Bone in Parathyroid Diseases Revisited: Evidence From Epidemiological, Surgical and New Drug Outcomes.

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Abstract

[Indexed for MEDLINE] 2. J Am Acad Orthop Surg. 2006 May;14(5):303-11. doi: 10.5435/00124635-200605000-00006. Renal osteodystrophy. Tejwani NC(1), Schachter AK, Immerman I, Achan P. Author information: (1)Department of Orthopaedics, Bellevue Hospital, New York, NY 10016, USA. The incidence of chronic renal disease is increasing, and the pattern of renal osteodystrophy seems to be shifting from the classic hyperparathyroid presentation to one of low bone turnover. Patients with persistent disease also live longer than previously and are more physically active. Thus, patients may experience trauma as a direct result of increased physical activity in a setting of weakened pathologic bone. Patient quality of life is primarily limited by musculoskeletal problems, such as bone pain, muscle weakness, growth retardation, and skeletal deformity. Chronic renal disease also increases the risk of comorbidity, such as infection, bleeding, and anesthesia-related problems. Current treatment strategies include dietary changes, plate-and-screw fixation, and open reduction and internal fixation. DOI: 10.5435/00124635-200605000-00006