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Evidence Search

Search reputable indexed orthopaedic literature from multiple scholarly sources, classify the evidence, and link papers directly to wiki topics and cases.

Sources: PubMed, Europe PMC, Crossref

Linking results to Wiki: Osteomalacia and Rickets
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Results are classified automatically from source metadata across PubMed, Europe PMC, and Crossref.
PubMed Crossref
PubMed Narrative Review Evidence Moderate

Approach to a Child with Hypophosphatemia.

Biomolecules | 2025 | Antonowicz A, Lipiński P, Popow M, Skrzypczyk P

[Indexed for MEDLINE] Conflict of interest statement: The authors declare no conflicts of interest. 17. Eur J Radiol. 2003 May;46(2):85-95. doi: 10.1016/s0720-048x(03)00072-x. Imaging of renal osteodystrophy. Jevtic V(1). Author information: (1)Department of Radiology, Medical Faculty, University of Ljubljana, Zaloska 7, Slovenia. vladimir.jevtic@mf.uni-lj.si Chronic renal insu...

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PubMed Narrative Review Evidence Moderate

The pathophysiology of hypophosphatemia.

Best practice & research. Clinical endocrinology & metabolism | 2024 | Ito N, Hidaka N, Kato H

[Indexed for MEDLINE] Conflict of interest statement: Declaration of Competing Interest N.I. receives research support from Kyowa Kirin co. ltd. The other authors (N.H., H.K.) have nothing to disclose. 2. Endocr Rev. 2019 Aug 1;40(4):1109-1151. doi: 10.1210/er.2018-00126. Skeletal and Extraskeletal Actions of Vitamin D: Current Evidence and Outstanding Questions. Bouillon R(1),...

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PubMed Narrative Review Evidence Moderate

Vitamin D and bone health: What vitamin D can and cannot do.

Advances in food and nutrition research | 2024 | Holick MF

[Indexed for MEDLINE] 8. Int J Mol Sci. 2022 Nov 28;23(23):14896. doi: 10.3390/ijms232314896. Osteomalacia Is Not a Single Disease. Cianferotti L(1). Author information: (1)Bone Metabolic Diseases Unit, Department of Experimental and Biomedical Sciences, University Hospital of Florence, University of Florence, 50139 Florence, Italy. Among bone-material qualities, mineralization...

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PubMed Narrative Review Evidence Moderate

Phosphatonins: From Discovery to Therapeutics.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists | 2023 | Kritmetapak K, Kumar R

[Indexed for MEDLINE] 10. Curr Osteoporos Rep. 2012 Jun;10(2):151-9. doi: 10.1007/s11914-012-0098-z. Vitamin D and bone. Bikle DD(1). Author information: (1)University of California, San Francisco, San Francisco, CA, USA. Daniel.bikle@ucsf.edu All cells comprising the skeleton-chondrocytes, osteoblasts, and osteoclasts-contain both the vitamin D receptor and the enzyme CYP27B1...

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PubMed Narrative Review Evidence Moderate

Osteomalacia Is Not a Single Disease.

International journal of molecular sciences | 2022 | Cianferotti L

[Indexed for MEDLINE] Conflict of interest statement: The author declares no conflict of interest with respect to this paper. 9. Endocr Pract. 2023 Jan;29(1):69-79. doi: 10.1016/j.eprac.2022.09.007. Epub 2022 Oct 7. Phosphatonins: From Discovery to Therapeutics. Kritmetapak K(1), Kumar R(2). Author information: (1)Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand....

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PubMed Narrative Review Evidence Moderate

Skeletal and extraskeletal disorders of biomineralization.

Nature reviews. Endocrinology | 2022 | Collins MT, Marcucci G, Anders HJ, Beltrami G

[Indexed for MEDLINE] 19. Annu Rev Nutr. 1984;4:471-91. doi: 10.1146/annurev.nu.04.070184.002351. Calcium and osteoporosis. Avioli LV. It has become increasingly apparent that the pathogenesis of osteoporosis is complex, poorly understood, and ill-defined. Calcium deficiency and/or calcium malabsorption and the homeostatic response to this biological insult may ultimately prove...

