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Evidence Search

Search reputable indexed orthopaedic literature from multiple scholarly sources, classify the evidence, and link papers directly to wiki topics and cases.

Sources: PubMed, Europe PMC, Crossref

Linking results to Wiki: Periprosthetic Joint Infection — Principles
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Results are classified automatically from source metadata across PubMed, Europe PMC, and Crossref.
PubMed Crossref
PubMed Randomized Controlled Trial Evidence High

Reverse shoulder arthroplasty or nothing for patients with displaced proximal humeral fractures: a randomized controlled trial.

Journal of shoulder and elbow surgery | 2024 | Miquel J, Cassart E, Santana F, Martínez R

[Indexed for MEDLINE] 13. Antibiotics (Basel). 2024 Aug 15;13(8):772. doi: 10.3390/antibiotics13080772. Antimicrobial Regimens in Cement Spacers for Periprosthetic Joint Infections: A Critical Review. Naoum S(1), Koutserimpas C(2)(3), Pantekidis I(4), Giovanoulis V(5), Veizi E(6), Piagkou M(3), Ioannou P(7), Samonis G(7)(8), Domouchtsidou A(9), Tsantes AG(9)(10), Papadopoulos D...

PubMed Narrative Review Evidence Moderate

Optimizing Antibiotic Therapy in Musculoskeletal Infections.

Infectious disease clinics of North America | 2025 | Cortés-Penfield NW, Justo JA, McCreary EK, Ryder JH

[Indexed for MEDLINE] 3. J Bone Joint Surg Am. 2024 Dec 4;106(23):2265-2275. doi: 10.2106/JBJS.23.01073. Epub 2024 Oct 30. Shoulder Periprosthetic Joint Infection: Principles of Prevention, Diagnosis, and Treatment. Nazzal EM(1), Herman ZJ(1), Como M(1), Kaarre J(1), Reddy RP(1), Wagner ER(2), Klatt BA(1), Lin A(1). Author information: (1)Department of Orthopaedic Surgery, Univ...

PubMed Narrative Review Evidence Moderate

Shoulder Periprosthetic Joint Infection: Principles of Prevention, Diagnosis, and Treatment.

The Journal of bone and joint surgery. American volume | 2024 | Nazzal EM, Herman ZJ, Como M, Kaarre J

[Indexed for MEDLINE] Conflict of interest statement: Disclosure: The Disclosure of Potential Conflicts of Interest forms are provided with the online version of the article ( http://links.lww.com/JBJS/I242 ). 4. Infect Dis Clin North Am. 2017 Jun;31(2):237-252. doi: 10.1016/j.idc.2017.01.009. Epub 2017 Mar 30. Management of Prosthetic Joint Infection. Tande AJ(1), Gomez-Urena...

PubMed Narrative Review Evidence Moderate

Proceedings of the United Kingdom Periprosthetic Joint Infection Meeting 2022: Combined and Arthroplasty Sessions.

The Journal of arthroplasty | 2024 | Razii N, Kennedy IW, Shields DW, Hrycaiczuk A

[Indexed for MEDLINE] 11. JBJS Essent Surg Tech. 2024 Feb 23;14(1):e22.00064. doi: 10.2106/JBJS.ST.22.00064. eCollection 2024 Jan-Mar. Constructing an Osseointegrated Prosthetic Leg. Kafedzic H(1), Rozbruch SR(2), Reif TJ(2), Hoellwarth JS(2). Author information: (1)Eschen Prosthetics and Orthotics, New York, NY. (2)Osseointegration Limb Replacement Center, Hospital for Special...

PubMed Narrative Review Evidence Moderate

Antimicrobial Regimens in Cement Spacers for Periprosthetic Joint Infections: A Critical Review.

Antibiotics (Basel, Switzerland) | 2024 | Naoum S, Koutserimpas C, Pantekidis I, Giovanoulis V

Conflict of interest statement: The authors declare no conflicts of interest. 14. Arthroplasty. 2023 Mar 2;5(1):10. doi: 10.1186/s42836-023-00169-4. Antimicrobial treatment of patients with a periprosthetic joint infection: basic principles. Rottier W(1), Seidelman J(2), Wouthuyzen-Bakker M(3). Author information: (1)Department of Medical Microbiology and Infection Prevention,...

