[Imaging of bone metastases].

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Abstract

[Indexed for MEDLINE] 4. Semin Ultrasound CT MR. 2021 Apr;42(2):114-122. doi: 10.1053/j.sult.2020.08.014. Epub 2020 Sep 1. An Approach to Undiagnosed Bone Tumors. Costelloe CM(1), Madewell JE(2). Author information: (1)The University of Texas MD Anderson Cancer Center, Department of Musculoskeletal Imaging, Houston, TX. Electronic address: ccostelloe@mdanderson.org. (2)The University of Texas MD Anderson Cancer Center, Department of Musculoskeletal Imaging, Houston, TX. The radiographic appearance of primary bone tumors is important for initial diagnosis and often augments histopathological analysis. The original grading system relied on the radiographic analysis of the margin of the lesions to determine tumor aggression, which often corresponds with malignant potential. The recently developed, modified Lodwick-Madewell grading system also incorporates the appearance of lesion margins on radiographs but also considers the change in margins on serial radiographs and includes a category for clinically suspected, radiographically occult, aggressive lesions. This article reviews the prior and modified grading systems, and the concepts necessary for proper interpretation of the initial appearance of bone tumors which often determines the radiologist's recommendation for biopsy or follow-up imaging. Copyright © 2020 Elsevier Inc. All rights reserved. DOI: 10.1053/j.sult.2020.08.014