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Evidence Search

Search reputable indexed orthopaedic literature from multiple scholarly sources, classify the evidence, and link papers directly to wiki topics and cases.

Sources: PubMed, Europe PMC, Crossref

Linking results to Wiki: Osteosarcoma — Diagnosis & Treatment
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Results are classified automatically from source metadata across PubMed, Europe PMC, and Crossref.
Crossref PubMed
Crossref Review Article Evidence Moderate

Primary Cardiac Osteosarcoma: Epidemiology, Diagnosis, and Management — A Narrative Review

Orthopedic Reviews | 2025 | Tommy Li, Eric Nguyen, Jamal Hasoon, Ali Khalifa

Purpose Primary cardiac sarcomas are exceedingly rare, with a very low incidence in the general population. A variety of sarcoma subtypes can originate in the heart, including angiosarcoma, rhabdomyosarcoma, leiomyosarcoma, fibrosarcoma, and osteosarcoma. These tumors are typically classified based on histological characteristics, most often determined following surgical excisi...

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PubMed Narrative Review Evidence Moderate

Management of osteosarcoma of the head and neck.

Current opinion in otolaryngology & head and neck surgery | 2023 | Sharin F, Pai A, Mair M

[Indexed for MEDLINE] 11. Orthopadie (Heidelb). 2023 Jun;52(6):509-522. doi: 10.1007/s00132-023-04387-1. Epub 2023 Jun 6. [Primary malignant bone tumors]. [Article in German; Abstract available in German from the publisher] Funovics PT(1). Author information: (1)Universitätsklinik für Orthopädie und Unfallchirurgie, Klinische Abteilung für Orthopädie, Medizinische Universität W...

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PubMed Narrative Review Evidence Moderate

Return to Sports and Activity in Tumor Orthopaedics.

Zeitschrift fur Orthopadie und Unfallchirurgie | 2023 | Mester B, Guder W, Streitbürger A, Schoepp C

[Indexed for MEDLINE] Conflict of interest statement: Die Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht. 20. Eur J Orthop Surg Traumatol. 2014 Dec;24(8):1351-6. doi: 10.1007/s00590-013-1312-0. Epub 2013 Sep 6. Palliative embolization for osteosarcoma. Mavrogenis AF(1), Rossi G, Rimondi E, Calabrò T, Papagelopoulos PJ, Ruggieri P. Author information: (1)First...

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PubMed Narrative Review Evidence Moderate

Immunotherapy for osteosarcoma: Fundamental mechanism, rationale, and recent breakthroughs.

Cancer letters | 2021 | Chen C, Xie L, Ren T, Huang Y

[Indexed for MEDLINE] 2. J Am Acad Orthop Surg. 2009 Aug;17(8):515-27. doi: 10.5435/00124635-200908000-00005. Osteosarcoma. Messerschmitt PJ(1), Garcia RM, Abdul-Karim FW, Greenfield EM, Getty PJ. Author information: (1)Department of Orthopaedic Surgery, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH 44106, USA. Osteosarcoma, the most c...

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PubMed Narrative Review Evidence Moderate

Recent Advances in Nanotechnology-Based Diagnosis and Treatments of Human Osteosarcoma.

Biosensors | 2021 | Barani M, Mukhtar M, Rahdar A, Sargazi S

[Indexed for MEDLINE] Conflict of interest statement: The authors declare no conflict of interest. 19. Z Orthop Unfall. 2023 Aug;161(4):385-395. doi: 10.1055/a-1676-5266. Epub 2021 Dec 8. Return to Sports and Activity in Tumor Orthopaedics. [Article in English, German; Abstract available in German from the publisher] Mester B(1), Guder W(2), Streitbürger A(2), Schoepp C(3), Not...

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PubMed Narrative Review Evidence Moderate

Understanding osteosarcomas.

JAAPA : official journal of the American Academy of Physician Assistants | 2018 | Simpson E, Brown HL

[Indexed for MEDLINE] 4. Cancer Treat Res. 2023;185:127-139. doi: 10.1007/978-3-031-27156-4_8. Osteosarcoma and Its Advancement. Basit Q(1), Qazi HS(2), Tanveer S(3). Author information: (1)Orthopedic Sports Medicine Center, Al Mana General Hospital, Jubail, Saudi Arabia. qazibasit_cs@hotmail.com. (2)Hospital of Dalian Medical University, Dalian, Lionning, China. (3)FCPS Genera...

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PubMed Narrative Review Evidence Moderate

Knochensarkome.

