Bone cysts: unicameral and aneurysmal bone cyst.

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Abstract

[Indexed for MEDLINE] 2. J Am Acad Orthop Surg. 2012 Apr;20(4):233-41. doi: 10.5435/JAAOS-20-04-233. Aneurysmal bone cyst. Rapp TB(1), Ward JP, Alaia MJ. Author information: (1)Department of Orthopaedic Surgery, NYU Hospital for Joint Diseases, New York, NY, USA. Aneurysmal bone cysts are rare skeletal tumors that most commonly occur in the first two decades of life. They primarily develop about the knee but may arise in any portion of the axial or appendicular skeleton. Pathogenesis of these tumors remains controversial and may be vascular, traumatic, or genetic. Radiographic features include a dilated, radiolucent lesion typically located within the metaphyseal portion of the bone, with fluid-fluid levels visible on MRI. Histologic features include blood-filled lakes interposed between fibrous stromata. Differential diagnosis includes conditions such as telangiectatic osteosarcoma and giant cell tumor. The mainstay of treatment is curettage and bone graft, with or without adjuvant treatment. Other management options include cryotherapy, sclerotherapy, radionuclide ablation, and en bloc resection. The recurrence rate is low after appropriate treatment; however, more than one procedure may be required to completely eradicate the lesion. DOI: 10.5435/JAAOS-20-04-233