PubMed Narrative Review Evidence Moderate

Principles of mechanical and chemical debridement with implant retention.

Arthroplasty (London, England) | 2023 | Deckey DG, Christopher ZK, Bingham JS, Spangehl MJ

Conflict of interest statement: The authors declare that they have no competing interests. 8. Antibiotics (Basel). 2025 Jun 6;14(6):585. doi: 10.3390/antibiotics14060585. Periprosthetic Joint Infection in Unicompartmental vs. Total Knee Arthroplasty: Microbiological Spectrum and Management Outcomes. Nazlıgül AS(1), Güven Ş(2), Erdoğan Y(3), Fırat A(4), Doğan M(2), Akkaya M(5)(6...

PubMed Narrative Review Evidence Moderate

Management of soft tissues in patients with periprosthetic joint infection.

Arthroplasty (London, England) | 2023 | Shao H, Zhou Y

Conflict of interest statement: None. 10. J Arthroplasty. 2024 Jan;39(1):218-223. doi: 10.1016/j.arth.2023.06.039. Epub 2023 Jun 30. Proceedings of the United Kingdom Periprosthetic Joint Infection Meeting 2022: Combined and Arthroplasty Sessions. Razii N(1), Kennedy IW(1), Shields DW(1), Hrycaiczuk A(1), Morgan-Jones R(2), Meek RMD(1), Jamal B(1). Author information: (1)Depart...

PubMed Narrative Review Evidence Moderate

Antimicrobial treatment of patients with a periprosthetic joint infection: basic principles.

Arthroplasty (London, England) | 2023 | Rottier W, Seidelman J, Wouthuyzen-Bakker M

Conflict of interest statement: The authors report no conflict of interest. 15. Z Orthop Unfall. 2021 Oct;159(5):565-582. doi: 10.1055/a-1149-9654. Epub 2020 Sep 30. [Revision Total Knee Arthroplasty]. [Article in German] Kremer M, Gramlich Y, Hoffmann R. In addition to periprosthetic infections (PJI), the reconstruction of bony defects is the major challenge of revision total...

PubMed Narrative Review Evidence Moderate

[Fracture-related infections after intramedullary nailing : Diagnostics and treatment].

Der Unfallchirurg | 2022 | Rupp M, Bärtl S, Lang S, Walter N

[Indexed for MEDLINE] 20. World J Orthop. 2020 Dec 18;11(12):559-572. doi: 10.5312/wjo.v11.i12.559. eCollection 2020 Dec 18. Systematic review of single stage revision for prosthetic joint infection. Lum ZC(1), Holland CT(2), Meehan JP(3). Author information: (1)Department of Orthopaedic Surgery, Davis Medical Center, University of California, Sacramento, CA 95817, United State...

PubMed Narrative Review Evidence Moderate

Fracture-related infection: current methods for prevention and treatment.

Expert review of anti-infective therapy | 2020 | Foster AL, Moriarty TF, Trampuz A, Jaiprakash A

[Indexed for MEDLINE] 6. Bull Hosp Jt Dis (2013). 2018 Mar;76(1):55-61. Strategies for Management of Periprosthetic Joint Infection. Riesgo AM, Liporace FA. Periprosthetic joint infection (PJI) is one of the most catastrophic and difficult to manage complications following total hip and total knee arthroplasty. As the number of total joint arthroplasties continues to increase,...

PubMed Narrative Review Evidence Moderate

Specificities of total hip and knee arthroplasty revision for infection.

Orthopaedics & traumatology, surgery & research : OTSR | 2020 | Jenny JY

[Indexed for MEDLINE] 19. Unfallchirurg. 2022 Jan;125(1):50-58. doi: 10.1007/s00113-021-01117-0. Epub 2021 Dec 18. [Fracture-related infections after intramedullary nailing : Diagnostics and treatment]. [Article in German; Abstract available in German from the publisher] Rupp M(1), Bärtl S(1), Lang S(1), Walter N(1), Alt V(2). Author information: (1)Klinik und Poliklinik für Un...

