Evidence Search

The growth plate: Zonal architecture, plasticity, and endocrine control of linear growth.

Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society | 2026 | Ostria CB, Yakar S

[Indexed for MEDLINE] Conflict of interest statement: Declaration of competing interest The authors declare no competing interests. 15. Bone Res. 2023 Aug 22;11(1):46. doi: 10.1038/s41413-023-00284-7. α-parvin controls chondrocyte column formation and regulates long bone development. Yuan J(1)(2), Guo L(3), Wang J(3), Zhou Z(4), Wu C(5)(6). Author information: (1)Guangdong Prov...

miRNA-based regulation in growth plate cartilage: mechanisms, targets, and therapeutic potential.

Frontiers in endocrinology | 2025 | Thakore P, Delany AM

[Indexed for MEDLINE] Conflict of interest statement: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. 5. Folia Histochem Cytobiol. 2009;47(1):5-16. doi: 10.2478/v10042-009-0007-1. Morphology and physiology of the epiphyseal growth plate. Burdan F(1), Szum...

Zebrafish endochondral growth zones as they relate to human bone size, shape and disease.

Frontiers in endocrinology | 2022 | Le Pabic P, Dranow DB, Hoyle DJ, Schilling TF

[Indexed for MEDLINE] Conflict of interest statement: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. 7. J Mol Endocrinol. 2018 Jul;61(1):T115-T137. doi: 10.1530/JME-17-0298. Epub 2018 Apr 6. Insulin-like growth factors: actions on the skeleton. Yakar S(1...

Molecular Mechanism of Induction of Bone Growth by the C-Type Natriuretic Peptide.

International journal of molecular sciences | 2022 | Rintz E, Węgrzyn G, Fujii T, Tomatsu S

[Indexed for MEDLINE] Conflict of interest statement: The authors declare that they have no conflict of interest. 13. Front Endocrinol (Lausanne). 2012 Jan 9;2:113. doi: 10.3389/fendo.2011.00113. eCollection 2011. Genetic regulation of the growth plate. Karimian E(1), Chagin AS, Sävendahl L. Author information: (1)Pediatric Endocrinology Unit, Department of Women's and Children...

Insulin-like growth factors: actions on the skeleton.

Journal of molecular endocrinology | 2018 | Yakar S, Werner H, Rosen CJ

[Indexed for MEDLINE] 8. J Biomech. 2009 Aug 25;42(12):1793-803. doi: 10.1016/j.jbiomech.2009.05.021. Epub 2009 Jun 21. Growth plate mechanics and mechanobiology. A survey of present understanding. Villemure I(1), Stokes IA. Author information: (1)Department of Mechanical Engineering, Ecole Polytechnique of Montreal, Station Centre-Ville, Montréal, Québec, Canada. isabelle.vill...

Imaging Findings of Metabolic Bone Disease.

Radiographics : a review publication of the Radiological Society of North America, Inc | 2016 | Chang CY, Rosenthal DI, Mitchell DM, Handa A

[Indexed for MEDLINE] 10. Bone Joint Res. 2025 Jul 1;14(7):589-600. doi: 10.1302/2046-3758.147.BJR-2024-0347.R1. G-protein-coupled estrogen receptor-1 facilitates chondrocyte proliferation in pubertal epiphyseal growth plate via PTHrP/Ihh regulation. Chou YS(1)(2), Lin SY(1)(2)(3)(4)(5), Chuang SC(1)(2), Shih PY(1)(2), Chen CH(1)(2)(3)(6)(7)(8)(9), Ho ML(1)(2)(10), Chang JK(1)(...

Factors affecting bone growth.

American journal of orthopedics (Belle Mead, N.J.) | 2015 | Gkiatas I, Lykissas M, Kostas-Agnantis I, Korompilias A

[Indexed for MEDLINE] 3. Matrix Biol. 2024 Nov;133:86-102. doi: 10.1016/j.matbio.2024.08.002. Epub 2024 Aug 17. Fibronectin isoforms promote postnatal skeletal development. Dinesh NEH(1), Baratang N(2), Rosseau J(2), Mohapatra R(1), Li L(1), Mahalingam R(3), Tiedemann K(4), Campeau PM(2), Reinhardt DP(5). Author information: (1)Faculty of Medicine and Health Sciences, Departmen...