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PubMed Narrative Review Evidence Moderate

FGF23-related hypophosphatemic rickets/osteomalacia: diagnosis and new treatment.

Journal of molecular endocrinology | 2021 | Fukumoto S

[Indexed for MEDLINE] 14. Ann Ital Med Int. 1991 Oct-Dec;6(4 Pt 2):476-82. The osteomalacias. Caniggia A(1). Author information: (1)Clinica Medica nell'Università degli Studi di Siena, Italy. Osteomalacia is characterized by large osteoid seams and a preserved volume of bone trabeculae. The mineralization of newly formed bone requires adequate concentrations of calcium and phos...

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PubMed Narrative Review Evidence Moderate

Mineralized tissues in hypophosphatemic rickets.

Pediatric nephrology (Berlin, Germany) | 2020 | Robinson ME, AlQuorain H, Murshed M, Rauch F

[Indexed for MEDLINE] 7. Adv Food Nutr Res. 2024;109:43-66. doi: 10.1016/bs.afnr.2024.04.002. Epub 2024 May 16. Vitamin D and bone health: What vitamin D can and cannot do. Holick MF(1). Author information: (1)Section of Endocrinology, Diabetes, Nutrition and Weight Management, Department of Medicine, Boston University School of Medicine, Boston, MA, United States. Electronic a...

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PubMed Narrative Review Evidence Moderate

Skeletal and Extraskeletal Actions of Vitamin D: Current Evidence and Outstanding Questions.

Endocrine reviews | 2019 | Bouillon R, Marcocci C, Carmeliet G, Bikle D

[Indexed for MEDLINE] 3. Best Pract Res Clin Endocrinol Metab. 2011 Aug;25(4):585-91. doi: 10.1016/j.beem.2011.05.002. The effect of vitamin D on bone and osteoporosis. Lips P(1), van Schoor NM. Author information: (1)Endocrine Section, Department of Internal Medicine, VU University Medical Center, Amsterdam, The Netherlands. p.lips@vumc.nl The main effect of the active vitamin...

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PubMed Narrative Review Evidence Moderate

Burosumab: First Global Approval.

Drugs | 2018 | Lamb YN

[Indexed for MEDLINE] 13. J Mol Endocrinol. 2021 Feb;66(2):R57-R65. doi: 10.1530/JME-20-0089. FGF23-related hypophosphatemic rickets/osteomalacia: diagnosis and new treatment. Fukumoto S(1). Author information: (1)Fujii Memorial Institute of Medical Sciences, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Tokushima, Japan. FGF23 is a phosphaturic hormo...

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PubMed Narrative Review Evidence Moderate

Vitamin D and bone.

Current osteoporosis reports | 2012 | Bikle DD

[Indexed for MEDLINE] Conflict of interest statement: Disclosure Conflicts of interest: D.D. Bikle: has received grant support from the National Institutes of Health (RO1 DK054793, AR055924, and AR050023); and receives loyalties from Lange textbook chapter. 11. Am J Surg Pathol. 1989 Jul;13(7):588-99. doi: 10.1097/00000478-198907000-00007. Tumor-induced osteomalacia and rickets...

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PubMed Narrative Review Evidence Moderate

The effect of vitamin D on bone and osteoporosis.

Best practice & research. Clinical endocrinology & metabolism | 2011 | Lips P, van Schoor NM

[Indexed for MEDLINE] 4. Vnitr Lek. 2023 Summer;69(4):254-260. doi: 10.36290/vnl.2023.048. [Osteomalacia]. [Article in Czech] Rosa J. Osteomalacia with characteristic histomorphometric, radiographic, laboratory and clinical features is a prominent syndrome of disturbed bone mineralisation in adulthood. From an etiological point of view, osteomalacia is usually caused by substra...

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PubMed Original Article Evidence Unclassified

[Osteomalacia].

Vnitrni lekarstvi | 2023 | Rosa J

[Indexed for MEDLINE] 5. Baillieres Clin Endocrinol Metab. 1997 Apr;11(1):145-63. doi: 10.1016/s0950-351x(97)80569-1. Osteomalacia. Francis RM(1), Selby PL. Author information: (1)University of Newcastle upon Tyne, UK. Osteomalacia is a generalized bone disorder characterized by impairment of mineralization, leading to accumulation of unmineralized matrix or osteoid in the skel...

