Orthonotes
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Evidence Search

Search reputable indexed orthopaedic literature from multiple scholarly sources, classify the evidence, and link papers directly to wiki topics and cases.

Sources: PubMed, Europe PMC, Crossref

Linking results to Wiki: CRPS — Budapest Criteria
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Results are classified automatically from source metadata across PubMed, Europe PMC, and Crossref.
PubMed Crossref
PubMed Guideline / Consensus Evidence High

Diagnostic Guidance for Chronic Complex Regional Pain Syndrome Type I and Type II from The American Society of Interventional Physicians (ASIPP).

Pain physician | 2025 | Gharibo C, Day M, Aydin SM, Kaye AD

[Indexed for MEDLINE] 4. Kathmandu Univ Med J (KUMJ). 2024 Jan-Mar;22(85):123-126. Complex Regional Pain Syndrome. Shakya S (1), Amatya S (2), Thapa S (2), Thapa P (3), Pokharel S (4). Author information: (1)Department of Anesthesiology and Critical Care, Dhulikhel Hospital, Kathmandu University Hospital, Kathmandu University School of Medical Sciences, Dhulikhel, Kavre, Nepal....

PubMed Systematic Review / Meta-analysis Evidence High

Management of complex regional pain syndrome in trauma and orthopaedic surgery-a systematic review.

British medical bulletin | 2023 | Saed A, Neal-Smith G, Fernquest S, Bourget-Murray J

[Indexed for MEDLINE] 9. Pain. 2015 Apr;156 Suppl 1:S94-S103. doi: 10.1097/01.j.pain.0000460344.54470.20. Complex regional pain syndrome-significant progress in understanding. Birklein F(1), Schlereth T. Author information: (1)Department of Neurology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany. Research into complex regional pain syndro...

PubMed Narrative Review Evidence Moderate

The Warm Phase of CRPS Type-1: Is It Time to Review the Budapest Criteria?

Diagnostics (Basel, Switzerland) | 2025 | Saviola G, Rosini S, Molfetta L, Dalle Carbonare L

Conflict of interest statement: The authors declare no conflicts of interest. 7. FP Essent. 2023 Oct;533:21-26. Chronic Pain Syndromes: Complex Regional Pain Syndrome. Grinshpun G(1). Author information: (1)Interdisciplinary Pain Management Center - Madigan Army Medical Center, Joint Base Lewis-McChord, WA. Complex regional pain syndrome (CRPS) is a chronic pain condition chara...

PubMed Narrative Review Evidence Moderate

Complex Regional Pain Syndrome: Diagnosis, Pathophysiology, and Treatment Approaches.

Cureus | 2024 | Lima Pessôa B, Netto JGM, Adolphsson L, Longo L

Conflict of interest statement: Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at presen...

PubMed Narrative Review Evidence Moderate

Interventional pain management of CRPS in the pediatric population: A literature review.

Interventional pain medicine | 2024 | Mosquera-Moscoso J, Eldrige J, Encalada S, Mendonca LFP

Conflict of interest statement: The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Christine Hunt reports a relationship with 10.13039/100019969Nevro Corp that includes: funding grants, not related to this study. If there are other authors, they declare that they have no known competing financia...

PubMed Narrative Review Evidence Moderate

Utility of Radionuclide Bone Scintigraphy in Complex Regional Pain Syndrome.

Current pain and headache reports | 2018 | Howard BA, Roy L, Kaye AD, Pyati S

[Indexed for MEDLINE] 11. Sci Rep. 2025 Jul 16;15(1):25745. doi: 10.1038/s41598-025-11356-5. Evaluation of the efficacy and tolerance of pamidronate in complex regional pain syndrom type 1. Doussiere M(1), Besnier C(2), Hamidou Y(2), Jesson C(2), Danial JS(2), Jarde O(3), Fardellone P(2), Goëb V(2). Author information: (1)Department of Rheumatology, University of Picardie Jules...

PubMed Narrative Review Evidence Moderate

Complex regional pain syndrome type I in children: What is new?

Orthopaedics & traumatology, surgery & research : OTSR | 2017 | Lascombes P, Mamie C

[Indexed for MEDLINE] 14. J Oral Sci. 2020 Sep 26;62(4):455-457. doi: 10.2334/josnusd.19-0437. Epub 2020 Sep 9. Orofacial complex regional pain syndrome. Kalladka M(1), Alhasan H(1), Morubagal N(2), Noma N(3), Khan J(1). Author information: (1)Orofacial Pain and Temporomandibular Disorders, Eastman Institute for Oral Health. (2)Division of Anaesthetics and Pain, University Hosp...

