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Evidence Search

Search reputable indexed orthopaedic literature from multiple scholarly sources, classify the evidence, and link papers directly to wiki topics and cases.

Sources: PubMed, Europe PMC, Crossref

Linking results to Wiki: Giant Cell Tumor — Campanacci Classification
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Results are classified automatically from source metadata across PubMed, Europe PMC, and Crossref.
PubMed Crossref
PubMed Systematic Review / Meta-analysis Evidence High

[Meta-analysis of risk factors of recurrence in patients with giant cell tumor on extremities].

Zhonghua yi xue za zhi | 2014 | Li R, Hu Y

[Indexed for MEDLINE] 10. Balkan Med J. 2016 Sep;33(5):496-503. doi: 10.5152/balkanmedj.2016.150473. Epub 2016 Sep 1. Advantages of Pressurized-Spray Cryosurgery in Giant Cell Tumors of the Bone. Dabak N(1), Göçer H(1), Çıraklı A(2). Author information: (1)Department of Orthopedic and Traumatology, Ondokuz Mayıs University School of Medicine, Samsun, Turkey. (2)Orthopedic and T...

PubMed Original Article Evidence Unclassified

A New Relevant Integrated Radiologic and Surgical Classification Scheme for Giant Cell Tumors of Bones.

Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews | 2025 | Chang YC, Pretell-Mazzini J, Temple HT, Soler R

[Indexed for MEDLINE] 9. Zhonghua Yi Xue Za Zhi. 2014 Dec 23;94(47):3778-83. [Meta-analysis of risk factors of recurrence in patients with giant cell tumor on extremities]. [Article in Chinese] Li R(1), Hu Y(2). Author information: (1)Department of Orthopedics, First Hospital, Jiamusi University, Heilongjiang 154002, China. (2)Department of Bone Tumor, Tianjin Hospital, Tianjin...

PubMed Original Article Evidence Unclassified

Soft tissue recurrence in giant cell tumor of bone: Risk factors and radiological and histopathological features.

Acta orthopaedica et traumatologica turcica | 2025 | Mirioğlu A, Dalkır KA, Ölke HC, Kundakçı B

[Indexed for MEDLINE] Conflict of interest statement: Declaration of Interests: Mehmet Ali Deveci is an Associate Editor at Acta Orthopaedica et Traumatologica Turcica, however; his involvement in the peer review process was solely as an author. The other authors have no conflict of interest to declare. 16. Rev Bras Ortop (Sao Paulo). 2022 Jul 7;57(5):802-806. doi: 10.1055/s-00...

PubMed Original Article Evidence Unclassified

Giant cell tumor of bone at distal radius suffered more soft tissue recurrence and ultrasonography is effective to detect the soft tissue recurrence.

Discover oncology | 2024 | Cui L, Sun Y, Jin T, Fan D

Conflict of interest statement: No benefits in any form have been or will be received from a commercial party related directly or indirectly to the subject of this manuscript. 6. Int J Surg Case Rep. 2019;61:202-206. doi: 10.1016/j.ijscr.2019.07.052. Epub 2019 Jul 26. En bloc giant cell tumor resection following direct hemiarthroplasty shoulder reconstruction-functional outcome...

PubMed Case Report / Series Evidence Low

En bloc giant cell tumor resection following direct hemiarthroplasty shoulder reconstruction-functional outcome: A case report.

International journal of surgery case reports | 2019 | Usman MA, Prasatia Sam AD, Wijaya M, Firdaus RM

Conflict of interest statement: No conflict of interest. 7. J Cancer Res Clin Oncol. 2023 Jul;149(8):4653-4661. doi: 10.1007/s00432-022-04348-9. Epub 2022 Oct 3. Microwave in situ inactivation in the treatment of bone giant cell tumor: a mid-term descriptive study. Jiang X(#)(1), Chen J(#)(1)(2), Zhou W(1), Zhang C(1), Wang G(1), Dong D(1), Xia P(3), Liu X(1), Xu F(1). Author i...

PubMed Original Article Evidence Unclassified

Twofold Expression of Receptor Tyrosine Kinase 2 (ROR2) in Giant Cell Tumors of Bone: Outcome of a Case‒Control Study.

Indian journal of surgical oncology | 2024 | S S, Nema SK, Tripathi SK, P KS

Conflict of interest statement: Conflict of InterestThe authors declare no competing interests. 12. BMC Musculoskelet Disord. 2022 Dec 5;23(1):1061. doi: 10.1186/s12891-022-06005-1. Mid-term results of giant cell tumours with pathologic fractures around the knee: a multicentre retrospective study. Zhao L(1), Chen J(2), Hu Y(3), Ye Z(4), Tao K(5). Author information: (1)Departme...

PubMed Original Article Evidence Unclassified

Microwave in situ inactivation in the treatment of bone giant cell tumor: a mid-term descriptive study.

