European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society | 2025 | Post AM, Gaume M, van Royen BJ, Janssen E
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[Indexed for MEDLINE] Conflict of interest statement: Declarations. Conflict of interest: Conflic of interest The device(s)/drug(s) is/are FDA-approved or approved by corresponding national agency for this indication. No funds were received in support of this work. Relevant financial activities outside the submitted work: A.M. Post: no conflict of interest/ relevant financial activities M. Gaume: no conflict of interest/ relevant financial activities B.J. van Royen: no conflict of interest/ relevant financial activities E.R.C. Janssen: no conflict of interest/ relevant financial activities K.M. Lundine: Institutional research support funding from Euros Spine and Globus Spine M.B. Johnson: Institutional research support funding from Euros Spine and Globus Spine P. Neagoe: no conflict of interest/ relevant financial activities M.C. Kruyt: Euros research grant of 25.000 euro in 2020 L. Boissiere: Consultant and research support from Clarian Spinevision and travel accommodation from Euros JP. Kaleeta Maalu: no conflict of interest/ relevant financial activities J.J.M. Renkens: no conflict of interest/ relevant financial activities M.C. Deml: no conflict of interest/ relevant financial activities A. Stadhouder; yearly institutional research support funding from Euros F. Solla: Funding for congresses and meetings from Medtronic and SMAIO S. Schaible: no conflict of interest/ relevant financial activities C.S. Tabeling: no conflict of interest/ relevant financial activities J. Mielenbrink: no conflict of interest/ relevant financial activities L. Miladi: intellectual property rights with Euros company. 17. J Bone Joint Surg Am. 1995 Sep;77(9):1362-9. doi: 10.2106/00004623-199509000-00012. Scoliosis in familial dysautonomia. Operative treatment. Rubery PT(1), Spielman JH, Hester P, Axelrod E, Burke SW, Levine DB. Author information: (1)Hospital for Special Surgery, New York Hospital-Cornell University Medical College, New York City, USA. The results of operative treatment of scoliosis were reviewed for twenty-two patients (ten boys and twelve girls) who had familial dysautonomia, an autosomal recessive disorder affecting primarily Ashkenazi Jews. The indication for operative intervention was progressive kyphoscoliosis to 45 degrees or more in a skeletally immature patient for whom bracing had failed. The mean age at the time of the operation was fifteen years and five months (range, eight years and two months to nineteen years). Seventeen patients had a thoracic curve with a mean preoperative Cobb angle of 69 degrees (range, 47 to 112 degrees), and five patients had a double major curve with a mean preoperative Cobb angle of 71 degrees (range, 42 to 87 degrees) for the cephalad curves and 60 degrees (range, 45 to 72 degrees) for the caudad curves. Twenty patients had a rigid kyphosis; in fourteen, the apex was at the seventh thoracic vertebra or more cephalad. Two patients had a lordoscoliosis. The mean preoperative kyphosis was 64 degrees (range, 12 to 110 degrees) in the thirteen patients who had a thoracic curve and for whom information regarding kyphosis was available, and it was 70 degrees (range, 54 to 84 degrees) in the five patients who had a double major curve. Postoperior spinal arthrodesis and instrumentation was performed in all patients. Two patients had an anterior arthrodesis as well because of the severity and rigidity of the curve. Allograft bone was used in eighteen patients. Postoperatively, all patients were managed with a body cast or with a custom-molded thoracolumbar brace.(ABSTRACT TRUNCATED AT 250 WORDS) DOI: 10.2106/00004623-199509000-00012
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