Journal of reconstructive microsurgery | 2021 | Black CK, Ormiston LD, Fan KL, Kotha VS
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[Indexed for MEDLINE] Conflict of interest statement: None declared. 6. Orthop Clin North Am. 2015 Jan;46(1):77-87. doi: 10.1016/j.ocl.2014.09.013. Epub 2014 Oct 22. Novel applications of osseointegration in orthopedic limb salvage surgery. Monument MJ(1), Lerman DM(1), Randall RL(2). Author information: (1)Sarcoma Services, Department of Orthopaedic Surgery, Huntsman Cancer Institute, Primary Children's Medical Center, University of Utah, 2000 Circle of Hope, Room 4260, Salt Lake City, UT 84112, USA. (2)Sarcoma Services, Department of Orthopaedic Surgery, Huntsman Cancer Institute, Primary Children's Medical Center, University of Utah, 2000 Circle of Hope, Room 4260, Salt Lake City, UT 84112, USA. Electronic address: Lor.Randall@hci.utah.edu. Osseointegration is a biologic process vital to modern endoprosthetic fixation in orthopedic surgery. Numerous engineering advancements have improved the utilization of this technology in orthopedics; however, issues such as stress shielding, aseptic loosening, and bone loss remain an ongoing challenge. These host responses are especially problematic in limb salvage surgery. Novel applications of osseointegration have been developed to address some of these fixation issues with massive tumor endoprostheses. This articles reviews osseointegration and emerging novel applications of this technology in limb salvage surgery and future prosthetics for amputees. Copyright © 2015 Elsevier Inc. All rights reserved. DOI: 10.1016/j.ocl.2014.09.013
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