PubMed Narrative Review Evidence Moderate

[COMPLEX REGIONAL PAIN SYNDROME].

Lijecnicki vjesnik | 2015 | Blažeković I, Bilić E, Žagar M, Anić B

[Indexed for MEDLINE] 6. Diagnostics (Basel). 2025 Sep 20;15(18):2397. doi: 10.3390/diagnostics15182397. The Warm Phase of CRPS Type-1: Is It Time to Review the Budapest Criteria? Saviola G(1), Rosini S(2), Molfetta L(3), Dalle Carbonare L(4), Malavolta N(5), Di Meglio N(6), Mazzei MA(6), Muratore M(7), Frediani B(8); G.E.O.D.E.I.T (“Bone Marrow Edema Diagnosis and Therapeutic...

PubMed Narrative Review Evidence Moderate

Complex regional pain syndrome-significant progress in understanding.

Pain | 2015 | Birklein F, Schlereth T

[Indexed for MEDLINE] 10. Curr Pain Headache Rep. 2018 Feb 1;22(1):7. doi: 10.1007/s11916-018-0659-7. Utility of Radionuclide Bone Scintigraphy in Complex Regional Pain Syndrome. Howard BA(1), Roy L(2), Kaye AD(3), Pyati S(4)(5). Author information: (1)Division of Nuclear Medicine, Department of Radiology, Duke University Medical Center, Durham, NC, 27710, USA. (2)Department of...

PubMed Narrative Review Evidence Moderate

Complex regional pain syndrome (CRPS) type I: historical perspective and critical issues.

Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases | 2015 | Iolascon G, de Sire A, Moretti A, Gimigliano F

17. Eur J Pain. 2019 Nov;23(10):1890-1903. doi: 10.1002/ejp.1463. Epub 2019 Aug 22. Complex regional pain syndrome: An international survey of clinical practice. Grieve S(1)(2), Llewellyn A(1)(2), Jones L(2), Manns S(2), Glanville V(3), McCabe CS(1)(2)(4). Author information: (1)CRPS Service, Royal United Hospitals Bath NHS Foundation Trust, Bath, UK. (2)Faculty of Health and A...

PubMed Case Report / Series Evidence Low

Complex Regional Pain Syndrome.

Kathmandu University medical journal (KUMJ) | 2024 | Shakya S , Amatya S , Thapa S , Thapa P

[Indexed for MEDLINE] 5. Lijec Vjesn. 2015 Sep-Oct;137(9-10):297-306. [COMPLEX REGIONAL PAIN SYNDROME]. [Article in Croatian] Blažeković I, Bilić E, Žagar M, Anić B. Complex regional pain syndrome (CRPS) represents a state of constant and often disabling pain, affecting one region (usually hand) and often occurs after a trauma whose severity does not correlate with the level of...

PubMed Original Article Evidence Unclassified

Complex Regional Pain Syndrome.

Journal unavailable | 2026 | Guthmiller KB, Dua A, Dey S, Varacallo MA

Conflict of interest statement: Disclosure: Kevin Guthmiller declares no relevant financial relationships with ineligible companies. Disclosure: Anterpreet Dua declares no relevant financial relationships with ineligible companies. Disclosure: Saugat Dey declares no relevant financial relationships with ineligible companies. Disclosure: Matthew Varacallo declares no relevant fi...

PubMed Original Article Evidence Unclassified

Evaluation of the efficacy and tolerance of pamidronate in complex regional pain syndrom type 1.

Scientific reports | 2025 | Doussiere M, Besnier C, Hamidou Y, Jesson C

[Indexed for MEDLINE] Conflict of interest statement: Declarations. Conflict of interest: The authors declare no conflicts of interest. No specific funding was received from any bodies in the public, commercial or not-for-profit sectors to carry out the work described in this article. 12. Interv Pain Med. 2024 Dec 2;3(4):100532. doi: 10.1016/j.inpm.2024.100532. eCollection 2024...

PubMed Case Report / Series Evidence Low

Orofacial complex regional pain syndrome.

