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Evidence Search

Search reputable indexed orthopaedic literature from multiple scholarly sources, classify the evidence, and link papers directly to wiki topics and cases.

Sources: PubMed, Europe PMC, Crossref

Linking results to Wiki: Tendon Healing and Rehabilitation
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Results are classified automatically from source metadata across PubMed, Europe PMC, and Crossref.
PubMed Crossref
PubMed Systematic Review / Meta-analysis Evidence High

Guidelines on offloading foot ulcers in persons with diabetes (IWGDF 2023 update).

Diabetes/metabolism research and reviews | 2024 | Bus SA, Armstrong DG, Crews RT, Gooday C

[Indexed for MEDLINE] 8. Int J Mol Sci. 2025 Nov 6;26(21):10804. doi: 10.3390/ijms262110804. Platelet-Rich Plasma (PRP): Molecular Mechanisms, Actions and Clinical Applications in Human Body. Wu WS(1), Chen LR(2)(3), Chen KH(4)(5). Author information: (1)Department of Medical Education, Taipei Tzu-Chi Hospital, The Buddhist Tzu-Chi Medical Foundation, New Taipei City 231, Taiwa...

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PubMed Randomized Controlled Trial Evidence High

Progressive early passive and active exercise therapy after surgical rotator cuff repair - study protocol for a randomized controlled trial (the CUT-N-MOVE trial).

Trials | 2018 | Kjær BH, Magnusson SP, Warming S, Henriksen M

[Indexed for MEDLINE] Conflict of interest statement: ETHICS APPROVAL AND CONSENT TO PARTICIPATE: The Health Research Study Board for the Capital Region Denmark approved the study on the 18 October 2016 (H-16033995). The study will be conducted in accordance with the local research ethics committee requirements and the principles of the Declaration of Helsinki, thus informed co...

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PubMed Randomized Controlled Trial Evidence High

The Ruptured Achilles Tendon Elongates for 6 Months After Surgical Repair Regardless of Early or Late Weightbearing in Combination With Ankle Mobilization: A Randomized Clinical Trial.

The American journal of sports medicine | 2018 | Eliasson P, Agergaard AS, Couppé C, Svensson R

[Indexed for MEDLINE] 14. Sci Transl Med. 2025 Dec 10;17(828):eado6948. doi: 10.1126/scitranslmed.ado6948. Epub 2025 Dec 10. A bioinspired mineralized collagen scaffold promotes enthesis healing and activates Gli1 expression in preclinical models. Zhang T(1)(2), Lei T(1)(2), Han J(1)(2), Chen Y(3), Nie Y(2)(4)(5), Zhang R(1)(2)(5), Cai H(1)(2), Guo Z(2)(4)(5), Yan R(1)(2)(5), L...

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PubMed Narrative Review Evidence Moderate

Platelet-Rich Plasma (PRP): Molecular Mechanisms, Actions and Clinical Applications in Human Body.

International journal of molecular sciences | 2025 | Wu WS, Chen LR, Chen KH

[Indexed for MEDLINE] Conflict of interest statement: The authors declare no conflicts of interest. 9. Trials. 2018 Sep 3;19(1):470. doi: 10.1186/s13063-018-2839-5. Progressive early passive and active exercise therapy after surgical rotator cuff repair - study protocol for a randomized controlled trial (the CUT-N-MOVE trial). Kjær BH(1)(2), Magnusson SP(3)(4), Warming S(3), He...

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PubMed Narrative Review Evidence Moderate

Challenges in tendon-bone healing: emphasizing inflammatory modulation mechanisms and treatment.

Frontiers in endocrinology | 2024 | Jiang F, Zhao H, Zhang P, Bi Y

[Indexed for MEDLINE] Conflict of interest statement: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. 17. J Orthop Surg Res. 2024 Dec 3;19(1):817. doi: 10.1186/s13018-024-05304-8. Mechanisms of tendon-bone interface healing: biomechanics, cell mechanics,...

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PubMed Narrative Review Evidence Moderate

Mechanisms of tendon-bone interface healing: biomechanics, cell mechanics, and tissue engineering approaches.

Journal of orthopaedic surgery and research | 2024 | Xu Z, Xu W, Zhang T, Luo L

[Indexed for MEDLINE] Conflict of interest statement: Declarations. Ethical approval: Not applicable. Informed consent: Not applicable. Competing interests: The authors declare no competing interests. 18. Orthop Traumatol Surg Res. 2019 Feb;105(1S):S63-S73. doi: 10.1016/j.otsr.2018.06.012. Epub 2018 Aug 18. Failed rotator cuff repair. Desmoineaux P(1). Author information: (1)Ce...

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PubMed Narrative Review Evidence Moderate

Extracorporeal Shockwave Therapy in the Management of Sports Medicine Injuries.

