Orthonotes
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Evidence Search

Search reputable indexed orthopaedic literature from multiple scholarly sources, classify the evidence, and link papers directly to wiki topics and cases.

Sources: PubMed, Europe PMC, Crossref

Linking results to Wiki: Polytrauma — Damage Control vs Early Total Care
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Results are classified automatically from source metadata across PubMed, Europe PMC, and Crossref.
PubMed Crossref
PubMed Randomized Controlled Trial Evidence High

Results of the CONTROL trial: efficacy and safety of recombinant activated Factor VII in the management of refractory traumatic hemorrhage.

The Journal of trauma | 2010 | Hauser CJ, Boffard K, Dutton R, Bernard GR

[Indexed for MEDLINE] 13. Injury. 2013 Feb;44(2):221-5. doi: 10.1016/j.injury.2012.09.011. Epub 2012 Oct 4. Increased morbidity and mortality after bilateral femoral shaft fractures: myth or reality in the era of damage control? Kobbe P(1), Micansky F, Lichte P, Sellei RM, Pfeifer R, Dombroski D, Lefering R, Pape HC; TraumaRegister DGU. Author information: (1)Department of Orth...

PubMed Narrative Review Evidence Moderate

Animal models to assess the local and systemic effects of nailing: review of the literature and considerations for future studies.

The journal of trauma and acute care surgery | 2014 | Hildebrand F, Andruszkow H, Barkatali BM, Pfeifer R

[Indexed for MEDLINE] 7. Chirurg. 2013 Sep;84(9):759-63. doi: 10.1007/s00104-013-2478-z. [Operative treatment strategies for multiple trauma patients : early total care versus damage control]. [Article in German] Klüter T(1), Lippross S, Oestern S, Weuster M, Seekamp A. Author information: (1)Klinik für Unfallchirurgie (Traumatologie), Traumazentrum Nord, Universitätsklinikum S...

PubMed Narrative Review Evidence Moderate

[Operative treatment strategies for multiple trauma patients : early total care versus damage control].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen | 2013 | Klüter T, Lippross S, Oestern S, Weuster M

[Indexed for MEDLINE] 8. J Trauma. 2009 Sep;67(3):602-5. doi: 10.1097/TA.0b013e3181aa21c0. Safety and efficacy of damage control external fixation versus early definitive stabilization for femoral shaft fractures in the multiple-injured patient. Tuttle MS(1), Smith WR, Williams AE, Agudelo JF, Hartshorn CJ, Moore EE, Morgan SJ. Author information: (1)Department of Orthopaedic S...

PubMed Cohort / Comparative Study Evidence Moderate

Increased morbidity and mortality after bilateral femoral shaft fractures: myth or reality in the era of damage control?

Injury | 2013 | Kobbe P, Micansky F, Lichte P, Sellei RM

[Indexed for MEDLINE] 14. J Trauma. 2005 Mar;58(3):446-52; discussion 452-4. doi: 10.1097/01.ta.0000153942.28015.77. Alterations in the systemic inflammatory response after early total care and damage control procedures for femoral shaft fracture in severely injured patients. Harwood PJ(1), Giannoudis PV, van Griensven M, Krettek C, Pape HC. Author information: (1)Department of...

Crossref Journal Article Evidence Unclassified

Caught in the Crossroads: Damage Control Orthopedics versus Early Total Care for Polytrauma in the Indian Scenario

Annals of African Medicine | 2025 | Amit Lakhani, Udit Choubey, Kanishk Aggarwal, Yash Vardhan Trivedi

Abstract Polytrauma patients are defined by the Berlin Consensus as those with severe injuries across multiple regions and require complex, adaptable treatment approaches to address both immediate and long-term needs of the patient, while considering the resource availability. This review evaluates early total care (ETC), which attempts early definitive fixation, against damage...

PubMed Original Article Evidence Unclassified

Compact Arterial Monitoring Device Use in Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA): A Simple Validation Study in Swine.

Cureus | 2024 | Lussier G, Evans AJ, Houston I, Wilsnack A

Conflict of interest statement: Human subjects: All authors have confirmed that this study did not involve human participants or tissue. Animal subjects: Institutional Animal Care and Use Committee (IACUC): The research protocol was approved by the IACUC of the Uniformed Services University of the Health Sciences. Ethical approval and Trial Registration Details Per Reviewer Req...

PubMed Original Article Evidence Unclassified

Damage Control Orthopaedics Induced Less Trauma-Induced Coagulopathy than Early Total Care in a Porcine Polytrauma Model.