Journal of oral science | 2020 | Kalladka M, Alhasan H, Morubagal N, Noma N

[Indexed for MEDLINE] 15. Arthrosc Sports Med Rehabil. 2021 May 15;3(4):e1037-e1045. doi: 10.1016/j.asmr.2021.03.009. eCollection 2021 Aug. Complex Region Pain Syndrome Following Shoulder Surgery. Magone KM(1), Ben-Ari E(1), Hacquebord JH(2), Virk MS(1). Author information: (1)Divisions of Shoulder and Elbow Surgery, Department of Orthopedic Surgery, NYU Grossman School of Medi...

PubMed Original Article Evidence Unclassified

Chronic Pain Syndromes: Complex Regional Pain Syndrome.

FP essentials | 2023 | Grinshpun G

[Indexed for MEDLINE] 8. Br Med Bull. 2023 Jun 21;146(1):27-42. doi: 10.1093/bmb/ldac034. Management of complex regional pain syndrome in trauma and orthopaedic surgery-a systematic review. Saed A(1), Neal-Smith G(1), Fernquest S(1), Bourget-Murray J(1), Wood A(1). Author information: (1)Investigation Performed at the Trauma & Orthopaedic Department, Oxford Trauma Unit, John Ra...

PubMed Original Article Evidence Unclassified

Treatment of Distal Radius Fracture: Does Early Activity Postinjury Lead to a Lower Incidence of Complex Regional Pain Syndrome?

Hand (New York, N.Y.) | 2022 | Boersma EZ, Meent HV, Klomp FP, Frölke JM

[Indexed for MEDLINE] Conflict of interest statement: Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. 19. Unfallchirurg. 2018 Oct;121(10):825-838. doi: 10.1007/s00113-018-0544-1. [Complex regional pain syndrome]. [Article in German] Herlyn P(1). Author i...

PubMed Original Article Evidence Unclassified

Complex Region Pain Syndrome Following Shoulder Surgery.

Arthroscopy, sports medicine, and rehabilitation | 2021 | Magone KM, Ben-Ari E, Hacquebord JH, Virk MS

16. Clin Cases Miner Bone Metab. 2015 Jan-Apr;12(Suppl 1):4-10. doi: 10.11138/ccmbm/2015.12.3s.004. Epub 2016 Apr 7. Complex regional pain syndrome (CRPS) type I: historical perspective and critical issues. Iolascon G(1), de Sire A(1), Moretti A(1), Gimigliano F(2). Author information: (1)Department of Medical and Surgical Specialties and Dentistry, Second University of Naples,...

PubMed Original Article Evidence Unclassified

Complex regional pain syndrome: An international survey of clinical practice.

European journal of pain (London, England) | 2019 | Grieve S, Llewellyn A, Jones L, Manns S

[Indexed for MEDLINE] 18. Hand (N Y). 2022 Jan;17(1):119-127. doi: 10.1177/1558944719895782. Epub 2020 Jan 9. Treatment of Distal Radius Fracture: Does Early Activity Postinjury Lead to a Lower Incidence of Complex Regional Pain Syndrome? Boersma EZ(1), Meent HV(1), Klomp FP(1), Frölke JM(1), Nijhuis-van der Sanden MWG(1), Edwards MJR(1). Author information: (1)Radboud Universi...

PubMed Original Article Evidence Unclassified

[Complex regional pain syndrome].

Der Unfallchirurg | 2018 | Herlyn P

[Indexed for MEDLINE] 20. Eur J Radiol. 2020 Aug;129:109044. doi: 10.1016/j.ejrad.2020.109044. Epub 2020 May 6. MRI of complex regional pain syndrome in the foot. Agten CA(1), Kobe A(2), Barnaure I(3), Galley J(3), Pfirrmann CW(3), Brunner F(4). Author information: (1)University Hospital Balgrist, Radiology, Forchstrasse 340, 8008 Zurich, Switzerland; University of Zurich, Facu...

Crossref Scholarly Work Evidence Unclassified

Diagnostic Accuracy of Hand Surgeons and Pain Specialists in Diagnosing CRPS Based on the Budapest Criteria

Journal unavailable | Pattariya Jänsch, Ariane Asmus, Sofia Pappa-Eisenschenk, Andreas Eisenschenk

Abstract BackgroundThe clinical presentation of complex regional pain syndrome is heterogenous. The Budapest criteria give a list of symptoms and signs for the diagnosis. But the physician will often set the diagnosis clinically from the collection of symptoms and his or her experience. This study examines the accuracy of hand surgeons and pain specialists for diagnosing CRPS u...