Current sports medicine reports | 2021 | Schroeder AN, Tenforde AS, Jelsing EJ

[Indexed for MEDLINE] 3. Int Orthop. 2020 May;44(5):893-903. doi: 10.1007/s00264-020-04511-2. Epub 2020 Mar 10. Physical therapy and precision rehabilitation in shoulder rotator cuff disease. Longo UG(1), Risi Ambrogioni L(2), Berton A(2), Candela V(2), Carnevale A(2)(3), Schena E(3), Gugliemelli E(4), Denaro V(2). Author information: (1)Department of Orthopaedic and Trauma Sur...

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PubMed Narrative Review Evidence Moderate

Physical therapy and precision rehabilitation in shoulder rotator cuff disease.

International orthopaedics | 2020 | Longo UG, Risi Ambrogioni L, Berton A, Candela V

[Indexed for MEDLINE] 4. Br J Sports Med. 2009 Apr;43(4):247-52. doi: 10.1136/bjsm.2008.054239. Epub 2009 Feb 24. Mechanotherapy: how physical therapists' prescription of exercise promotes tissue repair. Khan KM(1), Scott A. Author information: (1)Centre for Hip Health and Mobility and Department of Family Practice, University of British Columbia, Vancouver, Canada. karim.khan@...

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PubMed Narrative Review Evidence Moderate

Achilles tendinopathy.

Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons | 2020 | Maffulli N, Longo UG, Kadakia A, Spiezia F

[Indexed for MEDLINE] 6. Am Fam Physician. 2011 Jan 1;83(1):39-46. Stress fractures: diagnosis, treatment, and prevention. Patel DS(1), Roth M, Kapil N. Author information: (1)Rush-Copley Family Medicine Residency, Aurora, Illinois 60504, USA. Deepak_S_Patel@rsh.net Stress fractures are common injuries in athletes and military recruits. These injuries occur more commonly in low...

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PubMed Narrative Review Evidence Moderate

Failed rotator cuff repair.

Orthopaedics & traumatology, surgery & research : OTSR | 2019 | Desmoineaux P

[Indexed for MEDLINE] 19. Hand Clin. 2015 Nov;31(4):641-50. doi: 10.1016/j.hcl.2015.06.010. Distal Triceps Tendon Injuries. Keener JD(1), Sethi PM(2). Author information: (1)Department of Orthopaedic Surgery, Washington University, CB# 8233, 660 South Euclid Avenue, St Louis, MO 63110, USA. Electronic address: keenerj@wustl.edu. (2)The ONS Sports and Shoulder Service, 6 Greenwi...

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PubMed Narrative Review Evidence Moderate

Flexor Tendon Injuries.

The Journal of the American Academy of Orthopaedic Surgeons | 2018 | Klifto CS, Capo JT, Sapienza A, Yang SS

[Indexed for MEDLINE] 11. Joint Bone Spine. 2007 Dec;74(6):551-7. doi: 10.1016/j.jbspin.2007.08.003. Epub 2007 Oct 12. Rotator cuff repair. Favard L(1), Bacle G, Berhouet J. Author information: (1)Orthopedic Surgery and Trauma Department, Trousseau Teaching Hospital, Tours, France. favard@med.univ-tours.fr Rotator cuff surgery is developing at a fast pace, with progress in arth...

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PubMed Narrative Review Evidence Moderate

Rotator cuff rehabilitation: current theories and practice.

The Physician and sportsmedicine | 2016 | Osborne JD, Gowda AL, Wiater B, Wiater JM

[Indexed for MEDLINE] 2. Curr Sports Med Rep. 2021 Jun 1;20(6):298-305. doi: 10.1249/JSR.0000000000000851. Extracorporeal Shockwave Therapy in the Management of Sports Medicine Injuries. Schroeder AN(1), Tenforde AS(2), Jelsing EJ(3). Author information: (1)Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN. (2)Physical Medicine and Rehabilitation, Spaulding Rehab...

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PubMed Narrative Review Evidence Moderate

Distal Triceps Tendon Injuries.

Hand clinics | 2015 | Keener JD, Sethi PM

[Indexed for MEDLINE] 20. J Orthop Res. 2025 Apr;43(4):746-755. doi: 10.1002/jor.26044. Epub 2025 Jan 12. Muscle Contraction Is Essential for Tendon Healing and Muscle Function Recovery After Achilles Tendon Rupture and Surgical Repair. Yoneno M(1)(2), Minegishi Y(3), Takahashi H(1)(2), Takahata K(1)(2), Miyamoto H(1), Usami Y(1), Kokubun T(1)(4). Author information: (1)Graduat...

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PubMed Narrative Review Evidence Moderate

Stress fractures: diagnosis, treatment, and prevention.

American family physician | 2011 | Patel DS, Roth M, Kapil N

[Indexed for MEDLINE] 7. Diabetes Metab Res Rev. 2024 Mar;40(3):e3647. doi: 10.1002/dmrr.3647. Epub 2023 May 25. Guidelines on offloading foot ulcers in persons with diabetes (IWGDF 2023 update). Bus SA(1)(2), Armstrong DG(3), Crews RT(4), Gooday C(5), Jarl G(6)(7), Kirketerp-Moller K(8)(9), Viswanathan V(10), Lazzarini PA(11)(12). Author information: (1)Department of Rehabilit...

