S

[Indexed for MEDLINE] 16. Endocr Pract. 2023 Jan;29(1):69-79. doi: 10.1016/j.eprac.2022.09.007. Epub 2022 Oct 7. Phosphatonins: From Discovery to Therapeutics. Kritmetapak K(1), Kumar R(2). Author information: (1)Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand. (2)Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota. Electronic address: rkum...

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PubMed Narrative Review Evidence Moderate

Nutritional rickets & osteomalacia: A practical approach to management.

The Indian journal of medical research | 2020 | Uday S, Högler W

[Indexed for MEDLINE] Conflict of interest statement: None 6. Pediatr Nephrol. 2022 Oct;37(10):2289-2302. doi: 10.1007/s00467-022-05505-5. Epub 2022 Mar 29. Rickets guidance: part II-management. Haffner D(1)(2), Leifheit-Nestler M(3)(4), Grund A(3)(4), Schnabel D(5). Author information: (1)Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Ca...

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PubMed Narrative Review Evidence Moderate

Mineralized tissues in hypophosphatemic rickets.

Pediatric nephrology (Berlin, Germany) | 2020 | Robinson ME, AlQuorain H, Murshed M, Rauch F

[Indexed for MEDLINE] 13. Drugs. 2018 Apr;78(6):707-714. doi: 10.1007/s40265-018-0905-7. Burosumab: First Global Approval. Lamb YN(1). Author information: (1)Springer, Private Bag 65901, Mairangi Bay, Auckland, 0754, New Zealand. dru@adis.com. Burosumab (Crysvita®; Kyowa Hakko Kirin Co., Ltd. and Ultragenyx Pharmaceutical Inc.) is a fully human monoclonal antibody directed at f...

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PubMed Narrative Review Evidence Moderate

Skeletal and Extraskeletal Actions of Vitamin D: Current Evidence and Outstanding Questions.

Endocrine reviews | 2019 | Bouillon R, Marcocci C, Carmeliet G, Bikle D

[Indexed for MEDLINE] 4. Best Pract Res Clin Endocrinol Metab. 2011 Aug;25(4):585-91. doi: 10.1016/j.beem.2011.05.002. The effect of vitamin D on bone and osteoporosis. Lips P(1), van Schoor NM. Author information: (1)Endocrine Section, Department of Internal Medicine, VU University Medical Center, Amsterdam, The Netherlands. p.lips@vumc.nl The main effect of the active vitamin...

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PubMed Narrative Review Evidence Moderate

Burosumab: First Global Approval.

Drugs | 2018 | Lamb YN

[Indexed for MEDLINE] 14. Curr Osteoporos Rep. 2012 Jun;10(2):151-9. doi: 10.1007/s11914-012-0098-z. Vitamin D and bone. Bikle DD(1). Author information: (1)University of California, San Francisco, San Francisco, CA, USA. Daniel.bikle@ucsf.edu All cells comprising the skeleton-chondrocytes, osteoblasts, and osteoclasts-contain both the vitamin D receptor and the enzyme CYP27B1...

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PubMed Narrative Review Evidence Moderate

Vitamin D and bone.

Current osteoporosis reports | 2012 | Bikle DD

[Indexed for MEDLINE] Conflict of interest statement: Disclosure Conflicts of interest: D.D. Bikle: has received grant support from the National Institutes of Health (RO1 DK054793, AR055924, and AR050023); and receives loyalties from Lange textbook chapter. 15. J Mol Endocrinol. 2021 Feb;66(2):R57-R65. doi: 10.1530/JME-20-0089. FGF23-related hypophosphatemic rickets/osteomalaci...

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PubMed Narrative Review Evidence Moderate

The effect of vitamin D on bone and osteoporosis.

Best practice & research. Clinical endocrinology & metabolism | 2011 | Lips P, van Schoor NM

[Indexed for MEDLINE] 5. Indian J Med Res. 2020 Oct;152(4):356-367. doi: 10.4103/ijmr.IJMR_1961_19. Nutritional rickets & osteomalacia: A practical approach to management. Uday S(1), Högler W(2). Author information: (1)Department of Endocrinology & Diabetes, Birmingham Women's & Children's NHS Foundation Trust; Institute of Metabolism & Systems Research, University of Birmingha...

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PubMed Original Article Evidence Unclassified

[Osteomalacia].

Vnitrni lekarstvi | 2023 | Rosa J

[Indexed for MEDLINE] 10. JCI Insight. 2023 Dec 22;8(24):e156850. doi: 10.1172/jci.insight.156850. FGF23 directly inhibits osteoprogenitor differentiation in Dmp1-knockout mice. Courbon G(1), Kentrup D(1), Thomas JJ(1), Wang X(1), Tsai HH(1), Spindler J(1), Von Drasek J(1), Ndjonko LM(1), Martinez-Calle M(1), Lynch S(1), Hivert L(1), Wang X(2), Chang W(3), Feng JQ(4), David V(1...