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PubMed Narrative Review Evidence Moderate

[Drug-induced osteomalacia].

Clinical calcium | 2007 | Sato K

[Indexed for MEDLINE] 16. Biomolecules. 2025 Sep 15;15(9):1321. doi: 10.3390/biom15091321. Approach to a Child with Hypophosphatemia. Antonowicz A(1), Lipiński P(2), Popow M(3), Skrzypczyk P(1). Author information: (1)Department of Pediatrics and Nephrology, Medical University of Warsaw, 02-091 Warsaw, Poland. (2)Institute of Clinical Sciences, Maria Skłodowska-Curie Medical Ac...

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PubMed Narrative Review Evidence Moderate

Imaging of renal osteodystrophy.

European journal of radiology | 2003 | Jevtic V

[Indexed for MEDLINE] 18. Nat Rev Endocrinol. 2022 Aug;18(8):473-489. doi: 10.1038/s41574-022-00682-7. Epub 2022 May 16. Skeletal and extraskeletal disorders of biomineralization. Collins MT(#)(1), Marcucci G(#)(2), Anders HJ(3), Beltrami G(4), Cauley JA(5), Ebeling PR(6), Kumar R(7), Linglart A(8), Sangiorgi L(9), Towler DA(10), Weston R(11), Whyte MP(12)(13), Brandi ML(14), C...

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PubMed Narrative Review Evidence Moderate

Osteomalacia.

Bailliere's clinical endocrinology and metabolism | 1997 | Francis RM, Selby PL

[Indexed for MEDLINE] 6. Pediatr Nephrol. 2020 Oct;35(10):1843-1854. doi: 10.1007/s00467-019-04290-y. Epub 2019 Aug 8. Mineralized tissues in hypophosphatemic rickets. Robinson ME(1), AlQuorain H(1), Murshed M(1), Rauch F(2). Author information: (1)Shriners Hospital for Children and McGill University, 1003 Boulevard Decarie, Montreal, Québec, H4A 0A9, Canada. (2)Shriners Hospit...

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PubMed Narrative Review Evidence Moderate

Calcium and osteoporosis.

Annual review of nutrition | 1984 | Avioli LV

[Indexed for MEDLINE] 20. Arq Bras Endocrinol Metabol. 2006 Aug;50(4):802-13. doi: 10.1590/s0004-27302006000400025. Hypophosphatemic rickets and osteomalacia. de Menezes Filho H(1), de Castro LC, Damiani D. Author information: (1)Instituto da Criança, Hospital das Clínicas, Medical School, São Paulo University, São Paulo, SP, Brazil. The hypophosphatemic conditions that interfe...

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PubMed Case Report / Series Evidence Low

Tumor-induced osteomalacia and rickets.

The American journal of surgical pathology | 1989 | Nuovo MA, Dorfman HD, Sun CC, Chalew SA

[Indexed for MEDLINE] 12. Drugs. 2018 Apr;78(6):707-714. doi: 10.1007/s40265-018-0905-7. Burosumab: First Global Approval. Lamb YN(1). Author information: (1)Springer, Private Bag 65901, Mairangi Bay, Auckland, 0754, New Zealand. dru@adis.com. Burosumab (Crysvita®; Kyowa Hakko Kirin Co., Ltd. and Ultragenyx Pharmaceutical Inc.) is a fully human monoclonal antibody directed at f...

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PubMed Original Article Evidence Unclassified

The osteomalacias.

Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna | 1991 | Caniggia A

[Indexed for MEDLINE] 15. Clin Calcium. 2007 Oct;17(10):1536-42. [Drug-induced osteomalacia]. [Article in Japanese] Sato K(1). Author information: (1)Tokyo Women's Medical University, Institute of Clinical Endocrinology. In our country, calcium- or phosphate-deficient rickets/osteomalacia due to malnutrition are scarcely reported. However, osteomalacia induced by drugs, such as...

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