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PubMed Original Article Evidence Unclassified

A bioinspired mineralized collagen scaffold promotes enthesis healing and activates Gli1 expression in preclinical models.

Science translational medicine | 2025 | Zhang T, Lei T, Han J, Chen Y

[Indexed for MEDLINE] 15. Oper Orthop Traumatol. 2016 Jun;28(3):177-92. doi: 10.1007/s00064-016-0438-8. Epub 2016 Feb 19. [Subtalar arthrodesis]. [Article in German] Fuhrmann RA(1), Pillukat T(2). Author information: (1)Klinik für Fuß- und Sprunggelenkchirurgie, Rhön-Klinikum, Salzburger Leite 1, 97616, Bad Neustadt, Deutschland. ReneeAndrea.Fuhrmann@fusschirurgie-bad-neustadt....

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PubMed Narrative Review Evidence Moderate

Mechanotherapy: how physical therapists' prescription of exercise promotes tissue repair.

British journal of sports medicine | 2009 | Khan KM, Scott A

[Indexed for MEDLINE] Conflict of interest statement: Competing interests: None. 5. Foot Ankle Surg. 2020 Apr;26(3):240-249. doi: 10.1016/j.fas.2019.03.009. Epub 2019 Apr 18. Achilles tendinopathy. Maffulli N(1), Longo UG(2), Kadakia A(3), Spiezia F(4). Author information: (1)Department of Musculoskeletal Disorders, University of Salerno School of Medicine, Surgery and Dentistr...

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PubMed Narrative Review Evidence Moderate

ACL fixation devices.

Sports medicine and arthroscopy review | 2009 | Hapa O, Barber FA

[Indexed for MEDLINE] 13. Am J Sports Med. 2018 Aug;46(10):2492-2502. doi: 10.1177/0363546518781826. Epub 2018 Jul 2. The Ruptured Achilles Tendon Elongates for 6 Months After Surgical Repair Regardless of Early or Late Weightbearing in Combination With Ankle Mobilization: A Randomized Clinical Trial. Eliasson P(1)(2), Agergaard AS(1)(3), Couppé C(1)(3), Svensson R(1), Hoeffner...

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PubMed Narrative Review Evidence Moderate

Rotator cuff repair.

Joint bone spine | 2007 | Favard L, Bacle G, Berhouet J

[Indexed for MEDLINE] 12. Sports Med Arthrosc Rev. 2009 Dec;17(4):217-23. doi: 10.1097/JSA.0b013e3181bf668c. ACL fixation devices. Hapa O(1), Barber FA. Author information: (1)Plano Orthopedic Sports Medicine and Spine Center, Plano, TX, USA. Secure graft fixation for anterior cruciate ligament reconstruction is an important goal. Optimally, graft fixation allows for an aggress...

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Crossref Journal Article Evidence Unclassified

MRL/MpJ tendon matrix‐derived therapeutic promotes improved healing outcomes in scar‐mediated canonical tendon healing

Journal of Orthopaedic Research | 2021 | Juan Paredes, Ashley Pekmezian, Nelly Andarawis‐Puri

AbstractTendons are commonly injured connective soft tissues characterized by an ineffective healing response that results in scar formation and loss of functional and structural properties. Naturally occurring extracellular matrix (ECM) constructs have become a promising therapeutic for tendon injuries due to their capacity to harness a complex biological environment. However,...

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PubMed Original Article Evidence Unclassified

[Subtalar arthrodesis].

Operative Orthopadie und Traumatologie | 2016 | Fuhrmann RA, Pillukat T

[Indexed for MEDLINE] 16. Front Endocrinol (Lausanne). 2024 Nov 6;15:1485876. doi: 10.3389/fendo.2024.1485876. eCollection 2024. Challenges in tendon-bone healing: emphasizing inflammatory modulation mechanisms and treatment. Jiang F(1), Zhao H(1), Zhang P(1), Bi Y(1), Zhang H(1), Sun S(2), Yao Y(1), Zhu X(2), Yang F(1), Liu Y(1), Xu S(1), Yu T(2), Xiao X(3). Author information...

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Crossref Journal Article Evidence Unclassified

Is cultured tendon fibroblast a good model to study tendon healing?

Journal of Orthopaedic Research | 2008 | Sai‐Chuen Fu, Yau‐Chuk Cheuk, Kai‐Ming Chan, Leung‐Kim Hung

AbstractCultured tendon fibroblasts (CTFs) from intact explants are widely used to study tendon healing in vitro. The significance of these findings may rely on similarities between CTFs and healing tendon fibroblasts in situ. Our purpose was to compare CTFs with fibroblasts cultured from healing tendons. We cultured CTFs from intact and healing tendons at day 7 and day 14 post...

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