The biopsy.

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Abstract

[Indexed for MEDLINE] 15. Eur J Orthop Surg Traumatol. 2015 Jan;25(1):5-15. doi: 10.1007/s00590-014-1468-2. Epub 2014 May 3. State-of-the-art approach for bone sarcomas. Mavrogenis AF(1), Angelini A, Vottis C, Palmerini E, Rimondi E, Rossi G, Papagelopoulos PJ, Ruggieri P. Author information: (1)First Department of Orthopaedics, ATTIKON University Hospital, Athens University Medical School, 41 Ventouri Street, Holargos, 15562, Athens, Greece, afm@otenet.gr. Bone sarcomas are a variety of non-epithelial, malignant neoplasms of bone. The most common bone sarcomas are osteosarcoma, Ewing's sarcoma, and chondrosarcoma. The approach to a patient with a suspected bone sarcoma from initial examination to the histological diagnosis and classification is staging. Staging is of critical importance, in order to classify different treatment options and point out which combination of them is more suitable depending on the severity of the tumor in every individual patient. Staging should include medical history, physical and imaging examination, and biopsy. This article presents the current approach for staging, principles of biopsy, tumor classification, treatment, and follow-up of patients with bone sarcomas. DOI: 10.1007/s00590-014-1468-2