PubMed Narrative Review Evidence Moderate

Strategies for Management of Periprosthetic Joint Infection.

Bulletin of the Hospital for Joint Disease (2013) | 2018 | Riesgo AM, Liporace FA

[Indexed for MEDLINE] 7. Arthroplasty. 2023 Apr 6;5(1):16. doi: 10.1186/s42836-023-00170-x. Principles of mechanical and chemical debridement with implant retention. Deckey DG(1), Christopher ZK(1), Bingham JS(1), Spangehl MJ(2). Author information: (1)Department of Orthopaedic Surgery, Mayo Clinic, Phoenix, AZ, 85054, USA. (2)Department of Orthopaedic Surgery, Mayo Clinic, Pho...

PubMed Narrative Review Evidence Moderate

Management of Prosthetic Joint Infection.

Infectious disease clinics of North America | 2017 | Tande AJ, Gomez-Urena EO, Berbari EF, Osmon DR

[Indexed for MEDLINE] 5. Expert Rev Anti Infect Ther. 2020 Apr;18(4):307-321. doi: 10.1080/14787210.2020.1729740. Epub 2020 Feb 19. Fracture-related infection: current methods for prevention and treatment. Foster AL(1)(2)(3)(4), Moriarty TF(1), Trampuz A(5), Jaiprakash A(2), Burch MA(1), Crawford R(2), Paterson DL(6), Metsemakers WJ(7)(8), Schuetz M(2)(3)(4), Richards RG(1). Au...

PubMed Narrative Review Evidence Moderate

Preoperative and intraoperative infection workup in apparently aseptic revision shoulder arthroplasty.

Journal of shoulder and elbow surgery | 2015 | Updegrove GF, Armstrong AD, Kim HM

[Indexed for MEDLINE] 18. Orthop Traumatol Surg Res. 2020 Feb;106(1S):S27-S34. doi: 10.1016/j.otsr.2019.05.020. Epub 2019 Dec 5. Specificities of total hip and knee arthroplasty revision for infection. Jenny JY(1). Author information: (1)Pôle Locomax, hôpitaux universitaires de Strasbourg, 1, avenue Molière, 67200 Strasbourg, France. Electronic address: jean-yves.jenny@chru-str...

PubMed Narrative Review Evidence Moderate

Identification and preoperative optimization of risk factors to prevent periprosthetic joint infection.

World journal of orthopedics | 2014 | Baek SH

17. J Shoulder Elbow Surg. 2015 Mar;24(3):491-500. doi: 10.1016/j.jse.2014.10.005. Epub 2014 Dec 2. Preoperative and intraoperative infection workup in apparently aseptic revision shoulder arthroplasty. Updegrove GF(1), Armstrong AD(1), Kim HM(2). Author information: (1)Department of Orthopaedics and Rehabilitation, Penn State College of Medicine, Milton S. Hershey Medical Cent...

PubMed Original Article Evidence Unclassified

Periprosthetic Joint Infection in Unicompartmental vs. Total Knee Arthroplasty: Microbiological Spectrum and Management Outcomes.

Antibiotics (Basel, Switzerland) | 2025 | Nazlıgül AS, Güven Ş, Erdoğan Y, Fırat A

Conflict of interest statement: The authors declare no conflicts of interest. 9. Arthroplasty. 2023 Oct 3;5(1):52. doi: 10.1186/s42836-023-00205-3. Management of soft tissues in patients with periprosthetic joint infection. Shao H(1), Zhou Y(2). Author information: (1)Department of Orthopaedic Surgery, Beijing Jishuitan Hospital, Capital Medical University, Fourth Clinical Coll...

PubMed Original Article Evidence Unclassified

Constructing an Osseointegrated Prosthetic Leg.