European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes | 2024 | Mert Ü, Groven RVM, Greven J, He Z

[Indexed for MEDLINE] 3. J Trauma. 2005 Aug;59(2):409-16; discussion 417. doi: 10.1097/01.ta.0000175088.29170.3e. Damage control orthopedics in patients with multiple injuries is effective, time saving, and safe. Taeger G(1), Ruchholtz S, Waydhas C, Lewan U, Schmidt B, Nast-Kolb D. Author information: (1)Department of Trauma Surgery, University Hospital Essen, Essen, Germany. g...

Crossref Journal Article Evidence Unclassified

A PROSPECTIVE COMPARATIVE STUDY OF EARLY TOTAL CARE VS DAMAGE CONTROL ORTHOPEDICS IN POLY-TRAUMATIZED PATIENTS

INDIAN JOURNAL OF APPLIED RESEARCH | 2024 | Sayaji Bhamre, Salil Ibrahim

Aim: To compare the efficacy and treatment outcomes of early total care (ETC) and Damage control orthopedics in management of poly traumatic patients A total of 64 admitted poly-traumatized patients were Materials and methods: studied in between February 2022 to June 2023. The patients presented with femoral and /or tibial shaft fractures and associated multiple injuries. The t...

PubMed Original Article Evidence Unclassified

Early total care or damage control orthopaedics for major fractures ? Results of propensity score matching for early definitive versus early temporary fixation based on data from the trauma registry of the German Trauma Society (TraumaRegister DGU(®)).

European journal of trauma and emergency surgery : official publication of the European Trauma Society | 2023 | von Lübken F, Prause S, Lang P, Friemert BD

[Indexed for MEDLINE] Conflict of interest statement: The authors declare that they have no conflict of interest. 5. Trauma Surg Acute Care Open. 2023 Nov 20;8(1):e001160. doi: 10.1136/tsaco-2023-001160. eCollection 2023. Achieving balanced transfusion early in critically bleeding trauma patients: an observational study exploring the effect of attending trauma surgical presence...

PubMed Original Article Evidence Unclassified

Achieving balanced transfusion early in critically bleeding trauma patients: an observational study exploring the effect of attending trauma surgical presence during resuscitation.

Trauma surgery & acute care open | 2023 | Gaski IA, Naess PA, Baksaas-Aasen K, Skaga NO

Conflict of interest statement: Competing interests: None declared. 6. J Trauma Acute Care Surg. 2014 Jun;76(6):1495-506. doi: 10.1097/TA.0000000000000236. Animal models to assess the local and systemic effects of nailing: review of the literature and considerations for future studies. Hildebrand F(1), Andruszkow H, Barkatali BM, Pfeifer R, Lichte P, Kobbe P, Pape HC. Author in...

PubMed Original Article Evidence Unclassified

Impact of a Femoral Fracture on Outcome after Traumatic Brain Injury-A Matched-Pair Analysis of the TraumaRegister DGU(®).

Journal of clinical medicine | 2023 | Paul MM, Mieden HJ, Lefering R, Kupczyk EK

Conflict of interest statement: R.L. and his institution (IFOM) have an ongoing service agreement with AUC GmbH, the holder of the TraumaRegister DGU®. This includes statistical consultations relating to scientific analyses. All other authors declare no conflict of interest. 10. Eur J Trauma Emerg Surg. 2022 Jun;48(3):1769-1778. doi: 10.1007/s00068-020-01599-4. Epub 2021 Feb 15...

PubMed Original Article Evidence Unclassified

Strategies for the treatment of femoral fractures in severely injured patients: trends in over two decades from the TraumaRegister DGU(®).

European journal of trauma and emergency surgery : official publication of the European Trauma Society | 2022 | Bläsius FM, Laubach M, Andruszkow H, Lichte P

[Indexed for MEDLINE] Conflict of interest statement: RL declares that his institution receives an ongoing support from AUC, the data holder of TR-DGU, which includes statistical support of data analysis from registry data. 11. Orthop Traumatol Surg Res. 2021 May;107(3):102864. doi: 10.1016/j.otsr.2021.102864. Epub 2021 Feb 20. Bilateral femoral shaft fracture in polytrauma pat...

PubMed Original Article Evidence Unclassified

Bilateral femoral shaft fracture in polytrauma patients: Can intramedullary nailing be done on an emergency basis?

