Journal of personalized medicine | 2023 | Benignus C, Buschner P, Meier MK, Wilken F
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Conflict of interest statement: The authors declare no conflict of interest. 16. Arch Orthop Trauma Surg. 2024 Nov;144(11):4827-4838. doi: 10.1007/s00402-024-05569-y. Epub 2024 Sep 19. Does patient-specific instrument or robot improve imaging and functional outcomes in unicompartmental knee arthroplasty? A bayesian analysis. Jiao X(1)(2), Du M(3), Li Q(2)(4), Huang C(1), Ding R(1), Wang W(5). Author information: (1)Department of Orthopaedic Surgery, China-Japan Friendship Hospital, Beijing, P.R. China. (2)Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, P.R. China. (3)Department of Orthopaedic Surgery, Xuanwu Hospital Capital Medical University, Beijing, P.R. China. (4)Medical Research and Biometrics Center, Fuwai Hospital, National Clinical Research Center for Cardiovascular Diseases, National Center for Cardiovascular Diseases, Beijing, P.R. China. (5)Department of Orthopaedic Surgery, China-Japan Friendship Hospital, Beijing, P.R. China. jointwwg@163.com. INTRODUCTION: This study conducted a Bayesian network meta-analysis (NMA) to compare the imaging and functional outcomes of patient-specific instrument-assisted unicompartmental knee arthroplasty (P-UKA), robot-assisted unicompartmental knee arthroplasty (R-UKA), and conventional unicompartmental knee arthroplasty (C-UKA). MATERIALS AND METHODS: A comprehensive search was performed on five electronic databases and major orthopedic journals as of September 24, 2023. We included randomized controlled studies featuring at least two interventions of P-UKA, R-UKA, or C-UKA. Primary outcomes encompassed the deviation angle of hip-knee-ankle angle, as well as the coronal and sagittal plane alignment of femoral and tibial components. Secondary outcomes included patient-reported outcome measures (PROM), surgery time, revision rate, and complication rate. Bayesian framework was employed for risk ratio (RR) or mean deviation (MD) analysis, and treatment hierarchy was established based on rank probabilities. RESULTS: This NMA included 871 knees from 12 selected studies. In sagittal plane, R-UKA exhibited a significantly reduced deviation angle of femoral component compared to P-UKA (MD: 4.16, 95% CI: 0.21, 8.07), and of tibial component in comparison to C-UKA (MD: -2.45, 95% CI: -4.20, -0.68). Notably, the surgery time was significantly longer in R-UKA than in C-UKA (MD: 15.98, 95% CI: 3.11, 28.88). However, no significant differences were observed in other outcomes. CONCLUSION: Compared with P-UKA or C-UKA, R-UKA significantly improves the femoral and tibial component alignment in the sagittal plane, although this does not translate into discernible differences in functional outcomes. Comprehensive considerations of economic and learning costs are imperative for the judicious selection of the appropriate procedure. © 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature. DOI: 10.1007/s00402-024-05569-y
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