Classifications for radiographic evaluation of radiolucent bone lesions have poor inter- and intra-observer agreement.

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Abstract

[Indexed for MEDLINE] Conflict of interest statement: Declarations. Ethics approval and consent to participate: This study was subject to ethics board approval and deemed IRB exempt (SUNY Upstate IRB, Syracuse, NY #2191652-1). Participants were limited to voluntary and informed orthopedic trainees and faculty. All included images were deidentified. Consent for publication: Not applicable. Competing interests: One author (TAD) has received funding from: BMC Musculoskeletal Disorders: Editorial or governing board. Bone Support (Cerament): Paid consultant. BoneSupport (Cerament): Research support. Clinical Orthopaedics and Related Research: Editorial or governing board. eMedicine: Editorial or governing board; Publishing royalties, financial or material support. Journal of Orthopaedic Research: Editorial or governing boardJournal of Surgical Oncology: Editorial or governing board. Journal of the American Academy of Orthopaedic Surgeons: Publishing royalties, financial or material support. Medicina: Editorial or governing board. Open Journal of Orthopedics: Editorial or governing board. OREF: Research support. PLOS One: Editorial or governing board. Stryker: Research support. Up To Date: Publishing royalties, financial or material support. Wolters Kluwer Health - Lippincott Williams & Wilkins: Publishing royalties, financial or material support. Wright Medical Technology, Inc.: Research support. The remaining authors (TJW, SMP, KAM, SC) do not have any disclosures. 11. Radiologe. 1998 Jun;38(6):509-22. doi: 10.1007/s001170050386. [Ewing sarcoma. Diagnostic imaging]. [Article in German] Henk CB(1), Grampp S, Wiesbauer P, Zoubek A, Kainberger F, Breitenseher M, Mostbeck GH, Imhof H. Author information: (1)Abteilung Osteologie/MR, NAKH, Universitätsklinik für Radiodiagnostik, Ludwig-Boltzmann-Institut für radiologisch-onkologische Tumordiagnostik, Wien. Ewing's sarcoma is a highly malignant neoplasm of the bone whose origin is still uncertain. A strong relationship exists between Ewing's sarcoma and tumors of neural origin (Ewing family of tumors). Ewing's sarcoma must be distinguished from other round-cell tumors like lymphoma and neuroblastoma and also must be differentiated from osteogenic sarcomas. On plain radiographs, Ewing's sarcoma appears as a lytic or mixed lytic-sclerotic, rarely as predominantly sclerotic lesion with margins Lodwick grade III. It is located primarily in the diaphyseal and metadiaphyseal regions of the long bones of the lower extremities. A large soft tissue tumor is usually present. Magnetic resonance imaging is the imaging modality of choice to evaluate the extent of the primary lesion, to monitor the response to neoadjuvant chemotherapy and to follow up non-resected Ewing's sarcomas. Bone scintigraphy is necessary to detect skeletal metastasis, and 201thallium scanning has been shown to be sensitive in the monitoring of treatment response. Today, computed tomography is not longer used to image the tumor site; however, spiral CT of the lungs plays a central role as a staging and follow-up tool. DOI: 10.1007/s001170050386