Synovial neoformations and tumours.

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Abstract

[Indexed for MEDLINE] 15. Am J Surg Pathol. 1992 Oct;16(10):1017-20. doi: 10.1097/00000478-199210000-00014. Intraarticular synovial sarcoma. McKinney CD(1), Mills SE, Fechner RE. Author information: (1)Department of Pathology, University of Virginia Health Sciences Center, Charlottesville 22908. A 43-year-old man presented with decreased range of motion in his left knee and a painful medial joint mass that was grossly visible. Arthroscopy demonstrated a mobile, flat mass 3 cm in diameter in the knee joint that seemed to be loosely tethered to the synovium. The mass was excised, and light microscopic examination demonstrated a biphasic synovial sarcoma. There was no transition with the attached normal synovium. Immunohistochemically, the epithelial component was intensely positive for epithelial membrane antigen and cytokeratins (CAM 5.2 and AE 1/AE 3), and the spindle cell component was focally positive for these markers. The patient has no evidence of disease 9 years after only local excision. Although the term synovial sarcoma suggests a relationship to normal synovium, only rarely has truly intraarticular disease been reported. DOI: 10.1097/00000478-199210000-00014