Journal of cancer research and clinical oncology | 2023 | Jiang X, Chen J, Zhou W, Zhang C

[Indexed for MEDLINE] Conflict of interest statement: The authors declare that they have no competing interests. 8. J Am Acad Orthop Surg Glob Res Rev. 2025 Jul 17;9(7):e24.00321. doi: 10.5435/JAAOSGlobal-D-24-00321. eCollection 2025 Jul 1. A New Relevant Integrated Radiologic and Surgical Classification Scheme for Giant Cell Tumors of Bones. Chang YC(1), Pretell-Mazzini J, Tem...

PubMed Original Article Evidence Unclassified

Complications of surgery for giant cell tumor of bone in the extremities: Incidence, risk factors, management modality, and impact on functional and oncological outcomes.

Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association | 2022 | Morii T, Asano N, Nakayama R, Kikuta K

[Indexed for MEDLINE] Conflict of interest statement: Declaration of competing interest The authors declare that they have no conflicts of interest. 5. Discov Oncol. 2024 Apr 4;15(1):103. doi: 10.1007/s12672-024-00918-0. Giant cell tumor of bone at distal radius suffered more soft tissue recurrence and ultrasonography is effective to detect the soft tissue recurrence. Cui L(1)(...

PubMed Original Article Evidence Unclassified

Mid-term results of giant cell tumours with pathologic fractures around the knee: a multicentre retrospective study.

BMC musculoskeletal disorders | 2022 | Zhao L, Chen J, Hu Y, Ye Z

[Indexed for MEDLINE] Conflict of interest statement: The authors declare that they have no conflict of interest. 13. Arch Orthop Trauma Surg. 2001;121(1-2):83-6. doi: 10.1007/s004020000158. Treatment of stages 2 and 3 giant-cell tumor. Labs K(1), Perka C, Schmidt RG. Author information: (1)Department of Orthopaedics, Charité Hospital, Humboldt University, Berlin, Germany. kars...

PubMed Original Article Evidence Unclassified

Treatment of Patients Diagnosed with Giant Cell Tumor of Bone: Experience of a Philanthropic Hospital in the State of Piauí, Brazil.

Revista brasileira de ortopedia | 2022 | Aguiar LTA, Vasconcelos JBM, Ribeiro MB

Conflict of interest statement: Conflito de Interesses Os autores declaram não haver conflito de interesses. 17. Acta Orthop Traumatol Turc. 2019 Sep;53(5):376-380. doi: 10.1016/j.aott.2019.05.005. Epub 2019 Jun 26. A new computerized tomography classification to evaluate response to Denosumab in giant cell tumors in the extremities. Campanacci L(1), Sambri A(2), Medellin MR(3)...

PubMed Original Article Evidence Unclassified

A new computerized tomography classification to evaluate response to Denosumab in giant cell tumors in the extremities.

Acta orthopaedica et traumatologica turcica | 2019 | Campanacci L, Sambri A, Medellin MR, Cimatti P

[Indexed for MEDLINE] 18. Int Orthop. 1993;17(2):87-92. doi: 10.1007/BF00183548. Giant cell tumour of bone. A surgical approach to grade III tumours. Rooney RJ(1), Asirvatham R, Lifeso RM, Ali MA, Parikh S. Author information: (1)Department of Orthopaedic Surgery, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia. Thirty-one patients with giant cell tumo...

PubMed Original Article Evidence Unclassified

Advantages of Pressurized-Spray Cryosurgery in Giant Cell Tumors of the Bone.

Balkan medical journal | 2016 | Dabak N, Göçer H, Çıraklı A

Conflict of interest statement: No conflict of interest was declared by the authors. 11. Indian J Surg Oncol. 2024 Dec;15(4):694-698. doi: 10.1007/s13193-024-01965-3. Epub 2024 May 28. Twofold Expression of Receptor Tyrosine Kinase 2 (ROR2) in Giant Cell Tumors of Bone: Outcome of a Case‒Control Study. S S(1), Nema SK(2), Tripathi SK(3), P KS(1). Author information: (1)Jawaharl...

PubMed Cohort / Comparative Study Evidence Moderate

Treatment of stages 2 and 3 giant-cell tumor.

Archives of orthopaedic and trauma surgery | 2001 | Labs K, Perka C, Schmidt RG

[Indexed for MEDLINE] 14. Rev Bras Ortop. 2016 Jan 5;51(1):58-62. doi: 10.1016/j.rboe.2015.12.012. eCollection 2016 Jan-Feb. Giant-cell tumor: analysis on the importance of early diagnosis and the epidemiological profile. de Carvalho Diniz Ferraz DF(1), Torres Dos Santos CA(1), Farias Costa VH(1), Gonçalves Souza AM(1), Gomes Lima PR(1). Author information: (1)Service of Orthop...

