The imaging of myositis ossificans.

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Abstract

[Indexed for MEDLINE] 11. Surg Pathol Clin. 2015 Sep;8(3):419-44. doi: 10.1016/j.path.2015.05.004. Chondro-Osseous Lesions of Soft Tissue. Cho SJ(1), Horvai A(2). Author information: (1)Pathology, UCSF Medical Center Mission Bay, 1825 4th Street, Room M2354, San Francisco, CA 94158, USA. (2)Pathology, UCSF Medical Center Mission Bay, 1825 4th Street, Room M2354, San Francisco, CA 94158, USA. Electronic address: andrew.horvai@ucsf.edu. Soft tissue lesions can contain bone or cartilage matrix as an incidental, often metaplastic, phenomenon or as a diagnostic feature. The latter category includes a diverse group ranging from self-limited proliferations to benign neoplasms to aggressive malignancies. Correlating imaging findings with pathology is mandatory to confirm that a tumor producing bone or cartilage, in fact, originates from soft tissue rather than from the skeleton. The distinction can have dramatic diagnostic and therapeutic implications. This content focuses on the gross, histologic, radiographic, and clinical features of bone or cartilage-producing soft tissue lesions. Recent discoveries regarding tumor-specific genetics are discussed. Copyright © 2015 Elsevier Inc. All rights reserved. DOI: 10.1016/j.path.2015.05.004