X-Linked Hypophosphataemia and Burosumab: A Systemic Disease With a New Treatment.

Journal and index pages often block iframe embedding. This reader keeps the evidence details in Orthonotes and leaves the source page one click away.

Abstract

[Indexed for MEDLINE] Conflict of interest statement: J.L.S., C.F.M., A.S., P.S., C.R., and A.B. have participated in research funded by Kyowa Kirin. A.S., P.S., C.F.M. have received honoraria by Kyowa Kirin for educational presentations. C.F.M. has received consulting fees from Kyowa Kirin. 14. Orthop Clin North Am. 2019 Apr;50(2):181-191. doi: 10.1016/j.ocl.2018.10.002. The Role of Vitamin D in Pediatric Orthopedics. Horan MP(1), Williams K(2), Hughes D(2). Author information: (1)Pediatric Orthopaedic Surgery, Palmetto Health-USC Orthopaedic Center, University of South Carolina, 14 Medical Park, Suite 200, Columbia, SC 29203, USA. Electronic address: michael.horan@palmettohealth.org. (2)Department of Orthopaedic Surgery, University of South Carolina School of Medicine, Medical Park 2, Suite 400, Columbia, SC 29203, USA. Understanding the role of vitamin D is an important component of the proper care of the pediatric orthopedic patient. Vitamin D is an essential component of bone metabolism in the growth and development of the pediatric skeleton, which can be acutely affected by changes to the body's vitamin D, calcium, and phosphate levels, resulting in pathologic conditions such as rickets or fractures. This article reviews the main areas in which vitamin D relates to pediatric orthopedics and highlights some of the areas where future research is being directed. Copyright © 2018 Elsevier Inc. All rights reserved. DOI: 10.1016/j.ocl.2018.10.002