G-protein-coupled estrogen receptor-1 facilitates chondrocyte proliferation in pubertal epiphyseal growth plate via PTHrP/Ihh regulation.

Bone & joint research | 2025 | Chou YS, Lin SY, Chuang SC, Shih PY

Conflict of interest statement: The authors report support for attending meetings and/or travel from the Regenerative Medicine and Cell Therapy Research Center, Kaohsiung Medical University (KMU-TC112A02), unrelated to this study. 11. J Musculoskelet Neuronal Interact. 2005 Jul-Sep;5(3):194-201. Bone growth in length and width: the Yin and Yang of bone stability. Rauch F(1). Au...

Piezo1 expression in chondrocytes controls endochondral ossification and osteoarthritis development.

Bone research | 2024 | Brylka LJ, Alimy AR, Tschaffon-Müller MEA, Jiang S

[Indexed for MEDLINE] Conflict of interest statement: The authors declare no competing interests. 2. Am J Orthop (Belle Mead NJ). 2015 Feb;44(2):61-7. Factors affecting bone growth. Gkiatas I(1), Lykissas M, Kostas-Agnantis I, Korompilias A, Batistatou A, Beris A. Author information: (1)University of Ioannina, School of Medicine, Division of Orthopaedic Surgery, Ioannina, Greec...

Fibronectin isoforms promote postnatal skeletal development.

Matrix biology : journal of the International Society for Matrix Biology | 2024 | Dinesh NEH, Baratang N, Rosseau J, Mohapatra R

[Indexed for MEDLINE] Conflict of interest statement: Declaration of competing interest The authors declare no competing interests. 4. Front Endocrinol (Lausanne). 2025 Mar 28;16:1530374. doi: 10.3389/fendo.2025.1530374. eCollection 2025. miRNA-based regulation in growth plate cartilage: mechanisms, targets, and therapeutic potential. Thakore P(1), Delany AM(1). Author informat...

Morphology and physiology of the epiphyseal growth plate.

Folia histochemica et cytobiologica | 2009 | Burdan F, Szumiło J, Korobowicz A, Farooquee R

[Indexed for MEDLINE] 6. Front Endocrinol (Lausanne). 2022 Dec 6;13:1060187. doi: 10.3389/fendo.2022.1060187. eCollection 2022. Zebrafish endochondral growth zones as they relate to human bone size, shape and disease. Le Pabic P(1), Dranow DB(2), Hoyle DJ(2), Schilling TF(2). Author information: (1)Department of Biology and Marine Biology, University of North Carolina Wilmingto...

Growth plate mechanics and mechanobiology. A survey of present understanding.

Journal of biomechanics | 2009 | Villemure I, Stokes IA

[Indexed for MEDLINE] 9. Radiographics. 2016 Oct;36(6):1871-1887. doi: 10.1148/rg.2016160004. Imaging Findings of Metabolic Bone Disease. Chang CY(1), Rosenthal DI(1), Mitchell DM(1), Handa A(1), Kattapuram SV(1), Huang AJ(1). Author information: (1)From the Division of Musculoskeletal Imaging and Intervention, Department of Radiology (C.Y.C., D.I.R., S.V.K., A.J.H.), and the P...

α-parvin controls chondrocyte column formation and regulates long bone development.

Bone research | 2023 | Yuan J, Guo L, Wang J, Zhou Z

[Indexed for MEDLINE] Conflict of interest statement: The authors declare no competing interests. 16. Methods Mol Biol. 2021;2245:105-119. doi: 10.1007/978-1-0716-1119-7_8. Laser Capture Microdissection of Mouse Growth Plate Cartilage. Kikani B(1), Lui JC(2). Author information: (1)Section on Growth and Development, Eunice Kennedy Shriver National Institute of Child Health and...

Cross-talk between EGFR and BMP signals regulates chondrocyte maturation during endochondral ossification.

Developmental dynamics : an official publication of the American Association of Anatomists | 2022 | Lees-Shepard JB, Flint K, Fisher M, Omi M

[Indexed for MEDLINE] 19. Bone. 2007 Mar;40(3):577-86. doi: 10.1016/j.bone.2006.10.013. Epub 2006 Dec 13. Fibroblast growth factor expression in the postnatal growth plate. Lazarus JE(1), Hegde A, Andrade AC, Nilsson O, Baron J. Author information: (1)Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bet...

