Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association | 2024 | Yamanaka T, Matsumura T, Ae R, Takeshita K
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[Indexed for MEDLINE] Conflict of interest statement: Declaration of competing interest The authors declare that they have no conflict of interest. 6. Sci Rep. 2023 Jul 26;13(1):12090. doi: 10.1038/s41598-023-38667-9. Influencing factors on morbidity and mortality in intertrochanteric fractures. Babagoli M(1), Ghaseminejad Raeini A(2), Sheykhvatan M(2), Baghdadi S(3), Shafiei SH(2). Author information: (1)Sina University Hospital, Tehran University of Medical Sciences, Tehran, Iran. m.babagoli77@gmail.com. (2)Orthopedic Surgery Research Center, Sina University Hospital, Tehran University of Medical Sciences, Tehran, Iran. (3)Pediatric Orthopaedic Surgery Department, Montefiore Medical Center, New York, USA. We aimed to evaluate the effect of the patient's clinical and paraclinical condition before and after surgery on short-term mortality and complication and long-term mortality. A retrospective cohort study was conducted and multivariate logistic regression was applied to determine the effect of demographic characteristics (sex, age, AO/OTA classification, height, weight, body mass index), medical history (hypertension, ischemic heart disease, diabetes mellitus, thyroid malfunction, cancer, osteoporosis, smoking) lab data (Complete blood cell, blood sugar, Blood Urea Nitrogen, Creatinine, Na, and K), surgery-related factors (Anesthesia time and type, implant, intraoperative blood transfusion, postoperative blood transfusion, and operation time), duration of admission to surgery and anticoagulant consumption on short-term mortality and complication and long-term mortality. Three hundred ten patients from November 2016 to September 2020 were diagnosed with an intertrochanteric fracture. 3.23% of patients died in hospital, 14.1% of patients confronted in-hospital complications, and 38.3% died after discharge till the study endpoint. ΔNumber of Neutrophiles is the primary determinant for in-hospital mortality in multivariate analysis. Age and blood transfusion are the main determinants of long-term mortality, and Na before surgery is the primary variable associated with postoperative complications. Among different analytical factors Na before surgery as a biomarker presenting dehydration was the main prognostic factor for in hospital complications. In hospital mortality was mainly because of infection and long-term mortality was associated with blood transfusion. © 2023. The Author(s). DOI: 10.1038/s41598-023-38667-9 PMCID: PMC10372085
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