Interprosthetic femoral fractures: management challenges.

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Abstract

Conflict of interest statement: Dr Ran Schwarzkopf provided consultancy service to Smith & Nephew, holds stock options from Intelijoint, and involved in the Gauss Surgical Research for Smith & Nephew. The authors report no other conflicts of interest in this work. 12. Curr Osteoporos Rep. 2025 Jun 23;23(1):29. doi: 10.1007/s11914-025-00922-5. The Role of Osteoporosis in Total Hip Arthroplasty Periprosthetic Fractures and Current Management Strategies: a Review. Bauer J(1), Duero J(2), Lindsay A(3). Author information: (1)Department of Orthopaedic Surgery, University of Connecticut, 120 Dowling Way, Farmington, CT, 06030, USA. jbauer@uchc.edu. (2)University of Connecticut School of Medicine, 200 Academic Way, Farmington, CT, 06032, USA. (3)Department of Orthopaedic Surgery, University of Connecticut, 120 Dowling Way, Farmington, CT, 06030, USA. PURPOSE OF REVIEW: This review provides a background on osteoporosis, describes the relationship between osteoporosis and periprosthetic fracture following total hip arthroplasty (THA), as well as to discusses current management strategies and future directions for improved patient outcomes. RECENT FINDINGS: Periprosthetic fracture of the hip is among one of the most common reasons for revision following THA and occurs in 0.1-3.5% of individuals. Periprosthetic fractures come with significant cost, morbidity, and future mortality. Risks for periprosthetic fractures following THA include female sex, older age, rheumatoid arthritis, and osteoporosis. Recent works have demonstrated that osteoporosis plays an important role in the rising prevalence of periprosthetic fractures following THA. This review characterizes the interplay between osteoporosis and periprosthetic hip fractures following THA with emphasis placed upon the pathophysiology of osteoporosis, the mechanisms by which osteoporosis promote periprosthetic fractures, management of such fractures, and the potential for future therapies. © 2025. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature. DOI: 10.1007/s11914-025-00922-5