PubMed Original Article Evidence Unclassified

Giant-cell tumor: analysis on the importance of early diagnosis and the epidemiological profile.

Revista brasileira de ortopedia | 2016 | de Carvalho Diniz Ferraz DF, Torres Dos Santos CA, Farias Costa VH, Gonçalves Souza AM

15. Acta Orthop Traumatol Turc. 2025 Dec 31;59(6):470-476. doi: 10.5152/j.aott.2025.25440. Soft tissue recurrence in giant cell tumor of bone: Risk factors and radiological and histopathological features. Mirioğlu A(1), Dalkır KA(1), Ölke HC(2), Kundakçı B(1), Bağır M(1), Eren K(3), Deveci MA(4). Author information: (1)Department of Orthopaedics and Traumatology, Çukurova Unive...

PubMed Original Article Evidence Unclassified

The outcomes of treatment of giant cell tumor of bone around the knee.

Journal of the Medical Association of Thailand = Chotmaihet thangphaet | 2012 | Asavamongkolkul A, Eamsobhana P, Waikakul S, Phimolsarnti R

[Indexed for MEDLINE] 20. Orthop Surg. 2021 Feb;13(1):185-195. doi: 10.1111/os.12865. Epub 2021 Jan 13. Novel Strategy of Curettage and Adjuvant Microwave Therapy for the Treatment of Giant Cell Tumor of Bone in Extremities: A Preliminary Study. Ke J(#)(1)(2), Cheng S(#)(1), Yao MY(1), Chu X(1), Wang M(2), Zeng XL(1), Yang T(1), Zhang C(1), Zhong H(3), Zhang Y(1). Author inform...

PubMed Narrative Review Evidence Moderate

Recurrence of giant-cell tumors of the long bones after curettage and packing with cement.

The Journal of bone and joint surgery. American volume | 1994 | O'Donnell RJ, Springfield DS, Motwani HK, Ready JE

[Indexed for MEDLINE] 3. Zhonghua Yi Xue Za Zhi (Taipei). 1997 Apr;59(4):240-7. Giant-cell tumor of bone around the knee. Fong YC(1), Chen TH, Chen WM, Lo WH. Author information: (1)Department of Orthopedics, China Medical College Hospital, Taichung, Taiwan, R.O.C. BACKGROUND: In most of the reported series, almost half of the giant-cell tumors involved the knee region. The cha...

PubMed Narrative Review Evidence Moderate

Giant cell tumor of bone.

Clinical orthopaedics and related research | 1986 | Eckardt JJ, Grogan TJ

[Indexed for MEDLINE] 2. J Bone Joint Surg Am. 1994 Dec;76(12):1827-33. doi: 10.2106/00004623-199412000-00009. Recurrence of giant-cell tumors of the long bones after curettage and packing with cement. O'Donnell RJ(1), Springfield DS, Motwani HK, Ready JE, Gebhardt MC, Mankin HJ. Author information: (1)Orthopaedic Oncology Unit, Massachusetts General Hospital, Boston 02114. The...

PubMed Original Article Evidence Unclassified

Giant-cell tumor of bone around the knee.

Zhonghua yi xue za zhi = Chinese medical journal; Free China ed | 1997 | Fong YC, Chen TH, Chen WM, Lo WH

[Indexed for MEDLINE] 4. J Orthop Sci. 2022 May;27(3):681-688. doi: 10.1016/j.jos.2021.02.001. Epub 2021 Mar 5. Complications of surgery for giant cell tumor of bone in the extremities: Incidence, risk factors, management modality, and impact on functional and oncological outcomes. Morii T(1), Asano N(2), Nakayama R(2), Kikuta K(3), Susa M(4), Horiuchi K(4), Watanabe I(5), Anaz...

PubMed Original Article Evidence Unclassified

Giant cell tumour of bone. A surgical approach to grade III tumours.

International orthopaedics | 1993 | Rooney RJ, Asirvatham R, Lifeso RM, Ali MA

[Indexed for MEDLINE] 19. J Med Assoc Thai. 2012 Sep;95 Suppl 9:S122-8. The outcomes of treatment of giant cell tumor of bone around the knee. Asavamongkolkul A(1), Eamsobhana P, Waikakul S, Phimolsarnti R. Author information: (1)Department of Orthopaedic Surgery, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand. siaas@mahidol.ac.th BACKGROUND: Giant...

Crossref Scholarly Work Evidence Unclassified

Outcome of modular megaprosthesis in management of Campanacci Stage III Giant cell tumor around the knee - A Prospective Study

Journal unavailable | Ritwika Nandi, Pinaki Das, Sujit Narayan Nandi

Abstract Purpose : Juxta articular giant cell tumors around the knee constitute 50-60% of the total cases reported. If the disease is detected at an advanced stage, where it has already spread to extraosseous compartment or joint with pathological fractures, reconstruction of the joint after tumor excision poses problems and has poor functional outcome. In this article the func...