Laser Capture Microdissection of Mouse Growth Plate Cartilage.

Methods in molecular biology (Clifton, N.J.) | 2021 | Kikani B, Lui JC

[Indexed for MEDLINE] 17. Bone. 2015 Jul;76:97-106. doi: 10.1016/j.bone.2015.02.031. Epub 2015 Apr 4. Role of c-Myb in chondrogenesis. Oralová V(1), Matalová E(2), Janečková E(3), Drobná Krejčí E(4), Knopfová L(5), Šnajdr P(4), Tucker AS(6), Veselá I(7), Šmarda J(5), Buchtová M(3). Author information: (1)Institute of Animal Physiology and Genetics CAS, v.v.i., Brno, Czech Repub...

Bone growth in length and width: the Yin and Yang of bone stability.

Journal of musculoskeletal & neuronal interactions | 2005 | Rauch F

[Indexed for MEDLINE] 12. Int J Mol Sci. 2022 May 25;23(11):5916. doi: 10.3390/ijms23115916. Molecular Mechanism of Induction of Bone Growth by the C-Type Natriuretic Peptide. Rintz E(1)(2), Węgrzyn G(1), Fujii T(3), Tomatsu S(2)(4). Author information: (1)Department of Molecular Biology, Faculty of Biology, University of Gdansk, 80-308 Gdansk, Poland. (2)Skeletal Dysplasia Res...

Expression of Sulf1 and Sulf2 in cartilage, bone and endochondral fracture healing.

Histochemistry and cell biology | 2016 | Zaman G, Staines KA, Farquharson C, Newton PT

[Indexed for MEDLINE]

Epiphyseal Growth Plate Fracture-Separations

Pediatric Orthopedic Deformities, Volume 1 | 2016 | Frederic Shapiro

Role of c-Myb in chondrogenesis.

Bone | 2015 | Oralová V, Matalová E, Janečková E, Drobná Krejčí E

[Indexed for MEDLINE] 18. Dev Dyn. 2022 Jan;251(1):75-94. doi: 10.1002/dvdy.438. Epub 2021 Nov 27. Cross-talk between EGFR and BMP signals regulates chondrocyte maturation during endochondral ossification. Lees-Shepard JB(1), Flint K(2), Fisher M(2), Omi M(1), Richard K(1), Antony M(2), Chen PJ(2), Yadav S(2), Threadgill D(3)(4), Maihle NJ(5)(6), Dealy CN(2)(7)(8)(9). Author in...

Genetic regulation of the growth plate.

Frontiers in endocrinology | 2011 | Karimian E, Chagin AS, Sävendahl L

14. Growth Horm IGF Res. 2026 Mar;83:101679. doi: 10.1016/j.ghir.2026.101679. Epub 2026 Jan 7. The growth plate: Zonal architecture, plasticity, and endocrine control of linear growth. Ostria CB(1), Yakar S(2). Author information: (1)Escuela de Medicina, Colegio de Ciencias de la Salud, Universidad San Francisco de Quito, Quito, 170901, Ecuador. (2)Department of Molecular Patho...

Fibroblast growth factor expression in the postnatal growth plate.

Bone | 2007 | Lazarus JE, Hegde A, Andrade AC, Nilsson O

[Indexed for MEDLINE] 20. Histochem Cell Biol. 2016 Jan;145(1):67-79. doi: 10.1007/s00418-015-1365-8. Epub 2015 Oct 14. Expression of Sulf1 and Sulf2 in cartilage, bone and endochondral fracture healing. Zaman G(1), Staines KA(2), Farquharson C(2), Newton PT(2), Dudhia J(3), Chenu C(1), Pitsillides AA(1), Dhoot GK(4). Author information: (1)Department of Comparative Biomedical...

Epiphyseal Growth Plate Fractures

Journal unavailable | 2007

Epiphyseal Growth Plate Fracture–Separations

Pediatric Orthopedic Deformities | 2001 | FREDERIC SHAPIRO

Metacarpal

Epiphyseal Growth Plate Fractures

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Epiphyseal Growth Plate Fractures

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Epiphyseal Growth Plate Fractures