Zeitschrift fur Orthopadie und Unfallchirurgie | 2018 | Hardes J, Gosheger G, Budny T

[Indexed for MEDLINE] Conflict of interest statement: Die Autoren geben an, dass kein Interessenkonflikt besteht. 8. Bull Hosp Jt Dis Orthop Inst. 1991 Spring;51(1):1-11. Osteosarcoma. Campanacci M(1), Ruggieri P. Author information: (1)University of Bologna, Italy. Dr. Campanacci was the 1990 Sir Robert Jones Lecturer of the Hospital for Joint Diseases Orthopaedic Institute. T...

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PubMed Narrative Review Evidence Moderate

The pharmacogenomics of osteosarcoma.

The pharmacogenomics journal | 2017 | Serra M, Hattinger CM

[Indexed for MEDLINE] 7. Z Orthop Unfall. 2018 Feb;156(1):105-124. doi: 10.1055/s-0043-117905. Epub 2018 Feb 22. Knochensarkome. [Article in German; Abstract available in German from the publisher] Hardes J, Gosheger G, Budny T. Bone sarcomas are extremely rare representing approximately 0.2% among all cancer types. Due to the rarity of these tumors both the patients and the ph...

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PubMed Narrative Review Evidence Moderate

Multidisciplinary approach to osteosarcoma.

Acta orthopaedica Belgica | 2016 | Biazzo A, De Paolis M

[Indexed for MEDLINE] 10. Curr Opin Otolaryngol Head Neck Surg. 2023 Aug 1;31(4):269-275. doi: 10.1097/MOO.0000000000000900. Epub 2023 May 3. Management of osteosarcoma of the head and neck. Sharin F(1), Pai A(2), Mair M(1). Author information: (1)University hospital of Leicester, Leicester, UK. (2)HCG Hospital, Mumbai, India. PURPOSE OF REVIEW: There is no clear consensus guid...

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PubMed Narrative Review Evidence Moderate

Sarcomas of Soft Tissue and Bone.

Progress in tumor research | 2016 | Ferrari A, Dirksen U, Bielack S

[Indexed for MEDLINE] 17. Adv Exp Med Biol. 2014;804:291-304. doi: 10.1007/978-3-319-04843-7_16. Bone-seeking radiopharmaceuticals as targeted agents of osteosarcoma: samarium-153-EDTMP and radium-223. Anderson PM(1), Subbiah V, Rohren E. Author information: (1)Levine Children's Hospital, Charlotte, NC, USA, peter.anderson@carolinashealthcare.org. Osteosarcoma is a cancer chara...

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PubMed Narrative Review Evidence Moderate

Chondrosarcomas of the head and neck.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery | 2014 | Coca-Pelaz A, Rodrigo JP, Triantafyllou A, Hunt JL

[Indexed for MEDLINE] 14. Curr Opin Pediatr. 2009 Jun;21(3):365-72. doi: 10.1097/MOP.0b013e32832b1111. Bone tumors: osteosarcoma and Ewing's sarcoma. Heare T(1), Hensley MA, Dell'Orfano S. Author information: (1)Musculoskeletal Tumor Program, Department of Orthopaedic Surgery, University of Colorado, The Children's Hospital, Denver, CO, USA. heare.travis@tchden.org PURPOSE OF R...

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PubMed Narrative Review Evidence Moderate

Bone-seeking radiopharmaceuticals as targeted agents of osteosarcoma: samarium-153-EDTMP and radium-223.

Advances in experimental medicine and biology | 2014 | Anderson PM, Subbiah V, Rohren E

[Indexed for MEDLINE] 18. Biosensors (Basel). 2021 Feb 20;11(2):55. doi: 10.3390/bios11020055. Recent Advances in Nanotechnology-Based Diagnosis and Treatments of Human Osteosarcoma. Barani M(1), Mukhtar M(2), Rahdar A(3), Sargazi S(4), Pandey S(5)(6), Kang M(6). Author information: (1)Department of Chemistry, Shahid Bahonar University of Kerman, Kerman 76169-14111, Iran. (2)Fa...

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PubMed Narrative Review Evidence Moderate

Pediatric osteogenic sarcoma.

Current opinion in pediatrics | 2010 | Kim HJ, Chalmers PN, Morris CD

[Indexed for MEDLINE] 6. Pharmacogenomics J. 2017 Jan;17(1):11-20. doi: 10.1038/tpj.2016.45. Epub 2016 May 31. The pharmacogenomics of osteosarcoma. Serra M(1), Hattinger CM(1). Author information: (1)Laboratory of Experimental Oncology, Orthopaedic Rizzoli Institute, Bologna, Italy. Osteosarcoma (OS), the most common malignant tumor of bone, is presently treated with multidrug...

