Archives of orthopaedic and trauma surgery | 2021 | Batailler C, Swan J, Marinier ES, Servien E
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[Indexed for MEDLINE] 12. Front Bioeng Biotechnol. 2024 Apr 15;12:1352794. doi: 10.3389/fbioe.2024.1352794. eCollection 2024. Posterior tibial slope influences joint mechanics and soft tissue loading after total knee arthroplasty. Guo N(1), Smith CR(2), Schütz P(1), Trepczynski A(3), Moewis P(3), Damm P(3), Maas A(4)(5), Grupp TM(4)(5), Taylor WR(1), Hosseini Nasab SH(1). Author information: (1)Institute for Biomechanics, Department of Health Sciences and Technology, ETH Zürich, Zürich, Switzerland. (2)Department of Biomedical Engineering, Steadman Philippon Research Institute, Vail, CO, United States. (3)Julius Wolff Institute, Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin, Germany. (4)Aesculap AG, Tuttlingen, Germany. (5)Department of Orthopaedic and Trauma Surgery, Ludwig Maximilians University Munich, Musculoskeletal University Center Munich (MUM), Munich, Germany. As a solution to restore knee function and reduce pain, the demand for Total Knee Arthroplasty (TKA) has dramatically increased in recent decades. The high rates of dissatisfaction and revision makes it crucially important to understand the relationships between surgical factors and post-surgery knee performance. Tibial implant alignment in the sagittal plane (i.e., posterior tibia slope, PTS) is thought to play a key role in quadriceps muscle forces and contact conditions of the joint, but the underlying mechanisms and potential consequences are poorly understood. To address this biomechanical challenge, we developed a subject-specific musculoskeletal model based on the bone anatomy and precise implantation data provided within the CAMS-Knee datasets. Using the novel COMAK algorithm that concurrently optimizes joint kinematics, together with contact mechanics, and muscle and ligament forces, enabled highly accurate estimations of the knee joint biomechanics (RMSE
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