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PubMed Original Article Evidence Unclassified

FGF23 directly inhibits osteoprogenitor differentiation in Dmp1-knockout mice.

JCI insight | 2023 | Courbon G, Kentrup D, Thomas JJ, Wang X

[Indexed for MEDLINE] 11. Adv Food Nutr Res. 2024;109:43-66. doi: 10.1016/bs.afnr.2024.04.002. Epub 2024 May 16. Vitamin D and bone health: What vitamin D can and cannot do. Holick MF(1). Author information: (1)Section of Endocrinology, Diabetes, Nutrition and Weight Management, Department of Medicine, Boston University School of Medicine, Boston, MA, United States. Electronic...

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PubMed Original Article Evidence Unclassified

Rickets guidance: part II-management.

Pediatric nephrology (Berlin, Germany) | 2022 | Haffner D, Leifheit-Nestler M, Grund A, Schnabel D

[Indexed for MEDLINE] Conflict of interest statement: D.H. and D.S. received speaker fees, consultation fees, and research grants from Kyowa Kirin. All other authors declare no conflict of interest. 7. Baillieres Clin Endocrinol Metab. 1997 Apr;11(1):145-63. doi: 10.1016/s0950-351x(97)80569-1. Osteomalacia. Francis RM(1), Selby PL. Author information: (1)University of Newcastle...

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PubMed Narrative Review Evidence Moderate

[Drug-induced osteomalacia].

Clinical calcium | 2007 | Sato K

[Indexed for MEDLINE] 18. Am J Surg Pathol. 1989 Jul;13(7):588-99. doi: 10.1097/00000478-198907000-00007. Tumor-induced osteomalacia and rickets. Nuovo MA(1), Dorfman HD, Sun CC, Chalew SA. Author information: (1)Department of Pathology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York 100467-2490. Tumor-induced osteomalacia is a clinicopathologic...

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PubMed Narrative Review Evidence Moderate

[Nutrition-related bone disease].

Nihon rinsho. Japanese journal of clinical medicine | 2006 | Hirota K, Hirota T

[Indexed for MEDLINE] 20. Ann Endocrinol (Paris). 2022 Feb;83(1):46-53. doi: 10.1016/j.ando.2021.12.001. Epub 2021 Dec 16. Endocrinology of bone mineralization: An update. Jannin A(1), Kerlan V(2), Desailloud R(3). Author information: (1)Department of Endocrinology, Diabetology, Metabolism and Nutrition, University Hospital of Lille, Lille, France; University of Lille, Lille, F...

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PubMed Narrative Review Evidence Moderate

Osteomalacia.

Bailliere's clinical endocrinology and metabolism | 1997 | Francis RM, Selby PL

[Indexed for MEDLINE] 8. Annu Rev Nutr. 1984;4:471-91. doi: 10.1146/annurev.nu.04.070184.002351. Calcium and osteoporosis. Avioli LV. It has become increasingly apparent that the pathogenesis of osteoporosis is complex, poorly understood, and ill-defined. Calcium deficiency and/or calcium malabsorption and the homeostatic response to this biological insult may ultimately prove...

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PubMed Narrative Review Evidence Moderate

Calcium and osteoporosis.

Annual review of nutrition | 1984 | Avioli LV

[Indexed for MEDLINE] 9. Vnitr Lek. 2023 Summer;69(4):254-260. doi: 10.36290/vnl.2023.048. [Osteomalacia]. [Article in Czech] Rosa J. Osteomalacia with characteristic histomorphometric, radiographic, laboratory and clinical features is a prominent syndrome of disturbed bone mineralisation in adulthood. From an etiological point of view, osteomalacia is usually caused by substra...

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PubMed Case Report / Series Evidence Low

Tumor-induced osteomalacia and rickets.

The American journal of surgical pathology | 1989 | Nuovo MA, Dorfman HD, Sun CC, Chalew SA

[Indexed for MEDLINE] 19. Nihon Rinsho. 2006 Sep;64(9):1707-11. [Nutrition-related bone disease]. [Article in Japanese] Hirota K(1), Hirota T. Author information: (1)Obstetrics and Gynecology, Nissei Hospital and Research Laboratory. Bone disorders clearly related to nutrition are osteomalacia and osteoporosis. Osteomalacia is caused by a deficiency of vitamin D or a disturbanc...

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