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PubMed Narrative Review Evidence Moderate

Osteosarcoma.

The Journal of the American Academy of Orthopaedic Surgeons | 2009 | Messerschmitt PJ, Garcia RM, Abdul-Karim FW, Greenfield EM

[Indexed for MEDLINE] 3. JAAPA. 2018 Aug;31(8):15-19. doi: 10.1097/01.JAA.0000541477.24116.8d. Understanding osteosarcomas. Simpson E(1), Brown HL. Author information: (1)At the time this article was written, Emily Simpson was a student in the PA program at Mercer University in Atlanta, Ga. She now practices urgent care medicine with Georgia Emergency Associates in Savannah, Ga...

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PubMed Narrative Review Evidence Moderate

Bone tumors: osteosarcoma and Ewing's sarcoma.

Current opinion in pediatrics | 2009 | Heare T, Hensley MA, Dell'Orfano S

[Indexed for MEDLINE] 15. Ital J Orthop Traumatol. 1988 Mar;14(1):5-13. Vertebral osteosarcoma. Tigani D(1), Pignatti G, Picci P, Savini R, Campanacci M. Author information: (1)I Clinica Ortopedica dell'Università, Istituto Rizzoli, Bologna. A review of the total number of cases of osteosarcoma referred to the Tumour Centre at the Rizzoli Orthopaedic Institute between 1904 and...

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PubMed Original Article Evidence Unclassified

Osteosarcoma and Its Advancement.

Cancer treatment and research | 2023 | Basit Q, Qazi HS, Tanveer S

[Indexed for MEDLINE] 5. Curr Opin Pediatr. 2010 Feb;22(1):61-6. doi: 10.1097/MOP.0b013e328334581f. Pediatric osteogenic sarcoma. Kim HJ(1), Chalmers PN, Morris CD. Author information: (1)Hospital for Special Surgery, New York, NY, USA. kimh@hss.edu PURPOSE OF REVIEW: Osteogenic sarcoma, also known as osteosarcoma, is a primary malignancy of the bone in which spindle cells prod...

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PubMed Original Article Evidence Unclassified

[Primary malignant bone tumors].

Orthopadie (Heidelberg, Germany) | 2023 | Funovics PT

[Indexed for MEDLINE] 12. Semin Surg Oncol. 1999 Mar;16(2):173-83. doi: 10.1002/(sici)1098-2388(199903)16:23.0.co;2-g. Pediatric bone tumors. Yaw KM(1). Author information: (1)University of Pittsburgh School of Medicine, Pennsylvania, USA. kyaw@uoi.upmc.edu Although osteosarcoma and Ewing's sarcoma are quite rare, they are the only primary skeletal malignancies that occur with...

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PubMed Narrative Review Evidence Moderate

Pediatric bone tumors.

Seminars in surgical oncology | 1999 | Yaw KM

[Indexed for MEDLINE] 13. Eur Arch Otorhinolaryngol. 2014 Oct;271(10):2601-9. doi: 10.1007/s00405-013-2807-3. Epub 2013 Nov 10. Chondrosarcomas of the head and neck. Coca-Pelaz A(1), Rodrigo JP, Triantafyllou A, Hunt JL, Fernández-Miranda JC, Strojan P, de Bree R, Rinaldo A, Takes RP, Ferlito A. Author information: (1)Department of Otolaryngology, Hospital Universitario Central...

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PubMed Narrative Review Evidence Moderate

Osteosarcoma.

Bulletin of the Hospital for Joint Diseases Orthopaedic Institute | 1991 | Campanacci M, Ruggieri P

[Indexed for MEDLINE] 9. Acta Orthop Belg. 2016 Dec;82(4):690-698. Multidisciplinary approach to osteosarcoma. Biazzo A, De Paolis M. Osteosarcoma is a malignant bone tumor composed of mesenchymal cells producing osteoid and immature bone. Osteosarcoma is the most frequent primary malignant bone tumor, if we excluded myeloma, a haematologic disease. The incidence of osteosarcom...

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PubMed Original Article Evidence Unclassified

Vertebral osteosarcoma.

Italian journal of orthopaedics and traumatology | 1988 | Tigani D, Pignatti G, Picci P, Savini R

[Indexed for MEDLINE] 16. Prog Tumor Res. 2016;43:128-41. doi: 10.1159/000447083. Epub 2016 Sep 5. Sarcomas of Soft Tissue and Bone. Ferrari A, Dirksen U, Bielack S. The definition of soft tissue and bone sarcomas include a large group of several heterogeneous subtypes of mesenchymal origin that may occur at any age. Among the different sarcomas, rhabdomyosarcoma, synovial sarc...

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