Orthopaedics & traumatology, surgery & research : OTSR | 2021 | Denis-Aubrée P, Dukan R, Karam K, Molina V

[Indexed for MEDLINE] 12. J Trauma. 2010 Sep;69(3):489-500. doi: 10.1097/TA.0b013e3181edf36e. Results of the CONTROL trial: efficacy and safety of recombinant activated Factor VII in the management of refractory traumatic hemorrhage. Hauser CJ(1), Boffard K, Dutton R, Bernard GR, Croce MA, Holcomb JB, Leppaniemi A, Parr M, Vincent JL, Tortella BJ, Dimsits J, Bouillon B; CONTROL...

PubMed Original Article Evidence Unclassified

Population-based epidemiology of femur shaft fractures.

The journal of trauma and acute care surgery | 2013 | Enninghorst N, McDougall D, Evans JA, Sisak K

[Indexed for MEDLINE] 16. J Trauma. 2002 Sep;53(3):452-61; discussion 461-2. doi: 10.1097/00005373-200209000-00010. Changes in the management of femoral shaft fractures in polytrauma patients: from early total care to damage control orthopedic surgery. Pape HC(1), Hildebrand F, Pertschy S, Zelle B, Garapati R, Grimme K, Krettek C, Reed RL 2nd. Author information: (1)Department...

Crossref Journal Article Evidence Unclassified

Early Total Care versus Damage Control: Current Concepts in the Orthopedic Care of Polytrauma Patients

ISRN Orthopedics | 2013 | Ratto Nicola

The management of the polytraumatized orthopedic patient remains a challenging issue. In recent years many efforts have been made to develop rescue techniques and to promote guidelines for the management of these patients. Currently controversies persist between two orthopedic approaches: the Early Total Care and the Damage Control Orthopedics. An overview of the current litera...

PubMed Original Article Evidence Unclassified

Safety and efficacy of damage control external fixation versus early definitive stabilization for femoral shaft fractures in the multiple-injured patient.

The Journal of trauma | 2009 | Tuttle MS, Smith WR, Williams AE, Agudelo JF

[Indexed for MEDLINE] 9. J Clin Med. 2023 May 31;12(11):3802. doi: 10.3390/jcm12113802. Impact of a Femoral Fracture on Outcome after Traumatic Brain Injury-A Matched-Pair Analysis of the TraumaRegister DGU(®). Paul MM(1)(2)(3), Mieden HJ(1), Lefering R(4), Kupczyk EK(1), Jordan MC(1), Gilbert F(5), Meffert RH(1), Sirén AL(2)(3), Hoelscher-Doht S(1). Author information: (1)Depa...

PubMed Original Article Evidence Unclassified

Damage control orthopedics in patients with multiple injuries is effective, time saving, and safe.

The Journal of trauma | 2005 | Taeger G, Ruchholtz S, Waydhas C, Lewan U

[Indexed for MEDLINE] 4. Eur J Trauma Emerg Surg. 2023 Aug;49(4):1933-1946. doi: 10.1007/s00068-022-02215-3. Epub 2023 Jan 20. Early total care or damage control orthopaedics for major fractures ? Results of propensity score matching for early definitive versus early temporary fixation based on data from the trauma registry of the German Trauma Society (TraumaRegister DGU(®))....

PubMed Original Article Evidence Unclassified

Alterations in the systemic inflammatory response after early total care and damage control procedures for femoral shaft fracture in severely injured patients.

The Journal of trauma | 2005 | Harwood PJ, Giannoudis PV, van Griensven M, Krettek C

[Indexed for MEDLINE] 15. J Trauma Acute Care Surg. 2013 Jun;74(6):1516-20. doi: 10.1097/TA.0b013e31828c3dc9. Population-based epidemiology of femur shaft fractures. Enninghorst N(1), McDougall D, Evans JA, Sisak K, Balogh ZJ. Author information: (1)Division of Surgery, Department of Traumatology, John Hunter Hospital and University of Newcastle, Newcastle, New South Wales, Aus...

PubMed Original Article Evidence Unclassified

Changes in the management of femoral shaft fractures in polytrauma patients: from early total care to damage control orthopedic surgery.

The Journal of trauma | 2002 | Pape HC, Hildebrand F, Pertschy S, Zelle B

[Indexed for MEDLINE] 17. Eur J Trauma Emerg Surg. 2019 Oct;45(5):801-808. doi: 10.1007/s00068-019-01092-7. Epub 2019 Feb 13. Surgical treatment strategies in pediatric trauma patients: ETC vs. DCO-an analysis of 316 pediatric trauma patients from the TraumaRegister DGU(®). Horst K(1), Andruszkow H(2), Weber CD(2), Pishnamaz M(2), Knobe M(2), Bläsius FM(2), Lichte P(2), Leferin...