Charcot Neuroarthropathy: From the Laboratory to the Bedside.

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Abstract

[Indexed for MEDLINE] 20. Foot Ankle Clin. 2022 Dec;27(4):835-846. doi: 10.1016/j.fcl.2022.08.005. Arthrodesis in the Deformed Charcot Foot. Rosemberg DL(1), Sposeto RB(2), Godoy-Santos AL(3). Author information: (1)Departamento de Ortopedia e Traumatologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Dr. Ovídio Pires de Campos, 333 - Cerqueira César, São Paulo, São Paulo 05403-010, Brazil; Hospital Israelita Albert Einstein, São Paulo, Av. Albert Einstein, 627/701 - Morumbi, São Paulo - SP, 05652-900, Brazil; International Scholar at the Midwest Orthopedics at Rush (MOR), 1620 W. Harrison St., Chicago, IL, 6012, USA; RUSH-IBTS International Fellowship Program, 1620 W. Harrison St., Chicago, IL, 6012, USA. Electronic address: dr.dovr@gmail.com. (2)Departamento de Ortopedia e Traumatologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Dr. Ovídio Pires de Campos, 333 - Cerqueira César, São Paulo, São Paulo 05403-010, Brazil. (3)Departamento de Ortopedia e Traumatologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Dr. Ovídio Pires de Campos, 333 - Cerqueira César, São Paulo, São Paulo 05403-010, Brazil; Hospital Israelita Albert Einstein, São Paulo, Av. Albert Einstein, 627/701 - Morumbi, São Paulo - SP, 05652-900, Brazil. Charcot neuroarthropathy (CN) is a systemic disease that causes fractures, dislocations, and deformities involving the foot and ankle, resulting in substantial risk of ulceration, infection, and function loss. Early recognition and prevention of collapsing foot and ankle are still the best options for the management of patients with diabetic CN. For a successful arthrodesis procedure, the principles of adequate joint preparation, deformity correction, and soft tissue protection and care are essentials, associated with robust fixation (internal and/or external), use of different biological graft options in segmental losses, and prolonged off-loading. Copyright © 2022 Elsevier Inc. All rights reserved. DOI: 10.1016/j.fcl.2022.08.005