Solitary plasmacytoma.

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Abstract

[Indexed for MEDLINE] 4. Recent Results Cancer Res. 2011;183:285-91. doi: 10.1007/978-3-540-85772-3_13. Radiotherapy. Krause S(1), Debus J, Neuhof D. Author information: (1)Department of Radiation Oncology, University of Heidelberg, Heidelberg, Germany. sonja.krause@med.uni-heidelberg.de Solitary plasmocytoma occurring in bone (solitary plasmocytoma of the bone, SBP) or in soft tissue (extramedullary plasmocytoma, EP) can be treated effectively and with little toxicity by local radiotherapy. Ten-year local control rates of up to 90% can be achieved. Patients with multiple myeloma often suffer from symptoms such as pain or neurological impairments that are amenable to palliative radiotherapy. In a palliative setting, short treatment schedules and lower radiation doses are used to reduce toxicity and duration of hospitalization. In future, low-dose total body irradiation (TBI) may play a role in a potentially curative regimen with nonmyeloablative conditioning followed by allogenic peripheral blood stem cell transplantation. DOI: 10.1007/978-3-540-85772-3_13