JBJS essential surgical techniques | 2024 | Kafedzic H, Rozbruch SR, Reif TJ, Hoellwarth JS

Conflict of interest statement: Disclosure: The Disclosure of Potential Conflicts of Interest forms are provided with the online version of the article (http://links.lww.com/JBJSEST/A436). 12. J Shoulder Elbow Surg. 2024 Oct;33(10):2187-2195. doi: 10.1016/j.jse.2024.02.023. Epub 2024 Mar 26. Reverse shoulder arthroplasty or nothing for patients with displaced proximal humeral f...

Crossref Journal Article Evidence Unclassified

Case Reports: Periprosthetic Joint Infection after Total Joint Arthroplasty Following Swimming Activity

Journal of Orthopaedic Case Reports | 2024 | Aviram Albagly, Ariel D Levine, Oren Ben-Lulu

Introduction: Periprosthetic joint infection (PJI) is a severe complication of total joint arthroplasty (TJA), occurring in approximately 1–2% of primary procedures. These infections, characterized by an overall weighted mean incidence of 0.97% for total hip arthroplasty (THA) and 1.03% for total knee arthroplasty (TKA), pose significant challenges for patients and health-care...

PubMed Original Article Evidence Unclassified

[Revision Total Knee Arthroplasty].

Zeitschrift fur Orthopadie und Unfallchirurgie | 2021 | Kremer M, Gramlich Y, Hoffmann R

[Indexed for MEDLINE] Conflict of interest statement: Erklärung zu finanziellen Interessen Forschungsförderung erhalten: nein; Honorar/geldwerten Vorteil für Referententätigkeit erhalten: ja; Bezahlter Berater/interner Schulungsreferent/Gehaltsempfänger: ja; Patent/Geschäftsanteile/Aktien (Autor/Partner, Ehepartner, Kinder) an im Bereich der Medizin aktiven Firma: nein; Patent/...

Crossref Scholarly Work Evidence Unclassified

7 Management of Periprosthetic Joint Infection

Management of Orthopaedic Infections | 2021

Periprosthetic joint infection (PJI) continues to be a devastating problem in the field of total joint arthroplasty. There are a number of surgical options to decide from and management decisions are based upon the interplay between host, pathogen, and surgeon characteristics. The goal of management is to maximize function, prevent systemic complications, and eradicate infectio...

PubMed Original Article Evidence Unclassified

General treatment principles for fracture-related infection: recommendations from an international expert group.

Archives of orthopaedic and trauma surgery | 2020 | Metsemakers WJ, Morgenstern M, Senneville E, Borens O

[Indexed for MEDLINE] Conflict of interest statement: All authors declare no conflict of interest with respect to the preparation and writing of this article. 2. Infect Dis Clin North Am. 2025 Sep;39(3):361-382. doi: 10.1016/j.idc.2025.02.009. Epub 2025 Apr 11. Optimizing Antibiotic Therapy in Musculoskeletal Infections. Cortés-Penfield NW(1), Justo JA(2), McCreary EK(3), Ryder...

Crossref Journal Article Evidence Unclassified

Modulating antibiotic release from reservoirs in 3D‐printed orthopedic devices to treat periprosthetic joint infection

Journal of Orthopaedic Research | 2020 | Brian Allen, Christina Moore, Thorsten Seyler, Ken Gall

AbstractPeriprosthetic joint infection is a costly debilitating affliction following total joint arthroplasty. Despite a relatively low incidence rate, periprosthetic joint infection is an increasing problem due to a substantial increase in arthroplasty surgeries over time. The current treatment is replacing the primary implant with a temporary bone cement spacer that releases...

Crossref Journal Article Evidence Unclassified

Forced-air warming discontinued: periprosthetic joint infection rates drop

Orthopedic Reviews | 2017 | Scott D. Augustine

Several studies have shown that the waste heat from forced-air warming (FAW) escapes near the floor and warms the contaminated air resident near the floor. The waste heat then forms into convection currents that rise up and contaminate the sterile field above the surgical table. It has been shown that a single airborne bacterium can cause a periprosthetic joint infection (PJI)...